This work was financially supported by National Natural Science Foundation of China(No.51622701 and 51425201);the National Basic Re-search Program of China(973 Program)(Grant No.2014CB239501);Beijing Nova Program(Z181100006218006),the Fundamental Research Funds for the Central Universities(No.FRF-TP-16-001C1);the State Key Laboratory of Alternate Electrical Power System with Renewable Energy Sources(Grant No.LAPS19001).
High-voltage direct current(HVDC)power cables have been paid more attention due to the big issue concerning the main insulation materials.The residues in the industrial production process will cause space charge gener...
The National Natural Science Foundation of China(Grant No.21778006 and 20932001);the Ministry of Science and Technology of China(Grant No.2012AA022501)
Cationic lipids have been applied to siRNA delivery for tumor therapeutics. However, the excess positive charges of these nanoplexes may lead to high cytotoxicity and nonnegligible immunogenicity both in vitro and in ...
Supported by the National Key Technology Research and Development Program of the Ministry of Science and Technology of China(No.2012BAI30B00)
2-Benzyl-7-butoxyl-9-isobutyl-1-methyl-β-carboline bromide(H-2-65) was synthesized by the reaction of Harmine with 1-iodobutane via N9-alkylation, demethyl and N2-quaternarization to obtain the new compound. The re...
Supported by the National Natural Science Foundation of China(21276073,21136004);the National Basic Research Program of China(2009CB219902);the Fundamental Research Funds for the Central Universities of China(222201313001)
Vapor pressures were measured for acetonitrile+1-butyl-3-methylimidazolium chloride([C4mim][Cl]),+1-butyl-3-methylimidazolium tetrafluoroborate([C4mim][BF4])and+1-hexyl-3-methylimidazolium chloride([C6mim][Cl])at temp...
supported by the National Natural Science Foundation of China(21172220);the National Basic Research Program of China(2009CB940900)
We designed a series of 2-methylpyrimidine derivatives as new BCR-ABL inhibitors using scaffold-hopping strategy.These synthetic compounds exhibited significant inhibition against a broad spectrum of Bcr-Abl mutants i...
Supported by the National Key Basic Research Program of China(973 Program)(2012CB725204 and 2012CB721104);the Natural Science Foundation of Jiangsu Province(No.BK20130913);Program for Changjiang Scholars and Innovative Research Team in University(No.IRT1066);the Priority Academic Program Development of Jiangsu Higher Education Institution
The title compound(S)-N-(hexahydro-2-oxo-1H-azepin-3-yl)-3-phenyl-2-propenamide(C15H18N2O2, Mr = 258.31) was synthesized by the reaction of(S)-α-amino-ε-caprolactam with 3-phenyl-2- propenoyl chloride. Its c...
supported by the National Basic Research Program of China(2010CB126100);the National Natural Science Foundation of China(21002037 and 21172090);supported in part by the PCSIRT(No.IRT0953)
A new crystal of 4-fluoro-N-(2-methyl-5-((2-(p-tolyloxy)acetamido)methyl)pyrimi- din-4-yl)benzamide has been prepared at room temperature and characterized by 1H NMR, 13C- NMR, IR, MS, elemental analysis and X...
Supported by the National Basic Research Program of China(No.2010CB126106), the Fundamental Research Funds for the Central Universities and Natural Science Foundation of China(No.31000861).
A series of novel 1-substituted phenyl or glycosyl 1,2,3-triazoles was designed and synthesized by azide-alkyne 1,3-dipolar cyeloaddition between 4,6-dimethoxy-2-[(4-prop-2-ynyl)piperazin-l-yl]pyrimidine and each of...
supported by National Basic Research Program of China (2012CB910604);National Natural Science Foundation of China (21205027,21005079,20935004);Analytical Method Innovation Program of Ministry of Science and Technology of China (2010IM030500);Natural Science Foundation of Hebei Province (B2012201095)
The cationic reagent 1-(3-aminopropyl)-3-butylimidazolium bromide(BAPI) was exploited for the derivatization of carboxyl groups on peptides.Nearly 100% derivatization efficiency was achieved with the synthetic peptide...