ANTISENSE_RNA

作品数：80被引量：260H指数：8
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相关作者：宋艳茹张景昱魏建华赵华燕刘惠荣更多>>
相关机构：中国科学院植物研究所中国科学院遗传与发育生物学研究所华中科技大学西北农林科技大学更多>>
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Curcumol ameliorates diabetic retinopathy via modulating fat mass and obesity-associated protein-demethylated MAF transcription factor G antisense RNA 1
《World Journal of Diabetes》2025年第4期220-235,共16页Han Rong Yu Hu Wei Wei 
BACKGROUND Diabetic retinopathy(DR)is a major microvascular complication of diabetes mellitus,leading to significant visual impairment and blindness among adults.Current treatment options are limited,making it essenti...
关键词：Diabetic retinopathy CURCUMOL MAF transcription factor G antisense RNA 1 Fat mass and obesity-associated protein Diabetes mellitus 
Long noncoding RNA semaphorin 6A-antisense RNA 1 reduces hepatocellular carcinoma by promoting semaphorin 6A mRNA degradation
《World Journal of Gastroenterology》2025年第13期138-151,共14页Song-Man Yu Min Zhang Sha-Lin Li Si-Ya Pei Li Wu Xing-Wang Hu Yan-Kun Duan 
Supported by Natural Science Foundation of Hunan Province,No.2021JJ41048 and No.S2019JJQNJJ2012;and Changsha Natural Science Foundation,No.kq2208400.
BACKGROUND Hepatocellular carcinoma(HCC)is a prevalent malignant tumor with a poor prognosis,which is often associated with chronic hepatitis B virus infection in China.Our previous study has shown that long non-codin...
关键词：Long noncoding RNA Semaphorin 6A antisense RNA 1 Semaphorin 6A Hepatocellular carcinoma Liver cancer 
Down-regulation of SEIPIN transcription attenuated the triacylglycerol accumulation in Nannochloropsis oceanica
《Journal of Oceanology and Limnology》2025年第1期187-195,共9页Lixian LIU Li GUO Hang LIU Xiaohui PAN Yanan ZONG Leili FENG Guanpin YANG 
Supported by the National Key R&D Program of China(No.2022YFF1102300);the Key R&D Program of Shandong Province,China(No.2022LZGC004);the National Natural Science Foundation of China(No.32102757);the Science&Technology Innovation Project of Laoshan Laboratory(No.LSKJ202203205);the Fundamental Research Funds for the Central Universities(No.202262001)。
Abnormal content of protein SEIPIN causes Berardinelli-Seip congenital lipodystrophy type 2(BSCL2)in humans.Previous studies have shown that Arabidopsis thaliana has evolved three SEIPIN homologs,determining the fusio...
关键词：Nannochloropsis oceanica antisense RNA SEIPIN neutral lipid 
Mechanistic link between long noncoding RNA and stability of oncogene reveals stemness and chemoresistance of hepatocellular carcinoma
《World Journal of Gastroenterology》2025年第7期160-162,共3页Yu-Bo Liang Xing-Ming Chen Wan-Ling Luo Yang Ke 
Supported by the National Natural Science Foundation of China,No.82103173 and No.82460461;Medical Subject Leader of Yunnan Province(General Surgery),No.D-2024029;Yunnan Fundamental Research Project for Excellent Young Scholars,No.202401AW070003;the Young and Mid-aged Academic and Technical Leader Reserve Talent Program of Yunnan Province,No.202205AC160063。
This letter comments on the recently published manuscript by Yu et al,in which the authors revealed a novel mechanism by which the m6A-modified long noncoding RNA kinesin family member 9-antisense RNA 1 promotes stemn...
关键词：Kinesin family member 9-antisense RNA 1 Hepatocellular carcinoma Ubiquitin-specific peptidase 1 Short stature homeobox 2 CHEMORESISTANCE 
Long Non-coding RNA PCED1B Antisense RNA 1 Promotes Cell Proliferation and Invasion in Hepatocellular Carcinoma by Regulating the MicroRNA-34a/CD44 Axis
《Current Medical Science》2024年第3期503-511,共9页Jian-gang BI Qi LI Yu-sheng GUO Li-ping LIU Shi-yun BAO Ping XU 
supported by the Medical Science and Technology Research Foundation of Guangdong Province(No.A2020559).
Objective This study aimed to examine the role of long non-coding RNA PCED1B antisense RNA 1(PCED1B-AS1)in the development of hepatocellular carcinoma(HCC).Methods A total of 62 pairs of HCC tissues and adjacent non-t...
