This study was supported by the China National Key R&D Project (contract No. 2022YFC2503500);The CCC-ACS project is a program of the AHA and the CSC. The AHA received funding from Pfizer through an independent grant for learning and change and Astra-Zeneca as a quality improvement initiative.
To the Editor:Dual antiplatelet therapy(DAPT),which comprises aspirin plus a P2Y12 receptor inhibitor,is the standard approach for reducing cardiac and systemic ischemic events in individuals with coronary artery dise...
the Capital’s Funds for Health Improvement and Research(No.2018-1-2071);the National Natural Science Foundation of China(No.82072445).
Background:Geriatric hip fracture patients receiving clopidogrel are a surgical challenge.In China,most of these patients undergo delayed surgical treatment after clopidogrel withdrawal for at least 5 to 7 days.Howeve...
the grants from the National Natural Science Foundation of China(No.81471021 and No.81873512);the Hu Bei Health and Family Planning Commission(No.WJ2015MB006)。
To the Editor:Current guidelines recommended that patients with acute coronary syndrome(ACS)should receive dual anti-platelet therapy of aspirin plus P2Y12 inhibitors(clopidogrel,prasugrel,or ticagrelor)if without con...
Background:The dose and time point for switching from clopidogrel to ticagrelor remain controversial,especially for Chinese acute coronary syndrome(ACS)patients with complicated coronary artery disease(CAD).Hence,the ...
Background:High on-treatment platelet reactivity (HTPR) has been suggested as a risk factor for patients with ischemic vascular disease.We explored a predictive model of platelet reactivity to clopidogrel and the rela...
Objective:Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor inhibitor is the cornerstone of treatment in patients with acute coronary syndromes (ACS) and in those undergoing percutaneous coronary inte...
Background: There was still conflict on the antithrombotic advantage of ticagrelor versus clopidogrel among East Asian population with acute coronary syndrome (ACS). We considered that the baseline bleeding risk mi...
This study was supported by grants from the National Natural Science Foundation of China (No. 81470486), and the National Key Research and Development Program of China during the 13^th 5-Year Plan Period (No. 2016YFC1301301).
Background:Prior studies have reported controversial conclusions regarding the risk of adverse cardiovascular events in patients using proton-pump inhibitors (PPIs) combined with clopidogrel therapy,causing much un...
This study was supported by a grant from the National Natural Science Foundation of China (No. 81470486).
Background:Platelet function tests are widely used in clinical practice to guide personalized antiplatelet therapy.In China,the thromboelastography (TEG) test has been well accepted in clinics,whereas VerifyNow,mai...
Background: The efficacy and safety of telmisartan combined with clopidogrel, leflunomide, or both drugs for immunoglobulin A nephropathy (IgAN) are unclear. This study was designed to evaluate the efficacy and saf...