funded by the National Natural Science Foundation of China(31902214);the earmarked fund for CARS(CARS-18);the National Key R&D Program of China(2022YFD1601908).
ATAD3A is a mitochondrial membrane protein belonging to the ATPase family that contains the AAA+domain.It is widely involved in mitochondrial metabolism,protein transport,cell growth,development and other important li...
supported by the Natural Science Foundation of Fujian Province,No.2020J02027;the National Natural Science Foundation of China,No.31970461;the Foundation of NHC Key Laboratory of Technical Evaluation of Fertility Regulation for Non-human Primate,Fujian Maternity and Child Health Hospital,No.2022-NHP-05(all to WC).
Certain amino acids changes in the human Na^(+)/K^(+)-ATPase pump,ATPase Na^(+)/K^(+)transporting subunit alpha 1(ATP1A1),cause Charcot-Marie-Tooth disease type 2(CMT2)disease and refractory seizures.To develop in viv...
supported by the National Natural Science Foundation of China,No.82173800 (to JB);Shenzhen Science and Technology Program,No.KQTD20200820113040070 (to JB)。
Na^(+)/K^(+)-ATPase is a transmembrane protein that has important roles in the maintenance of electrochemical gradients across cell membranes by transporting three Na^(+)out of and two K^(+)into cells.Additionally,Na^...
supported by the National Natural Science Foundation of China (22022707,22177142 and 22307108);Guangdong Basic and Applied Basic Research Foundation (2024B1515040028);the Fundamental Research Funds for the Central Universities.
Ruthenium polypyridyl complexes are promising anticancer candidates,while their cellular targets have rarely been identifed,which limits their clinical application.Herein,we design a series of Ru(II)polypyridyl comple...