CERAMIDE

作品数：96被引量：224H指数：7
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相关机构：复旦大学台北医学大学北京大学中国科学院更多>>
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Neurotensin-neurotensin receptor 2 signaling in adipocytes suppresses food intake through regulating ceramide metabolism
《Cell Research》2025年第2期117-131,共15页Wei Fu Yuanting Lai Kexin Li Yue Yang Xiao Guo Qifan Gong Xiaofeng Zhou Liying Zhou Cenxi Liu Zhi Zhang Jisun So Yufeng Zhang Lin Huang Guangxing Lu Chuanyou Yi Qichu Wang Chenyu Fan Chao Liu Jiaxing Wang Haiyi Yu Yimin Zhao Tao Huang Hyun Cheol Roh Tiemin Liu Huiru Tang Jianping Qi Ming Xu Yan Zheng He Huang Jin Li 
supported by the National Key R&D Program of China from Ministry of Science&Technology(2020YFA0803800,2019YFA0801900,NSFC92057115);Shanghai Sailing Program 20YF1402600 to H.H.,the National Key R&D Program of China from Ministry of Science&Technology(2020YFA0803600,2018YFA0801300,2023YFA1801000 to J.L.);the National Natural Science Foundation of China(32071138 and 32371193 to J.L.),and SKLGE-2118 to J.L.
Neurotensin(NTS)is a secretory peptide produced by lymphatic endothelial cells.Our previous study revealed that NTS suppressed the activity of brown adipose tissue via interactions with NTSR2.In the current study,we f...
关键词：INTAKE METABOLISM Together 
High doses of α-galactosylceramide potentiate experimental autoimmune encephalomyelitis by directly enhancing Th17 response被引量：3
《Cell Research》2010年第4期480-491,共12页Gaochao Qian Xia Qin Ying Qin Zang Baoxue Ge Taylor B Guo Bing Wan Lei Fang Jingwu Z Zhang 
α-Galactosylceramide （u-GC） is widely known to activate invariant natural killer T （iNKT） cells to suppress my- elin antigen-specific Thl responses, protecting susceptible mice against experimental antoimmune enc...
关键词：α-GC experimental autoimmune encephalomyelitis IL-17 
Transforming growth factor-β1 suppresses serum deprivation-induced apop-tosis via activation of ERK1/ERK2 and the inhibition of p38 activity and ceramide production
《Cell Research》2002年第3期298-298,共1页HEHUACHEN SHENGZHAO 等 
In this report we studied the effects and mechanism of transforming growth factor-β1 (TGF-β1) on serum deprivation-induced cell apoptosis. Serum deprivation induces apoptosis, which is associated with an increase in...
关键词：转化生长因子-β1 失血清诱发凋亡 抑制作用 ERK1/ERK2 活化 p38活性抑制 神经酰胺生成量 
The yins and yangs of ceramide
《Cell Research》1999年第1期1-10,共10页KAMAL SHARMA YUFANG SHI(Department of Immunology, Jerome H.Holland Laboratory, American Red Cross, 15601 Crabbs Branch Way,Rockville, MD 20855) 
Since their discovery over 100 years ago, sphingolipids have caught the eyes and the imagination of scientists.Modern science has made many new insights on the cell biology and day-to-day functions of many integral sp...
关键词：Cermide SPHINGOMYELINASE SIGNAL TRANSDUCTION 
High concentration of calcium ions in Golgi apparatus被引量：5
《Cell Research》1994年第1期97-108,共12页XUE SHAOBAI M. RoBERT NICOUD JIE CUI D.J.ARNDT JOVIN(Depariment of Biology, Beijing Normal University, Beijing 100875, China)(Max-Planck-Institute fur Biophysikalische Chemie,Gottingen, Germany) 
The interphase NIH3T3 cells were vitally fluorescentstained with calcium indicator fluo-3 and Glogi probe C6NBD-ceramide, and then the single cells were examined by laser scanning confocal microscopy (LSCFM) for subce...
关键词：intracellular free calcium fluo-3/AM Golgi apparatus C_6-NBD-ceramide laser scanning confocal microscopy intracellular calcium store 
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