Multidrug Resistance Protein 2 (MRP2) is an ATP-dependent transmembrane protein that plays a pivotal role in the efflux of a wide variety of physiological substrates across the plasma membrane. Several studies have sh...
funded by the National Natural Science Foundation of China,Grants Number 81873543 and 82171853 (to JSW);supported by the Shanghai Sailing Program (20YF1402900 to TL);Chan-Xue Yan Program of Fudan University (FDEKCXY17 to TL);Canadian Institutes of Health Research (to VL&RW);support from The Metabolomics Innovation Center through the Genome Innovations Network,and from Genome Canada,Genome BC,and Genome Alberta for operations (205MET and 7203);technology development (215MET and MC3T).
Background and Aims:The aim was to determine if liver biochemistry indices can be used as biomarkers to help differentiate patients with neonatal Dubin–Johnson syndrome(nDJS)from those with biliary atresia(BA).Method...
Aim:This study investigated the ATP binding cassette(ABC)transporter(ABCA1,ABCB1,ABCB3,ABCC2 and ABCG2)expression in high grade serous ovarian cancer(HGSOC)tissues,cell lines and primary cells to determine their poten...
supported by the Key Project for Breeding Genetic Modified Organisms of China(2016ZX08012004003)。
ATP-binding cassette transporter C2(ABCC2)is known to be a receptor for Bacillus thuringiensis(Bt)toxins in several lepidopteran insects.Mutations in the ABCC2 gene have been genetically linked to field-evolved resist...