CLOPIDOGREL

作品数:154被引量:581H指数:15
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相关领域:医药卫生更多>>
相关作者:邹建军邱声强张冰胡正刚王庄更多>>
相关机构:南京医科大学中国药科大学湖州市中心医院太原市中心医院更多>>
相关期刊:更多>>
相关基金:国家自然科学基金国家科技支撑计划国家重点基础研究发展计划河北省自然科学基金更多>>
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  • 期刊=Chinese Medical Journalx
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In-hospital outcomes of anemic patients with acute coronary syndrome receiving ticagrelor versus clopidogrel: Results of the Chinese Cardiovascular Care Improvement (CCC)-Acute Coronary Syndrome Project
《Chinese Medical Journal》2024年第20期2489-2491,共3页Zhiqiang Zhang Yasong Wang Jun Wang Xiaofan Cao Miaohan Qiu Xiaoxiang Tian Yaling Han Xiaozeng Wang 
This study was supported by the China National Key R&D Project (contract No. 2022YFC2503500);The CCC-ACS project is a program of the AHA and the CSC. The AHA received funding from Pfizer through an independent grant for learning and change and Astra-Zeneca as a quality improvement initiative.
To the Editor:Dual antiplatelet therapy(DAPT),which comprises aspirin plus a P2Y12 receptor inhibitor,is the standard approach for reducing cardiac and systemic ischemic events in individuals with coronary artery dise...
关键词:coronary PATIENTS BLEEDING 
Safety of early surgery for geriatric hip fracture patients taking clopidogrel:a retrospective case-control study of 120 patients in China被引量:3
《Chinese Medical Journal》2021年第14期1720-1725,共6页Ming-Hui Yang Bo Li Dong-Chen Yao Yan Zhou Wen-Chao Zhang Geng Wang Ping Zhang Shi-Wen Zhu Xin-Bao Wu 
the Capital’s Funds for Health Improvement and Research(No.2018-1-2071);the National Natural Science Foundation of China(No.82072445).
Background:Geriatric hip fracture patients receiving clopidogrel are a surgical challenge.In China,most of these patients undergo delayed surgical treatment after clopidogrel withdrawal for at least 5 to 7 days.Howeve...
关键词:Hip fracture CLOPIDOGREL Blood loss Blood transfusion COMPLICATION Mortality 
Efficacy and safety of potent P2Y12 inhibitors vs.clopidogrel in elderly patients with acute coronary syndrome
《Chinese Medical Journal》2020年第21期2628-2629,共2页Li-Man Luo Zhan-Qi Pang Meng-Lu Fu Yuan-Yuan Li Ling Tu Xi-Zhen Xu 
the grants from the National Natural Science Foundation of China(No.81471021 and No.81873512);the Hu Bei Health and Family Planning Commission(No.WJ2015MB006)。
To the Editor:Current guidelines recommended that patients with acute coronary syndrome(ACS)should receive dual anti-platelet therapy of aspirin plus P2Y12 inhibitors(clopidogrel,prasugrel,or ticagrelor)if without con...
关键词:PATIENTS sided ELDERLY 
Optimal strategy of switching from clopidogrel to ticagrelor in Chinese acute coronary syndrome patients with complicated coronary artery disease: the switching from clopidogrel to ticagrelor (SHIFT-CACS) study被引量:2
《Chinese Medical Journal》2019年第19期2292-2299,共8页Ying Yao Ping Wang Xiao-Zeng Wang Xin Zhao Wei Zhao Tie-Nan Zhou Lei Zhang 
Background:The dose and time point for switching from clopidogrel to ticagrelor remain controversial,especially for Chinese acute coronary syndrome(ACS)patients with complicated coronary artery disease(CAD).Hence,the ...
关键词:CLOPIDOGREL Drug SUBSTITUTION PHARMACOLOGY Ticagrelor 
Clinical outcomes and predictive model of platelet reactivity to clopidogrel after acute ischemic vascular events被引量:3
《Chinese Medical Journal》2019年第9期1053-1062,共10页Qi Ma Guang-Zhong Chen Yu-Hu Zhang Li Zhang Li-An Huang 
Background:High on-treatment platelet reactivity (HTPR) has been suggested as a risk factor for patients with ischemic vascular disease.We explored a predictive model of platelet reactivity to clopidogrel and the rela...
