ANTI-TUMOR

作品数：366被引量：1036H指数：14
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相关机构：北京大学中国药科大学重庆医科大学山东大学更多>>
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Immune-adjuvant loaded Bi2Se3 nanocage for photothermal-improved PD-L1 checkpoint blockade immune-tumor metastasis therapy被引量：2
《Nano Research》2019年第8期1770-1780,共11页Yilin Song Yidan Wang Siyu Wang Yu Cheng Qianglan Lu Lifang Yang Fengping Tan Nan Li 
supported by the National Basic Research Project (973 Program) of China (No.2014CB932200);the National Natural Science Foundation of China (Nos.81503016, 81771880, and 81401453);the Application Foundation and Cutting-edge Technologies Research Project of Tianjin (Young Program)(No.15JCQNJC13800).
Checkpoint blockade based immune therapy has shown to be effective but benefit only the minority of patients whose tumors have been pre-infiltrated by T cells. To overcome this obstacles, a PEG-modified Bi2Se3 nanocag...
关键词：Bi2Se3 NANOCAGE R848 checkpoint BLOCKADE photothermal-immune THERAPY ANTI-TUMOR metastasis 
A novel nanogel delivery of poly-α,β-polyasparthydrazide by reverse microemulsion and its redox-responsive release of 5-Fluorouridine被引量：1
《Asian Journal of Pharmaceutical Sciences》2016年第6期735-743,共9页Jingwen Guo Yan Wang Jing Wang Xin Zheng Di Chang Siling Wang Tongying Jiang 
National Basic Research Program of China(973 Program)(No.2015CB932100);National Natural Science Foundation of China(No.81473165);Liaoning Provincial Key Laboratory of Drug Preparation Design&Evaluation of Liaoning Provincial Education Department(LZ2014045);Liaoning Provincial Key Laboratory of Studying the Modern Drug preparations.
To achieve GSH-responsive 5-Fluorouridine(5-FU) delivery, a novel family of nanogel drug carriers has been successfully prepared. The new class of PAHy-based nanogels was prepared by the crossing-link reaction of poly...
关键词：PAHy-based NANOGEL High drug loading Redox-responsivity RELEASE properties SIGNIFICANT ANTI-TUMOR therapeutic efficacy 
The anti-tumor efficacy of c9,t11-CLA-PTX and t10,c12-CLA-PTX on MCF-7 breast cancer cells:in vitro and in vivo
《Journal of Chinese Pharmaceutical Sciences》2014年第11期751-759,共9页杨科 李星火 李丹 柯曦宇 张烜 张强 
National Natural Science Foundation of China (Grant No.81172992);the National Basic Research Program of China (973 Program,Grant No.2013CB932501);Innovation Team of Ministry of Education (Grant No.BMU20110263)
Considering the results of our previous research that conjugated linoleic acid mixture-paclitaxel （CLA-mixture-PTX） possesses anti-tumor activity against melanoma and brain glioma, the purpose of this study was to i...
关键词：C9 tl 1-CLA-PTX T10 c12-CLA-PTX Apoptosis Cell cycle Cellular uptake Anti-tumor efficacy 
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