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ASSOCIATED: 作品数：1847被引量：4876H指数：24; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：范薇刘大伟隋丽华夏飞张萍更多>>; 相关机构：第二军医大学复旦大学北京大学中国科学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家高技术研究发展计划更多>>

Tale of mitochondria and mitochondria-associated ER membrane in patient-derived neuronal models of Wolfram syndrome: 《Neural Regeneration Research》2025年第9期2587-2588,共2页Laetitia Aubry Timothy Barrett Sovan Sarkar; supported by LifeArc Philanthropic Fund(P2019-0004);LifeArc Pathfinder Award;along with Wellcome Trust Seed Award(109626/Z/15/Z);FA PESP-UoB Strategic Collaboration Fund;Birmingham Fellowship(to SS);grants from Laboratoire d'Excellence Revive(Investissement d'Avenir;ANR-10-LABX-73);the Region lle-de-France via doctoral school Innovation Therapeutique,du Fondamentalàl'Appliqué(ED569)from Universite Paris-Saclay(to LA);Medical Research Council(MRC)Developmental Pathway Funding Scheme(DPFS)grant(MR/P007732/1)(to TB);supported by the Association Fran?aise contre les Myopathies(AFM-Téléthon)。; Mitochondria and mitochondria-associated endoplasmic reticulum membrane in neurodegenerative diseases:Mitochondria generate most of the chemical energy needed to power the biochemical reactions of cells,and thus are o...; 关键词：OXIDATIVE CYCLE carboxylic

Chronic hepatitis B triggering antineutrophil cytoplasmic antibodyassociated vasculitis complicated by glomerulonephritis:A case report: 《World Journal of Clinical Cases》2025年第19期43-51,共9页Ming-Ru Li Li-Ya Li Juan Tang Jian Sun; Supported by the Natural Science Foundation of Hunan Province,China,No.2023JJ30842.; BACKGROUND Hepatitis B virus(HBV)infection can lead to renal involvement,commonly manifested as HBV-associated glomerulonephritis(HBV-GN),which typically presents as nephrotic or nephritic syndrome.Antineutrophil cyto...; 关键词：Hepatitis B virus Antineutrophil cytoplasmic antibody-associated vasculitis NEPHROPATHY Complications Immune complex Alveolar hemorrhage Plasma exchange Protein A immunoadsorption Case report

Granulomatosis with polyangiitis induced by the anti-programmed cell death-1 inhibitor tislelizumab:A case report: 《World Journal of Clinical Cases》2025年第15期56-62,共7页Jian-Hui Zhao Jing-Jiao Wang Yi-Wen Li; BACKGROUND Immune checkpoint inhibitors(ICIs)are a new class of antitumor agents.They enhance antitumor effects by blocking inhibitory receptors and related ligands expressed on T cells.ICIs also modulate regular immu...; 关键词：Tislelizumab Programmed cell death-1 inhibitor Granulomatosis with polyangiitis Anti-neutrophil cytoplasmic antibody-associated vasculitis Case report

An assessment of atmospheric concentrations and spatiotemporal variation of BTEX and associated pollutants in India: 《Journal of Environmental Sciences》2025年第4期230-245,共16页Sruthi Jayaraj S.M.Shiva Nagendra; Benzene,toluene,ethylbenzene,and xylene(BTEX)pollution poses a serious threat to public health and the environment because of its respiratory and neurological effects,carcinogenic properties,and adverse effects on air...; 关键词：VOCS BTEX INDIA AQI Spatiotemporal variation

Novel oral compound Z526 mitigates cancer-associated cachexia via intervening NF-κB signaling and oxidative stress: 《Genes & Diseases》2025年第2期319-336,共18页Xiaofan Gu Shanshan Lu Shuang Xu Yiwei Li Meng Fan Guangyu Lin Yiyuan Liu Yun Zhao Weili Zhao Xuan Liu Xiaochun Dong Xiongwen Zhang; supported by the National Natural Science Foundation of China (No.82373317,82374085,82303818,22377087);the Science and Technology Commission of Shanghai Municipality,China (No.20S11902200,16DZ2280100);the Natural Science Foundation of Shanghai Municipality,China (No.23ZR1460500);the China Postdoctoral Science Foundation (No.2023M731106)。; Cancer-associated cachexia(CAC)is a severe metabolic disorder syndrome mainly characterized by muscle and fat loss,which accounts for one-third of cancer-related deaths.No effective therapeutic approach that could ful...; 关键词：Cancer-associated cachexia Fat lipolysis Muscle atrophy NF-κB signaling Oxidative stress Z526

