VITRO

作品数:343被引量:791H指数:13
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相关领域:生物学更多>>
相关作者:付瑾崔岩山庄焱张文广杜泽英更多>>
相关机构:中国科学院中国科学院研究生院上海交通大学中国医学科学院北京协和医学院更多>>
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Liquid Biopsy Instrument for Ultra-Fast and Label-Free Detection of Circulating Tumor Cells
《Research》2025年第1期803-814,共12页Shu Zhu Zhixian Zhu Chen Ni Zheng Zhou Yao Chen Dezhi Tang Kefan Guo Shuai Yang Kang Liu Zhonghua Ni Nan Xiang 
supported by the National Natural Science Foundation of China(52375562,51875103,and 81727801);the Natural Science Foundation of Jiangsu Province(BK20190064);the“333”Project of Jiangsu Province.
Rapid diagnosis and real-time monitoring are of great important in the fight against cancer.However,most available diagnostic technologies are time-consuming and labor-intensive and are commonly invasive.Here,we descr...
关键词:analysis circulating tumor cells ctcs liquid biopsy liquid biopsy instrument impedance cytometrywhich diagnostic technologies vitro experiments deep learning algorithm inertial microfluidics 
Microfluidic platforms for monitoringcardiomyocyte electromechanical activity
《Microsystems & Nanoengineering》2025年第1期23-44,共22页Wei Wang Weiguang Su Junlei Han Wei Song Xinyu Li Chonghai Xu Yu Sun Li Wang 
supported by the National Natural Science Foundation of China(NO.62371267,62121003);Key R&D Program of Shandong Province(Major innovation project)(2022CXGC020501);Science,Education and Industry Integration Innovation Pilot Project from Qilu University of Technology(Shandong Academy of Sciences)(NO.2022JBZ02-01);Research Leader Studio in Colleges and Universities of Jinan(NO.2021GXRC083);Innovation Team of Organ-on-a-Chip Manufacturing Key Technologies(NO.202333015,Funded by Jinan Science and Technology Bureau);Young Innovative Talents Introduction&Cultivation Program for Colleges and Universities of Shandong Province(Granted by Department of Education of Shandong Province,Sub-Title 1:Innovative Research Team of High-Performance Integrated Device,Sub-Title 2:Innovative Research Team of Advanced Energy Equipment);Shandong Provincial Natural Science Foundation(ZR2023QH405)。
Cardiovascular diseases account for ~40% of global deaths annually. This situation has revealed the urgent need forthe investigation and development of corresponding drugs for pathogenesis due to the complexity of res...
关键词:cardiac drug screeningand detection techniques microfluidic platforms investigation development corresponding drugs pathogenesis disease modeling accurate fluid control cardiovascular diseases vitro cardiomyocyte model 
Ultrasound Pancreatic Stimulation: A Novel Strategy for Insulin Release and Diabetes Management
《Journal of Bio-X Research》2024年第4期165-172,共8页Niloufar Khalafpour 
Diabetes mellitus remains a global health care challenge,promoting the search for innovative treatments.In vivo and in vitro studies have shown the potential benefits of ultrasound(US)on enhancing insulin release and ...
关键词:diabetes management enhancing insulin release stimulating pancreatic function vitro studies ULTRASOUND diabetes mellitus pancreatic stimulation insulin release 
Leveraging diverse cell-death patterns to predict the clinical outcome of immune checkpoint therapy in lung adenocarcinoma:Based on muti-omics analysis and vitro assay被引量:3
《Oncology Research》2024年第2期393-407,共15页HONGYUAN LIANG YANQIU LI YONGGANG QU LINGYUN ZHANG 
National Natural Science Foundation of China(Grant No.81273297);Shenyang Science and Technology Plan.Public Health R&D Special Project(21-173-9-67).
Advanced LUAD shows limited response to treatment including immune therapy.With the development of sequencing omics,it is urgent to combine high-throughput multi-omics data to identify new immune checkpoint therapeuti...
关键词:Lung adenocarcinoma Programmed cell death Iron-death Drug sensitivity Cancer therapy 
Gastroprotective Effect of Alpinia zerumbet(Pers.)Burttet Smith on Ethanol-induced Gastric Ulcers in vivo and vitro
《Medicinal Plant》2023年第5期65-71,共7页Qing WEI Shanshan LIANG Yuechun YANG Jing ZHANG 
Supported by Guizhou Provincial Basic Research Program(Natural Science)(ZK[2022]-492&[2020]1Y045);the National Natural Science Foundation of China(82260767).