关键词:High on-treatment PLATELET reactivity CLOPIDOGREL CYP2C19 Light TRANSMITTANCE AGGREGOMETRY ISCHEMIC vascular events 
De-escalation of anti-platelet therapy in patients with acute coronary syndromes undergoing percutaneous coronary intervention: a narrative review被引量:19
《Chinese Medical Journal》2019年第2期197-210,共14页Ya-Ling Han 
Objective:Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor inhibitor is the cornerstone of treatment in patients with acute coronary syndromes (ACS) and in those undergoing percutaneous coronary inte...
关键词:Acute CORONARY SYNDROME ANTIPLATELET therapy CLOPIDOGREL DE-ESCALATION Ticagrelor 
Impact of Baseline Bleeding Risk on Efficacy and Safety of Ticagrelor versus Clopidogrel in Chinese Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention被引量:17
《Chinese Medical Journal》2018年第17期2017-2024,共8页He-Yang Wang Yi Li Xiao-Ming Xu Jing Li Ya-Ling Han 
Background: There was still conflict on the antithrombotic advantage of ticagrelor versus clopidogrel among East Asian population with acute coronary syndrome (ACS). We considered that the baseline bleeding risk mi...
关键词:Baseline Bleeding Risk: Clopidogrel Crusade Score: Efficacy: Ticagrelor 
Impact of Proton-pump Inhibitors on the Pharmacodynamic Effect and Clinical Outcomes in Patients Receiving Dual Antiplatelet Therapy after Percutaneous Coronary Intervention: A Propensity Score Analysis被引量:8
《Chinese Medical Journal》2017年第24期2899-2905,共7页Pei Zhu Zhan Gao Xiao-Fang Tang Jing-Jing Xu Yin Zhang Li-Jian Gao Jue Chen Shu-Bin Qiao Yue-Jin Yang Run-Lin Gao Bo Xu Jin-Qing Yuan 
This study was supported by grants from the National Natural Science Foundation of China (No. 81470486), and the National Key Research and Development Program of China during the 13^th 5-Year Plan Period (No. 2016YFC1301301).
Background:Prior studies have reported controversial conclusions regarding the risk of adverse cardiovascular events in patients using proton-pump inhibitors (PPIs) combined with clopidogrel therapy,causing much un...
关键词:CLOPIDOGREL Drug Interactions Percutaneous Coronary Intervention Proton-pump lnhibitors 
Head to Head Comparison of Two Point-of-care Platelet Function Tests Used for Assessment of On-clopidogrel Platelet Reactivity in Chinese Acute Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention被引量:8
《Chinese Medical Journal》2016年第19期2269-2274,共6页Yi Yao Jia-Hui Zhang Xiao-Fang Tang Chen He Yuan-Liang Ma Jing-Jing Xu Ying Song Ru Liu Xian-Min Meng Lei Song Miao Wang Run-Lin Gao Jin-Qing Yuan 
This study was supported by a grant from the National Natural Science Foundation of China (No. 81470486).
Background:Platelet function tests are widely used in clinical practice to guide personalized antiplatelet therapy.In China,the thromboelastography (TEG) test has been well accepted in clinics,whereas VerifyNow,mai...
关键词:Blood Platelets CLOPIDOGREL THROMBOELASTOGRAPHY VerifyNow 
Efficacy of Leflunomide, Telmisartan, and Clopidogrel for Immunoglobulin A Nephropathy: A Randomized Controlled Trial被引量:13
《Chinese Medical Journal》2016年第16期1894-1903,共10页Jie Wu Shu-Wei Duan Xue-Feng Sun Wen-Ge Li Ya-Ping Wang Wen-Hu Liu Jian-Rong Zhang Li-De Lun Xue-Mei Li Chun-Hua Zhou Ji-Jun Li Shu-Wen Liu Yuan-Sheng Xie Guang-Yan Cai Lu Ma Wen Huang Hua Wu Qiang Jia Xiang-Mei Chen 
Background: The efficacy and safety of telmisartan combined with clopidogrel, leflunomide, or both drugs for immunoglobulin A nephropathy (IgAN) are unclear. This study was designed to evaluate the efficacy and saf...
关键词:CLOPIDOGREL Immunoglobulin A Nephropathy LEFLUNOMIDE Randomized Controlled Trial 
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