Melatonin ameliorates Slc26a2-associated chondrodysplasias by attenuating endoplasmic reticulum stress and apoptosis of chondrocytes: 《Genes & Diseases》2025年第2期425-437,共13页Pan Li Chao Zheng Jingyan Hu Weiguang Lu Dong Wang Xue Hao Chengxiang Zhao Liu Yang Zhuojing Luo Qiang Jie; supported by the National Natural Science Foundation of China (No.82272442,82372361);the Key Industrial Chain Program of Shaanxi,China (No.2022ZDLSF02-12).; Although the pathogenesis and mechanism of congenital skeletal dysplasia are bet-ter understood,progress in drug development and intervention research remains limited.Here we report that melatonin treatment elicits a ...; 关键词：Ca^(2+)overload CHONDRODYSPLASIA Endoplasmic reticulum stress MELATONIN SLC26A2

Metabolic dysfunction-associated steatotic liver disease and omega- 6 polyunsaturated fatty acids: Friends or foes: 《World Journal of Hepatology》2025年第3期180-191,共12页Mona A Hegazy Safaa M Ahmed Shaimaa M Sultan Osama F Afifi Manal A Mohamed Alshimaa E Azab Mohamed A Hassanen Rakan K Zaben; BACKGROUND Metabolic dysfunction-associated steatotic liver disease(MASLD)is the most common chronic liver disease worldwide.Its prevalence is closely linked to the dramatic rise in obesity and non-communicable diseas...; 关键词：Metabolic dysfunction-associated steatotic liver disease Omega-6 polyunsaturated fatty acids Conjugated linoleic acid Arachidonic acid Lipid metabolism Oxidative stress STEATOHEPATITIS EICOSANOIDS

Effectiveness of CORDEX-AFRICA Multi-Model Ensemble in Replicating Temperature and Associated Extremes over Côte d’Ivoire: 《Atmospheric and Climate Sciences》2025年第1期147-174,共28页Assi Louis Martial Yapo Benjamin K. Kouassi Adjoua Moise Landry Famien Pêlèmayo Raoul Touré Fidèle Yoroba Dro Touré Tiemoko Kouakou Kouadio Mamadou Diarrassouba Dianikoura Ibrahim Koné Adama Diawara; Developing reliable adaptation and mitigation strategies to combat climate change is necessary at regional and local scales. The present study analyses the ability of the multi-model ensemble (MME) composed of fourtee...; 关键词：Extreme Temperature Indices Regional Climate Models Evaluation CORDEX Côte d’Ivoire

Investigation of the infection route of HIV-associated cytomegalovirus retinitis: 《International Journal of Ophthalmology(English edition)》2025年第3期478-486,共9页Jie Cai Zi-Kang Xie Dong-Yong Tang Hui-Yi Zuo Hao Liang; Supported by the Self-funded Research Project of the Health and Family Planning Commission of Guangxi Zhuang Autonomous Region(No.Z2016325).; AIM:To investigate the etiology of ocular pathogens and to establish the various pathogens present in human immunodeficiency virus(HIV)patients with cytomegalovirus retinitis(CMVR).METHODS:A total of 17 HIV-infected p...; 关键词：CYTOMEGALOVIRUS RETINITIS acquired immunodeficiency syndrome human immunodeficiency virus

Host preferences of root-associated fungi and their responses to decadal nitrogen and fungicide applications in an alpine pasture ecosystem: 《Journal of Integrative Agriculture》2025年第3期885-899,共15页Hao Xi Jing Zeng Jiayao Han Yali Zhang Jianbin Pan Qi Zhang Huyuan Feng Yongjun Liu; supported by the National Key Research and Development Program of China(2023YFF0805602);the National Natural Science Foundation of China(U21A20186,32171579,32371592 and 32471674);the Natural Science Foundation of Gansu Province,China(23JRRA1029 and 23JRRA1034)。; Plant roots interact with diverse fungi that are essential for maintaining the productivity and sustainability of pasture ecosystems,but how these root-associated fungi(RAF)differ between forage species and how they r...; 关键词：NITROGEN FUNGICIDE root-associated fungi host preference co-occurrence network plant–fungal interaction

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