[Objectives]To explore the protective effect of Alpinia zerumbet(Pers.)Burttet Smith ethanol extraction(YSJ)on gastric ulcers.[Methods]The ethanol-induced gastric ulcer model was generated by male Kunming mice.The mic...
关键词:Alpinia zerumbet(Pers.)Burttet Smith Gastric ulcer Inflammatory factors 
血管性血友病因子抗原与VITRO评分对乙型肝炎肝硬化预后的预测价值被引量:3
《陕西医学杂志》2023年第8期1059-1062,共4页庄焱 
国家自然科学基金资助面上项目(81970544)。
目的:探讨血管性血友病因子抗原(vWF:Ag)与VITRO评分对乙型肝炎肝硬化预后的预测价值。方法:乙型肝炎肝硬化患者185例,收集临床数据,检测血浆vWF:Ag水平,计算VITRO评分;单因素分析评估血浆vWF:Ag水平和VITRO评分与Child分级之间的关系;X...
关键词:血管性血友病因子 VITRO评分 慢性乙型肝炎 肝硬化 凝血 死亡 
Effect of Toosendan Fructus before and after stir-frying process extract on CYP450 enzyme activities in rats in vivo and vitro by cocktail probe drug method
《TMR Modern Herbal Medicine》2023年第2期1-8,共8页Yu-Feng Hu Si-Yuan Ma Meng-Lin Wang Shuang-Hui Shi Xiao-Tong Wei Ming-Rui Jiang Hui-Nan Wang Jing-Qiu Zhang Qian-Qian Liu Ying-Zi Wang 
supported by Natural Key R&D Program of China(No.2018YFC1707000).
Background:The traditional Chinese medicine Toosendan Fructus has certain hepatotoxicity,which is used after being processed by stir-frying to attenuate toxicity.However,there are few studies on its attenuating toxici...
关键词:Toosendan Fructus TOXICOLOGY pharmacokinetics CYP450 
GCI和VITRO评分对乙型肝炎相关肝硬化患者静脉曲张出血的预测价值被引量:2
《临床检验杂志》2022年第11期830-834,共5页徐帅 朴美花 吴政燮 黄媛 韩才均 
延边大学应用基础项目(延大科合字2020-45)。
目的探讨糖萼素(GC)指数(GCI)和血管性血友病因子(vWF)与血小板比值(VITRO)评分在预测门静脉高压相关静脉曲张出血中的作用。方法纳入62例乙型肝炎相关肝硬化患者,至少随访12个月,所有患者均进行实验室检查和上消化道内镜检查。用ELISA...
关键词:乙型肝炎 肝硬化 静脉曲张 血管性血友病因子 糖萼素 
Optimization of Three-Dimensional Culture Conditions of HepG2 Cells with Response Surface Methodology Based on the VitroGel System
《Biomedical and Environmental Sciences》2022年第8期688-698,共11页WANG Jing Bo QIN Wen YANG Zhuo SHEN Shi MA Yan WANG Li Yuan ZHUO Qin GONG Zhao Long HUO Jun Sheng CHEN Chen 
funded by Toxicity Evaluation of Key Contaminants in Health Food by Cell-based Test Models and the Mechanism Analysis [2018YFC1602104]
Objective This study optimizes three-dimensional(3D) culture conditions of HepG2 using response surface methodology(RSM) based on the VitroGel system to facilitate the cell model in vitro for liver tissues.Method HepG...
关键词:Response surface methodology The three-dimensional culture HYDROGEL 
Sperm-specific protein ACTL7A as a biomarker for fertilization outcomes of assisted reproductive technology被引量:2
《Asian Journal of Andrology》2022年第3期260-265,共6页Tian-Ying Yang Ying Chen Guo-Wu Chen Yi-Si Sun Zhi-Chao Li Xiao-Rong Shen Yi-Ni Zhang Wen He Dan Zhou Hui-Juan Shi Ai-Jie Xin Xiao-Xi Sun 
supported by the Foundation of Shanghai Municipal Health Commission(No.202140340);National Natural Science Foundation of China(No.82171603);Foundation of Science and Technology Commission of Shanghai Municipality(No.17JC1400902,No.20Z21900402).
Obtaining high-quality embryos is one of the key factors to improve the clinical pregnancy rate of assisted reproductive technologies(ART).So far,the clinical evaluation of embryo quality depends on embryo morphology....
关键词:actin-like 7A assisted reproductive technology BIOMARKER embryo quality in‑vitro fertilization outcomes 
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