关键词：long non-coding RNA PCED1B antisense RNA 1(PCED1B-AS1) hepatocellular carcinoma microRNA-34a(miR-34a) CD44 proliferation INVASION 
Prognostic value of the long noncoding RNA AFAP1-AS1 in cancers被引量：1
《Oncology and Translational Medicine》2023年第3期133-146,共14页Lixiu Zhu Jiawen Yan Guoqiang Xu Qiaoli Wang Tianrui Xu Ruixue Cao Chuanzheng Sun Yan Xi Wei Xiong 
Supported by a grant from the“Ten Thousand Plan”Youth Talent Project in Yunnan Province(no grant number is applicable).
Objective This meta-analysis explored whether the expression of actin filament-associated protein 1 antisense RNA 1(AFAP1-AS1)is related to the prognosis and clinicopathological features of patients with cancer.Method...
关键词：long noncoding RNA(lncRNA) actin filament-associated protein 1 antisense RNA 1(AFAP1-AS1) PROGNOSTIC META-ANALYSIS 
Alu antisense RNA ameliorates methylglyoxal-induced human lens epithelial cell apoptosis by enhancing antioxidant defense被引量：1
《International Journal of Ophthalmology(English edition)》2023年第2期178-190,共13页Pei-Yuan Wu Ning Ji Chong-Guang Wu Xiao-Die Wang Xin Liu Zhi-Xue Song Murad Khan Suleman Shah Ying-Hua Du Xiu-Fang Wang Li-Fang Yan 
Supported by the National Natural Science Foundation of China(No.81771499);the Natural Science Foundation of Hebei Province,China(No.H2018206099,No.H2021206460)。
AIM:To determine whether an antisense RNA corresponding to the human Alu transposable element(Aluas RNA)can protect human lens epithelial cells(HLECs)from methylglyoxal-induced apoptosis.METHODS:Cell counting kit-8(CC...
关键词：human Alu antisense RNA human lens epithelial cells methylglyoxal toxicity antioxidant defense apoptosis 
Anti-aging Effects of Alu Antisense RNA on Human Fibroblast Senescence Through the MEK-ERK Pathway Mediated by KIF15
《Current Medical Science》2023年第1期35-47,共13页Ning JI Chong-guang WU Xiao-die WANG Zhi-xue SONG Pei-yuan WU Xin LIU Xu FENG Xiang-mei ZHANG Xiu-fang WANG Zhan-jun LV 
supported by grants from the National Natural Science Foundation of China(No.81771499)and the Natural Science Foundation of Hebei Province,China(No.H2018206099 and No.H2021206460).
Objective:To investigate whether human short interspersed nuclear element antisense RNA(Alu antisense RNA;Alu asRNA)could delay human fibroblast senescence and explore the underlying mechanisms.Methods:We transfected ...
关键词：senescent fibroblast cell proliferation Alu antisense RNA KIF15 gene expression MEK-ERK signaling pathway cell cycle 
LncRNA AFAP1-AS1/miR-27b-3p/VEGF-C axis modulates stemness characteristics in cervical cancer cells被引量：6
《Chinese Medical Journal》2021年第17期2091-2101,共11页Meng Xia Li-Jun Duan Bi-Nan Lu Yu-Zhou Pang Zong-Ran Pang 
Background:Long non-coding RNA(lncRNA)actin filament-associated protein 1 antisense RNA 1(AFAP1-AS1)functions as a competing endogenous RNA to regulate target genes expression by sponging microRNAs(miRs)to play cancer...
关键词：Hyaluronic acid receptor cluster of differentiation 44 variant exon 6 Cell stemness Cervical cancer Long non-coding RNA actin filament-associated protein 1 antisense RNA 1 MicroRNA-27b-3p 
Long noncoding RNA TFAP2A-AS1 exerts promotive effects in non-small cell lung cancer progression via controlling the microRNA-548a-3p/CDK4 axis as a competitive endogenous RNA被引量：1
《Oncology Research》2021年第2期129-139,共11页YANG ZHANG LIXIA MA TINGTING ZHANG PEIDONG LI JIABIN XU ZHUO WANG 
supported by Jilin Province Cancer Hospital.
In this study,we mainly focus on probing expression profile and detailed functions of long non-coding RNA TFAP2A antisense RNA 1(TFAP2A-AS1)in non-small cell lung cancer(NSCLC).Moreover,the mechanisms played by TFAP2A...
关键词：TFAP2A antisense RNA 1 Lung cancer ceRNA pathway Therapeutic target 
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