supported by the National Key Research and Development Program of China(2021YFC2500300);the National Natural Science Foundation of China(81830005);Haihe Laboratory of Cell Ecosystem Innova-tion Fund(HH22KYZX0032);the Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(2020-I2M-C&T-A-019).
Dear Editor,Antigen escape is responsible for resistance[1]or disease relapse[2]from single-target chimeric antigen receptor(CAR)-T therapy.Dual-target CAR-T therapy has the potential to overcome the escape problem.Ho...