云南高校图书馆联盟文献共享服务平台- CHOLESTASIS

CHOLESTASIS: 作品数：234被引量：1099H指数：16; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：丛林邢开周一鸣曹建彪马丽更多>>; 相关机构：上海交通大学医学院附属第九人民医院解放军261医院北京军区总医院杭州市余杭区第二人民医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金高等学校学科创新引智计划瑞士科学基金广东省自然科学基金更多>>

STING-mediated IL-6 Inhibits OATP1B1 Expression via the TCF4 Signaling Pathway in Cholestasis: 《Journal of Clinical and Translational Hepatology》2024年第8期701-712,共12页Yan Guo Hongjia Zhang Nan Zhao Ying Peng Dongya Shen Yubin Chen Xiaoxun Zhang Can-E Tang Jin Chai; supported by grants from the National Natural Science Foundation of China(82325008,81974112,and 82370642);the Natural Science Foundation of Hunan Province(2024JJ5611);the Outstanding Medical Research Group of Chongqing(414Z381).; Background and Aims Organic anion-transporting polypeptides(OATPs)play a crucial role in the transport of bile acids and bilirubin.In our previous study,interleukin 6(IL-6)reduced OATP1B3 levels in cholestatic disease...; 关键词：Inflammation Bile acid BILIRUBIN CHOLESTASIS STING IL-6 β-catenin TCF4

Heritable Chronic Cholestatic Liver Diseases:A Review: 《Journal of Clinical and Translational Hepatology》2024年第8期726-738,共13页Jasmine Tidwell George Y.Wu; Chronic cholestasis due to heritable causes is usually diagnosedin childhood.However,many cases can present andsurvive into adulthood.The time course varies considerablydepending on the underlying etiology.Laboratory ...; 关键词：Chronic cholestasis Cholestatic liver disease Congenital hepatic fibrosis Caroli disease Caroli syndrome Alagille syndrome Biliary atresia

Late-onset Cholestasis with Paucity of Portal Area Secondary: 《Journal of Clinical and Translational Hepatology》2024年第3期327-331,共5页Xuemei Zhang Kun Liu Xiaona Lu Wenlan Zheng Jia Shi Shihan Yu Hai Feng Zhuo Yu; supported by National Natural Science Foun-dation of China(Nos.82222074,82074154,81774240);Siming Scholar from Shanghai Shuguang Hospital(No.SGXZ-201904);Shuguang Program of Shanghai Education Development Foundation and Shanghai Municipal Education Commission,Youth Tip-top Talent Program,Constant-emi-nent Program in Shanghai,Xinglin Youth Scholar Program from Shanghai University of Traditional Chinese Medicine.; Hepatocyte nuclear factor 1β(HNF1β)is essential for biliary development,while its genetic defect triggers the dysplasia of interlobular bile ducts,leading to life-threatening hepatitis and cholestasis.To date,this d...; 关键词：HNF1β CHOLESTASIS Adult patient Paucity of the portal area Renal cysts Case report

Histopathological Features Predicting Long-term Clinical Outcomes in Patients with Vanishing Bile Duct Syndrome被引量：1: 《Journal of Clinical and Translational Hepatology》2023年第5期1161-1169,共9页Tingting Lv Haitian Yu Xiao Han Aileen Wee Jimin Liu Min Li Jinghang Xu Xiaoli Hu Jia Li Weijia Duan Tailing Wang Jidong Jia Xinyan Zhao; supported by National Natural Science Foundation of China(No.82100633 to LTT).; Background and Aims:The clinicopathological features and long-term outcomes of patients with vanishing bile duct syndrome(VBDS)have yet to be elucidated.The study aims to investigate these features and identify factor...; 关键词：Bile duct loss PROGNOSIS CHOLESTASIS Foam cells Advanced fibrosis

