BACKGROUND To date,no specific treatment has been established to reverse progressive chronic kidney disease(CKD).AIM To evaluate the safety and efficacy of autologous CD34^(+)cell transplantation in CKD patients who e...
supported by the grants from the National Natural Science Foundation of China(Nos.81902801,82173729,82273833 and 82260031);the Program of Department of Natural Resources of Guangdong Province(No.GDNRC[2021]50);the Guangdong Provincial Key R&D Program(No.2022B1111070007);the Guangdong Basic and Applied Basic Research Foundation(No.2022A1515110620);the Science&Technology Program of Guangzhou City(No.20212210007);the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences(No.2019PT320005);the 2021 Central-Guided Local Science and Technology Development Fund(No.ZYYDDFFZZJ-1).
Umbilical cord blood(UCB)is an advantageous source for hematopoietic stem/progenitor cell(HSPC)transplantation,yet the current strategies for large-scale and cost-effective UCB-HSPC preparation are still unavailable.T...
BACKGROUND There is no established treatment to impede the progression or restore kidney function in human chronic kidney disease(CKD).AIM To examine the efficacy of cultured human CD34+cells with enhanced proliferati...
CD34+cells are multipotent hematopoietic stem cells also known as endothelial progenitor cells and are useful in regenerative medicine.Naturally,these cells are mobilized from the bone marrow into peripheral circulati...