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Changes in border-associated macrophages after stroke: Single-cell sequencing analysis
《Neural Regeneration Research》2026年第1期346-356,共11页Ning Yu Yang Zhao Peng Wang Fuqiang Zhang Cuili Wen Shilei Wang 
supported by Qingdao Key Medical and Health Discipline Project;The Intramural Research Program of the Affiliated Hospital of Qingdao University,No. 4910;Qingdao West Coast New Area Science and Technology Project,No. 2020-55 (all to SW)。
Border-associated macrophages are located at the interface between the brain and the periphery, including the perivascular spaces, choroid plexus, and meninges. Until recently, the functions of border-associated macro...
关键词：border-associated macrophages CLODRONATE hypoxia ISCHEMIA-REPERFUSION ischemic stroke liposomes neuroinflammation single-cell sequencing analysis STAT3 tumor necrosis factor 
Tale of mitochondria and mitochondria-associated ER membrane in patient-derived neuronal models of Wolfram syndrome
《Neural Regeneration Research》2025年第9期2587-2588,共2页Laetitia Aubry Timothy Barrett Sovan Sarkar 
supported by LifeArc Philanthropic Fund(P2019-0004);LifeArc Pathfinder Award;along with Wellcome Trust Seed Award(109626/Z/15/Z);FA PESP-UoB Strategic Collaboration Fund;Birmingham Fellowship(to SS);grants from Laboratoire d'Excellence Revive(Investissement d'Avenir;ANR-10-LABX-73);the Region lle-de-France via doctoral school Innovation Therapeutique,du Fondamentalàl'Appliqué(ED569)from Universite Paris-Saclay(to LA);Medical Research Council(MRC)Developmental Pathway Funding Scheme(DPFS)grant(MR/P007732/1)(to TB);supported by the Association Fran?aise contre les Myopathies(AFM-Téléthon)。
Mitochondria and mitochondria-associated endoplasmic reticulum membrane in neurodegenerative diseases:Mitochondria generate most of the chemical energy needed to power the biochemical reactions of cells,and thus are o...
关键词：OXIDATIVE CYCLE carboxylic 
Chronic hepatitis B triggering antineutrophil cytoplasmic antibodyassociated vasculitis complicated by glomerulonephritis:A case report
《World Journal of Clinical Cases》2025年第19期43-51,共9页Ming-Ru Li Li-Ya Li Juan Tang Jian Sun 
Supported by the Natural Science Foundation of Hunan Province,China,No.2023JJ30842.
BACKGROUND Hepatitis B virus(HBV)infection can lead to renal involvement,commonly manifested as HBV-associated glomerulonephritis(HBV-GN),which typically presents as nephrotic or nephritic syndrome.Antineutrophil cyto...
关键词：Hepatitis B virus Antineutrophil cytoplasmic antibody-associated vasculitis NEPHROPATHY Complications Immune complex Alveolar hemorrhage Plasma exchange Protein A immunoadsorption Case report 
Granulomatosis with polyangiitis induced by the anti-programmed cell death-1 inhibitor tislelizumab:A case report
《World Journal of Clinical Cases》2025年第15期56-62,共7页Jian-Hui Zhao Jing-Jiao Wang Yi-Wen Li 
BACKGROUND Immune checkpoint inhibitors(ICIs)are a new class of antitumor agents.They enhance antitumor effects by blocking inhibitory receptors and related ligands expressed on T cells.ICIs also modulate regular immu...
关键词：Tislelizumab Programmed cell death-1 inhibitor Granulomatosis with polyangiitis Anti-neutrophil cytoplasmic antibody-associated vasculitis Case report 
Efficacy and Safety of Erzhu Jiedu Decoction Granules in Treating Mid-advanced Hepatitis B Virus-Associated Primary Liver Cancer Patients with Pi(Spleen)-Deficiency and Dampness-Heat Syndrome
《Chinese Journal of Integrative Medicine》2025年第5期394-401,共8页CHENG Yang WANG Hao-yi WAN Cheng-yi SHI Jie-wen JIN Yuan-yuan HE Sheng-li YIN Bao-bing CHEN Jian-jie 
Supported by Shanghai Municipal Science and Technology Commission Foundation(No.21Y11922800);National Natural Science Foundation of China(No.82374189)。
Objective:To assess the efficacy and safety of Erzhu Jiedu Decoction(EZJDD)Granules in treating mid-advanced hepatitis B virus-associated primary liver cancer(HBV-PLC)patients with Pi(Spleen)-deficiency and dampness-h...
