ANTIHYPERTENSIVE

作品数：63被引量：118H指数：6
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Discovery and mechanism of anti-hypertensive effect of a novel tripeptide(SYP)from medicinal fungus Ganoderma lingzhi
《Food Science and Human Wellness》2025年第2期509-524,共16页Qiang Wu Feijun Luo Jia Huang Ping Huang Yongnan Liu Xiaoling Wang Gaoqiang Liu 
supported by the National Natural Science Foundation of China(32071673 and 32202573);the Program of Hunan Science and Technology Innovation Team(2021RC4063);the Natural Science Foundation of Hunan Province(2021JJ31151 and 2022JJ50028);the Key Scientific Research Project of Hunan Education Department(22A0538)。
Ganoderma lingzhi is a new species of the prize medicinal mushroom Ganoderma(Agaricomycetes).Using angiotensin I-converting enzyme(ACE)as a target,a tripeptide Ser-Tyr-Pro(SYP)was discovered with preponderant ACE inhi...
关键词：Antihypertensive peptide Ganoderma lingzhi Gene microarray Molecular mechanism 
Response surface optimization of preparation parameters and evaluation of the antioxidant and antihypertensive activities of Spirulina protein hydrolysates
《Journal of Oceanology and Limnology》2025年第1期196-209,共14页Qishan SUO Zhenzhen DENG Yang YUE Jing WANG Ning WU Lihua GENG Quanbin ZHANG 
Supported by the Science and Technology Project of Fujian Province(Nos.2023T3034,2020N3011);the Innovation Academy for Drug Discovery and Development;Chinese Academy of Sciences。
Safety,high protein content,and the numerous health benefits make Spirulina an outstanding source of bioactive peptides.Peptides from Spirulina,which exhibit antioxidant,anti-inflammatory,and antihypertensive effects,...
关键词：antioxidant activity antihypertensive effect angiotensin converting enzyme inhibition response surface methodology SPIRULINA 
Exploring the antihypertensive mechanism of Prunella vulgaris through integrated network pharmacology analysis
《Journal of Chinese Pharmaceutical Sciences》2024年第11期1068-1081,共14页Na Sun Yujing Wang Caihong Zhou Huanhuan Kang Shuo Ma Yu Zhang Yuhan Yuan Xin Zhang Linxuan Jin Wenqian Li Xinru Wu Penghua Shu 
National Natural Science Foundation of China(Grant No.21702178);Training Plan of Young Backbone Teachers in Universities of Henan Province(Grant No.2021GGJS144);Key Scientific Research Program in Universities of Henan Province(Grant No.22A350009 and 23A350012);National Undergraduate Training Program for Innovation and Entrepreneurship(Grant No.202410480007 and 202310480020);Undergraduate Training Program for Innovation and Entrepreneurship of Henan Province(Grant No.202210480020 and 202210480021);Scientific Research Innovation Team of Xuchang University(Grant No.2022CXTD007);Horizontal Cooperation Project(Grant No.2023HX181);Undergraduate Training Program for Innovation and Entrepreneurship of Xuchang University(Grant No.X202210480016)。
Prunella vulgaris,a traditional Chinese medicine(TCM),exerts a significant hypotensive effect,particularly in managing various forms of hypertension.Nonetheless,the precise antihypertensive constituents and their resp...
关键词：Prunella vulgaris L. Anti-hypertension Traditional Chinese medicine targets Natural active ingredients 
Outcome of COVID-19 infection in patients on antihypertensives:A cross-sectional study
《World Journal of Critical Care Medicine》2024年第3期42-52,共11页Sakthivadivel Varatharajan Gopal K Bohra Pradeep K Bhatia Satyendra Khichar Mahadev Meena Naveenraj Palanisamy Archana Gaur Mahendra K Garg 
approved by All India Institute of Medical Sciences-Jodhpur Institutional Review Board(AIIMS/IEC/2020-21/2003).
BACKGROUND Patients with coronavirus disease 2019(COVID-19)infection frequently have hypertension as a co-morbidity,which is linked to adverse outcomes.Antihypertensives may affect the outcome of COVID-19 infection.AI...
关键词：ANTIHYPERTENSIVE COVID-19 HYPERTENSION MORTALITY OUTCOME 
Network pharmacology and molecular docking:combined computational approaches to explore the antihypertensive potential of Fabaceae species被引量：1
《Bioresources and Bioprocessing》2024年第1期721-744,共24页Zainab Shahzadi Zubaida Yousaf Irfan Anjum Muhammad Bilal Hamna Yasin Arusa Aftab Anthony Booker Riaz Ullah Ahmed Bari 
Researchers supporting Project number RSP2024R346,King Saud University Riyadh Saudi Arabia.
