Acute myeloid leukemia(AML) and its treatment have remained, for long, an area of slow but constant therapeutic progress as well as of permanent frustration. Chemotherapy has initially been and still is part of the ba...
from the clinical trial of CAR-T technique in the Treatment of Malignant Hematological Tumors registered on ClinicalTrials.gov(NCT05618041).
1.INTRODUCTION。CD7 is an ideal chimeric antigen receptor(CAR)target for T-cell acute lymphocytic leukemia(T-ALL).Donor-derived CAR-T-cell therapy,as an emerging treatment strategy,shows excellent efficacy in refracto...