关键词：Erzhu Jiedu Decoction Granules hepatitis B virus-associated primary liver cancer Pi(Spleen)-deficiency and dampness-heat syndrome 
Altered microbiota of rectal mucosa in rectal cancer patients
《World Journal of Gastroenterology》2025年第13期22-35,共14页Hao Zhang Yan Zhou You-Heng Jiang Wan-Ping Hu Lu-Lu Huang Hai-Xia Lin Zhi-Gui Zuo Ji-Mei Du Yong-Liang Lou 
Supported by the Medical and Health Research Project of Zhejiang Province,No.2023KY998.
BACKGROUND With advances in sequencing techniques,microbiota dysbiosis and pathogenic microbes that accelerate colorectal cancer progression have been identified and widely reported.However,few studies have focused on...
关键词：Rectal cancer Mucosal-associated microbiota Gut microbiota GENOMICS Predictive biomarkers 
Helicobacter pylori infection is linked to metabolic dysfunction and associated steatotic liver disease:A large cross-sectional study
《World Journal of Gastroenterology》2025年第13期79-88,共10页Lin Ye Kai Yan Ze Tian Zhi-Hua Xiao Ru-Yi Xie Zheng-Yuan Xie Li Tao 
Supported by Science and Technology Research Program of Jiangxi Provincial Department of Education,No.GJJ210225;2022 Provincial Health and Wellness Committee Science and Technology Program Projects,No.20221096;Jiangxi Provincial Natural Science Foundation's Young Scientists Fund,No.20242BAB20358.
BACKGROUND Helicobacter pylori(H.pylori),a globally widespread pathogen affecting half of the global population,has been increasingly implicated in metabolic disorders,including obesity,dyslipidemia,and metabolic dysf...
关键词：Helicobacter pylori OBESITY Blood glucose Lipid profile Blood pressure Metabolic dysfunction-associated steatotic liver disease 
Acid-sensing ion channel 1a promotes alcohol-associated liver disease in mice via regulating endoplasmic reticulum autophagy
《Acta Pharmacologica Sinica》2025年第4期989-1001,共13页Yue-qin Zhu Li-li Wang Zi-hao Li Shi-shun Qian Zhou Xu Jin Zhang Yong-hu Song Xue-sheng Pan Na Du Amira Abou-Elnour Lynn Jia Tay Jing-rong Zhang Meng-xue Li Yu-xian Shen Yan Huang 
supported by the National Natural Science Foundation of China(82370591);Key Project of the Joint Fund of the National Natural Science Foundation of China(U21A20345);the Fundamental Research Funds for the Central Universities(WK9110000197);the Anhui Province Higher Education Science Research Project(Natural Science)(2023AH040078);the Horizontal Project(H2023031);the 2021 Academic Funding Project for Top Talents in Higher Education Discipline(Major)(gxbjZD2021048);the 2023 Hefei Natural Science Foundation Project(2023018);the 2023 Anhui Medical University Research Level Improvement Plan Project(2023xkiT010);Pharmaceutical Peak Discipline Talent Fund Project“Research oriented Young Talents”(2023xkkq3);Anhui Province Excellent Research and Innovation Team Project(2024AH010013);the Anhui Medical University International Students Innovation Training Program Project(GJY202305;S202410366120);the 2023 New Era Education Provincial Quality Engineering Project Graduate Joint Training Demonstration Base[2023lhpysfjd023];the Early Contact Research Projects(2022-ZQKY-80;2023-YXYZQKY-40).
Alcohol-associated liver disease(ALD)is a hepatocyte dysfunction disease caused by chronic or excessive alcohol consumption,which can lead to extensive hepatocyte necrosis and even liver failure.Currently,the pathogen...
关键词：alcohol-associated liver disease ASIC1a Ca^(2+)influx ER-phagy ER stress apoptosis 
Rethinking carnitine palmitoyltransferase II and liver stem cells in metabolic dysfunction-associated fatty liver disease-related hepatocellular carcinoma
《World Journal of Gastroenterology》2025年第15期136-143,共8页Hong Cai Chun-Hui Yang Peng Gao 
This article discusses a recent study by Wang et al that sheds light on the metabolic and immunological mechanisms driving the progression of metabolic dysfunction-associated fatty liver disease(MAFLD)to hepatocellula...
关键词：Metabolic dysfunction-associated fatty liver disease Carnitine palmitoyltransferase II Hepatocellular carcinoma Liver cancer stem cells Mitochondrial dysfunction Metabolic dysfunction 
Associated network family of the unified piecewise linear chaotic family and their relevance
《Chinese Physics B》2025年第4期323-333,共11页Haoying Niu Jie Liu 
Duality analysis of time series and complex networks has been a frontier topic during the last several decades.According to some recent approaches in this direction,the intrinsic dynamics of typical nonlinear systems ...
关键词：nonlinear time series unified PWL chaotic family Lyapunov exponents complex network 
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