Hypertension is a major global public health issue,affecting quarter of adults worldwide.Numerous synthetic drugs are available for treating hypertension;however,they often come with a higher risk of side effects and ...
关键词：Hypertension Herbal medicine PHYTOCHEMICALS FABACEAE Cassia species Network pharmacology Molecular docking 
Is medical management useful in Moyamoya disease?被引量：1
《World Journal of Clinical Cases》2024年第3期466-473,共8页Sombat Muengtaweepongsa Vatcharasorn Panpattanakul 
Moyamoya disease(MMD),characterized by progressive internal carotid artery stenosis and collateral vessel formation,prompts cerebral perfusion complications and is stratified into idiopathic and Moyamoya syndrome subt...
关键词：Moyamoya disease Cerebral infarction Antithrombotic management Transcranial doppler REVASCULARIZATION Intracerebral hemorrhage Antihypertensive intervention Lipid-lowering therapies 
Assessment of the Level of Metal(loid)s Pollution and Bioactive Compounds Screening of Anthill Soil
《Open Journal of Soil Science》2023年第11期474-489,共16页Graça K. Kandanda Festus S. Shafodino Simeon I. Ambuga Lamech M. Mwapagha 
The anthill soil is used by hypertensive elderly and teenagers from Oshikoto region (Namibia) and many of them testified stabilization of their blood pressure to normal after consuming the anthill soil-derived aqueous...
关键词：Anthill Soil Physicochemical Parameters Metal(loid)s Contamination ANTIHYPERTENSIVE Bioactive Compounds 
Antihypertensive prescribing patterns in non-dialysis dependent chronic kidney disease:Findings from the Salford Kidney Study
《World Journal of Nephrology》2023年第5期168-181,共14页Rajkumar Chinnadurai Henry H L Wu Jones Abuomar Sharmilee Rengarajan David I New Darren Green Philip A Kalra 
the National Institute of Health Research Manchester Biomedical Research Centre for their funding support in the SKS(NIHR203308).
BACKGROUND Hypertension is commonly observed in patients living with chronic kidney disease(CKD).Finding an optimal treatment regime remains challenging due to the complex bidirectional cause-and-effect relationship b...
关键词：HYPERTENSION Chronic kidney disease Antihypertensive agents Prescribing patterns Cardiovascular complications Renin angiotensin system blockers 
Core-shell lipid-polymeric nanoparticles for enhanced oral bioavailability and antihypertensive efficacy of KY5 peptide
《Chinese Chemical Letters》2023年第4期158-163,共6页Jingmei Yuan Mengran Guo Shengnan Zhao Jinhua Li Xinchun Wang Jian Yang Zhaohui Jin Xiangrong Song 
supported by the Youth Fund of National Natural Science Foundation of China (No. 82104081);the Science and Technology Project of Shenzhen (No. JCYJ20170413155047512);the 1.3.5 project for disciplines of excellence,West China Hospital,Sichuan University (No. ZYGD18020/ZYJC18006);the Sichuan Province Science and Technology Support Program (No. 2020JDRC0052);the Science and Technology Project of Xinjiang Production and Construction Corps (No. 2022AB020)。
Hypertension is the leading risk factor for death and disability, and hypertensive patients always need long-term oral antihypertensive drugs. Some bioactive peptides that extracted from animals or plants have shown e...
关键词：HYPERTENSION Core-shell lipid-polymeric nanoparticles KY5 Antihypertensive peptides Oral delivery 
Process optimization,texture and microstructure of novel kelp tofu被引量：3
《Food Science and Human Wellness》2023年第1期111-118,共8页Xianjiang Ye Li Chen Zhichen Su Xiaojuan Lin Jicheng Chen 
supported by the Natural Science Foundation of Fujian Province (2020J01558);the Expert Workstation of Fuzhou Hailin Food Co., Ltd
Laminaria japonica Aresch as an edible and medicine dual-purpose marine algae,has been gradually accepted by people.Tofu was Chinese traditional food,combining kelp function ingredients with tofu has practical value.T...
关键词：Laminaria japonica Aresch Enzymatic hydrolysis Antihypertensive peptide Kelp tofu 
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