Neonatal Dubin-Johnson Syndrome and its Differentiation from Biliary Atresia: 《Journal of Clinical and Translational Hepatology》2023年第1期163-173,共11页Teng Liu Jing Zhao Jia-Yan Feng Yi Lu Jonathan A.Sheps Ren-Xue Wang Jun Han Victor Ling Jian-She Wang; funded by the National Natural Science Foundation of China,Grants Number 81873543 and 82171853 (to JSW);supported by the Shanghai Sailing Program (20YF1402900 to TL);Chan-Xue Yan Program of Fudan University (FDEKCXY17 to TL);Canadian Institutes of Health Research (to VL&RW);support from The Metabolomics Innovation Center through the Genome Innovations Network,and from Genome Canada,Genome BC,and Genome Alberta for operations (205MET and 7203);technology development (215MET and MC3T).; Background and Aims:The aim was to determine if liver biochemistry indices can be used as biomarkers to help differentiate patients with neonatal Dubin–Johnson syndrome(nDJS)from those with biliary atresia(BA).Method...; 关键词：JAUNDICE ABCC2 CHOLESTASIS MRP2 Acholic stools

Selective Androgen Receptor Modulators:An Emerging Liver Toxin被引量：2: 《Journal of Clinical and Translational Hepatology》2023年第1期188-196,共9页Haseeb Mohideen Hafsa Hussain Dushyant Singh Dahiya Hisham Wehbe; Selective androgen receptor modulators(SARMs)are a class of nonsteroidal drugs that are favored over anabolic androgenic steroids(AASs)for their tissue-selectivity and improved side-effect profile.These drugs have bee...; 关键词：Drug-induced liver injury Androgen receptor agonist CHOLESTASIS Anabolic steroids

A Multipathogen Bile Sample-based PCR Assay Can Guide Empirical Antimicrobial Strategies in Cholestatic Liver Diseases被引量：1: 《Journal of Clinical and Translational Hepatology》2022年第5期788-795,共8页Michael Jahn Mustafa KÖzçürümez Sebastian Dolff Hana Rohn Dominik Heider Alexander Dechêne Ali Canbay Peter M.Rath Antonios Katsounas; support by the Open Access Publication Fund of the University of Duisburg-Essen.; Background and objectives:Polymerase chain reaction(PCR)techniques provide rapid detection of pathogens.This pilot study evaluated the diagnostic utility and clinical impact of multiplex real-time PCR(mRT-PCR,SeptiFas...; 关键词：ERCP PCR Antibiotic prophylaxis CHOLESTASIS CHOLANGITIS

Statin-induced Liver Injury Patterns: A Clinical Review被引量：3: 《Journal of Clinical and Translational Hepatology》2022年第3期543-552,共10页Leon D.Averbukh Alla Turshudzhyan David C.Wu George Y.Wu; Since their introduction in 1987,hydroxymethyl glutaryl coenzyme A reductase(HMG-CoA)inhibitors,more commonly known as statins,have become some of the most widely prescribed medications in the world.Though generally c...; 关键词：Drug-induced liver injury STATIN Cholestatic liver injury Hepatocellular liver injury CHOLESTASIS Autoimmune hepatitis

Mechanisms of Hepatic Cholestatic Drug Injury被引量：7: 《Journal of Clinical and Translational Hepatology》2019年第1期86-92,共7页Tea Omanovic Kolaric Vjera Nincevic Robert Smolic Martina Smolic George Y Wu; Drug-induced cholestasis represents a form of drug-induced liver disease that can lead to severe impairment of liver function.Numerous drugs have been shown to cause cholestasis and consequently bile duct toxicity.How...; 关键词：Drug-induced liver injury Bile acids CHOLESTASIS

Therapeutic Roles of Bile Acid Signaling in Chronic Liver Diseases被引量：3: 《Journal of Clinical and Translational Hepatology》2018年第4期425-430,共6页Yan Li Lun-Gen Lu; Bile acids(BAs)are the major metabolic product of cholesterol,having detergent-like activities and being responsible for absorption of lipid and lipid-soluble vitamins.Tn addition,it has been increasingly recognized t...; 关键词：BAS CHOLESTASIS Chronic liver diseases FXR TGR5

CHOLESTASIS