With the improved detection sensitivity and diagnostic accuracy,circulating tumor DNA(ctDNA)has emerged as a highly valuable biomarker in precision oncology for colorectal cancer(CRC).ctDNA has been well established a...
BACKGROUND Colorectal anastomotic leakage(CAL),a severe postoperative complication,is associated with high morbidity,hospital readmission,and overall healthcare costs.Early detection of CAL remains a challenge in clin...
This work was supported in part by grant NIH-R01CA/DK80982-01 from the National Institutes of Health and a grant the FAMRI.
Background:Despite considerable advances in preoperative imaging,up to one-third of patients operatively explored for hepatic colorectal metastases are unexpectedly found to harbor unresectable intrahepatic or extrahe...
Supported by the Ministry of Health–Incentive Program for the Integration of Care and Valuation of Patients’ Pathways in the National Health Service of Portugal
BACKGROUND Colorectal anastomotic leakage(CAL)is one of the most dreaded complications after colorectal surgery,with an incidence that can be as high as 27%.This event is associated with increased morbidity and mortal...
Background: Fast track surgery is an evidence-based multidisciplinary approach. The underlying principle is to enable patients to recover from surgery and leave the hospital sooner by minimizing the stress responses o...
Introduction: Lymph node (LN) metastasis are important biomarkers in the resection of colorectal cancer translating into accurate disease staging. It is therefore obvious that lymph node dissection in the curative tre...
The concept of enhanced recovery after surgery(ERAS)has been established in adult surgery since the 1990s,starting with Kehlet’s studies on colorectal surgery.ERAS is based on the premise that patient postoperative o...
Objective: The purpose of this study was to observe the factors related to T4 patients who underwent surgery for colorectal cancer (CRC) with peritoneal carcinomatosis. Methods: 154 T...
Introduction Liver surgery for colorectal liver metastasis(CRLM)has evolved considerably over the past two decades.Novel chemotherapy regimens and effective targeted therapy,changes in the view of resectability criter...
Objective: To retrospectively analyze the prognostic differences between LCC and RCC, and to explore the occurrence of such differences in the relevant factors. Provide clinical basis for the individu...