ANTINEOPLASTIC

作品数:71被引量:285H指数:11
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相关领域:医药卫生更多>>
相关作者:宋琦李晓明陈绪军刘志苏艾中立更多>>
相关机构:中国人民解放军白求恩国际和平医院武汉大学北京军区总医院华中科技大学更多>>
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相关基金:国家自然科学基金天津市自然科学基金上海市教委科研基金上海市卫生局资助项目更多>>
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Increased sensitivity of colorectal cancer cell lines with microsatellite instability to 5-fluorouracil in vitro
《Chinese Medical Journal》2002年第7期1048-1052,151-152,共5页陈修煦 来茂德 黄琼 
OBJECTIVE: To study the relationship between sensitivity to 5-FU and the status of a panel of microsatellite loci in three human colon cancer cell lines. METHODS: Cell viability in several concentrations of 5-FU was a...
关键词:DNA-Binding Proteins Microsatellite Repeats Antimetabolites  Antineoplastic Base Pair Mismatch Carrier Proteins Colorectal Neoplasms DNA Repair Fluorouracil Humans Immunohistochemistry MutS Homolog 2 Protein Neoplasm Proteins Nuclear Proteins Polymerase Chain Reaction Proto-Oncogene Proteins Tumor Cells  Cultured 
The Effect of calmodulin antagonist berbaminederivative-EBB on hepatoma in vitro and in vivo被引量:2
《Chinese Medical Journal》2002年第5期759-762,157,共4页刘杰文 齐淑玲 朱惠芳 李卓 王彤 张金红 
ThisProjectwassupportedbyTianjinnaturalfoundationofsciences(9414 0 90 17);theMinisterofPublicHealthofChina (94 2 0 2 4)
OBJECTIVE: To evaluate the anti-hepatoma effect of Calmodulin antagonist 0 - 4-ethoxyl-butyl-Berbamine (EBB), one of the berbamine derivatives. METHODS: Monotetrazolium (MTT) method was used to analyze the effect of E...
关键词:BENZYLISOQUINOLINES Alkaloids Animals Antimetabolites  Antineoplastic CALMODULIN Carcinoma  Hepatocellular Cell Division Cell Survival Chromatography  Thin Layer Dose-Response Relationship  Drug Drug Synergism Fluorouracil Inhibitory Concentration 50 Liver Neoplasms  Experimental Mice Neoplasm Transplantation RNA  Messenger Research Support  Non-U.S. Gov't Tumor Cells  Cultured Tumor Suppressor Protein p53 
Antineoplastic mechanism of Octreotide action in human hepatoma被引量:4
《Chinese Medical Journal》2001年第11期47-50,106,共5页陈绪军 刘志苏 艾中立 
Objectives To investigate whether apoptosis can be induced by Octreotide in human hepatoma cells in vitro and elucidate the antineoplastic mechanism of Octreotide in hepatoma.Methods A cultured human hepatoma cell lin...
关键词:Octreotide liver neoplasm · apoptosis · in vitro  · antineoplastic  mechanism 
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