supported by the National Natural Science Foundation of China,No.82371399(to YY);the Natural Science Foundation of Jiangsu Province,No.BK20221206(to YY);the Young Elite Scientists Sponsorship Program of Jiangsu Province,No.TJ-2022-028(to YY);the Scientific Research Program of Wuxi Health Commission,No.Z202302(to LY)。
Spontaneous recovery frequently proves maladaptive or insufficient because the plasticity of the injured adult mammalian central nervous system is limited.This limited plasticity serves as a primary barrier to functio...
Ultrasound has long been an essential tool in nephrology,traditionally used for procedures like vascular access and kidney biopsies.Point-of-care ultrasonography(POCUS),a rapidly evolving bedside technology,is now gai...
Cancer remains one of the leading causes of death in the world,with more than 9 million deaths in 2022,a number that continues to rise.This highlights the urgent need for the development of new drugs,with enhanced ant...
Non-occlusive mesenteric ischemia in critically ill patients still has a poor prognosis. Despite several established risk factors, the interaction between clinical conditions and perfusion mismatch often leads to prog...
Beijing Municipal Committee of Science and Technology(Z201100005620010);Chinese Academy of Medical Sciences clinical and translational medicine(2022-I2M C&T-B 116);Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(2019-I2M 5-029);Ministry of Finance of the People’s Republic of China(issued by Finance and Social Security(2015)Document No.82;(2016)Document No.50;(2017)Document No.72;(2018)Document No.48;(2019)Document No.77;(2020)Document No.75;(2021)Document No.84,Ministry of Finance and the National Key R&D Program of China(2022ZD0118005).
Background and purpose Acute vestibular syndrome(AVS)typically manifests as isolated dizziness or vertigo with no apparent neurological impairments.However,distinguishing life-threatening stroke from innocuous periphe...
Cover Story Autism spectrum disorder(ASD)is a complex neurodevelopmental condi-tion,characterized by social communication deficits,restrictive behaviors,and repetitive interests.Despite significant advances,the puzzle...
Background:Septic shock combined with septic cardiomyopathy greatly increases the risk of mortality in elderly patients.Patients with a rapid deteriorating state unresponsive to standard resuscitation may benefit from...
supported by the Medicine and Health Care in Zhejiang Province Science and Technology Plan Projects(Nos.2020KY552 and 2021PY006);the Commonweal Project of Science and Technology Department of Zhejiang Province(No.LGF21H030007),China.
Airborne transmission is among the most frequent types of nosocomial infection.Recent years have witnessed frequent outbreaks of airborne diseases,such as severe acute respiratory syndrome(SARS)in 2002,Middle East res...
Objective:To observe and analyze the application of the bedside rhetorical teaching method in teaching nursing interns.Methods:A total of 64 nursing interns in the gastroenterology department of our hospital from July...
supported by grants from the National Natural Science Foundation of China(82273948);High-level Innovative Research Institute(2021B0909050003);State Key Laboratory of Drug Research(SKLDR-2023-TT-01 and SIMM2205KF-09).
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most frequently mutated oncogene in human cancers with mutations predominantly occurring in codon 12. These mutations disrupt the normal function of KRAS by i...