supported by the National Natural Science Foundation of China(grant number 81273110);the Health Industry Research Special Funds for public welfare projects(grant number 201402021);the National Key Technology Research and Development Program(grant number 2014BAI12B02)
Objective To investigate acrylamide (ACR)-induced subacute neurotoxic effects on the central nervous system (CNS) at the synapse level in rats. Methods Thirty-six Sprague Dawley (SD) rats were randomized into th...
the National Natural Science Funding of China(No.30872088,81372969)
The purpose of this study was to study the role of neurofilament (NF) mRNA and calpain in NF reduction of acrylamide (ACR) neuropathy. Male Wistar adult rats were injected i.p. every other day with AER (20 mg/kg....
supported by the National Science and Technology Support Program(2012BAK01B00)
Objective To investigate the immunotoxicity of acrylamide (ACR) in female BALB/c mice.Methods A total of 200 female mice weighing 18-22 g were randomly divided into four clusters based on body weight, and each weigh...
supported by the National Natural Science Fund of China (No.30872088);Technology Development Plan of Shandong Province(No.2012GSF11854)
To study biomarker of acrylamide (ACR) induced neuropathy, Wistar rats received 20 or 40 mg/kg of ACR by ip injection and the levels of light neurofilament (NF-L), middle NF (NF-M), heavy NF (NF-H), β-actin, ...
supported by the National Basic Resarch Program of China(2012CB20804);grant from Ministry of Health,PR China(200902009)
Objective To assess the current status of the acrylamide in the Chinese food supply, the dietary acrylamide exposure in the Chinese population and to estimate the public health risks of the current consumption. Method...
Objective To determine residual acrylamide in medical polyacrylamide hydrogel by high performance liquid chromatography tandem mass spectroscopy (HPLC-MS). Methods After 13C3 labeled acrylamide was added, the sample...
Project supported by the National Natural Science Foundation of China.
A HPLC Assay was developed to identify and measure the metabolite of acrylamide, mercapturic acid, N-Acetyl-s-(propionamide)-cysteine (APC) in urine. O-phthalaldehyde (OPA) was utilized as a precolumn derivatizing age...