CYTOPLASMIC

作品数：229被引量：700H指数：12
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Cytoplasmic and nuclear programmed death ligand 1 expression in peritumoral stromal cells in breast cancer:Prognostic and predictive value
《World Journal of Experimental Medicine》2025年第2期150-170,共21页Evgeniya Yu Zubareva Marina A Senchukova Natalia V Saidler 
Supported by Russian Science Foundation,No.23-25-00183.
BACKGROUND Breast cancer(BC)continues to occupy a leading position in terms of morbidity and mortality from malignant neoplasms among the female population.One of the promising markers associated with BC progression i...
关键词：Breast cancer Programmed death-ligand 1 Regional metastasis Tumor stroma 
Anti-nuclear cytoplasmic antibody-associated vasculitis and kidney cancer:A mini review
《World Journal of Nephrology》2025年第2期27-33,共7页Samuel Wilding Henry H L Wu Nina Brown Rajkumar Chinnadurai 
This mini review explores the links between anti-neutrophil cytoplasmic antibody-associated vasculitis(AAV)and kidney cancer.Several studies suggest an increased incidence of cancer for patients with AAV.Different can...
关键词：Anti-nuclear cytoplasmic antibody-associated vasculitis Kidney cancer Etiology Pathophysiology Immunosuppression 
SNX3 mediates heart failure by interacting with HMGB1 and subsequently facilitating its nuclear-cytoplasmic translocation
《Acta Pharmacologica Sinica》2025年第4期964-975,共12页Hong Li Ming-xia Peng Rui-xue Yang Jian-xing Chen Yue-mei Wang Pan-xia Wang Yue-huai Hu Di-yi Pan Pei-qing Liu Jing Lu 
supported by the National Natural Science Foundation of China(82473914,82173808,U21A20419,81903606);Guangzhou Basic and Applied Basic Research Project(2024A04J10013,202102021272);Guangdong Provincial Key Laboratory of Construction Foundation(2017B030314030);Traditional Chinese Medicine Bureau of Guangdong Province(20231134,20231158).
Sorting nexins(SNXs)as the key regulators of sorting cargo proteins are involved in diverse diseases.SNXs can form the specific reverse vesicle transport complex(SNXs-retromer)with vacuolar protein sortings(VPSs)to so...
关键词：heart failure cardiac hypertrophy SNX3 HMGB1 RETROMER ISOPROTERENOL 
Fortify the defense frontline:MAPKs phosphorylate receptor-like cytoplasmic kinase to maintain plant resistance in soybean
《Stress Biology》2024年第1期486-489,共4页Lu Rui Wei Wang 
supported by the Science and Technology Research Program of Chongqing Municipal Education Commission(Grant No.KJQN202201225 to L.R.);the Open Fund of Fujian Provincial Key Laboratory of Eco-Industrial Green Technology(Grant No.WYKF-EIGT2022-6 to L.R.);the National Natural Science Foundation of China(Grant No.32370302 to W.W.).
Mitogen-activated protein kinase(MAPK)activation is one of the significant immune events that respond to pathogens in plants.A MAPK cascade often contains a MAPK kinase kinase(MAPKKK),a MAPK kinase(MAPKK/MKK),and a MA...
关键词：Plant immunity SOYBEAN Nematode Mitogen-activated protein kinase(MAPK) Receptor-like cytoplasmic kinase(RLCK) 
The receptor-like cytoplasmic kinase OsBSK1-2 regulates immunity via an HLH/bHLH complex
《Journal of Integrative Plant Biology》2024年第12期2754-2771,共18页Xun Wang Zhijuan Diao Chang Cao Yan Liu Na Xia Youlian Zhang Ling Lu Fanyu Kong Houli Zhou Lizhe Chen Jing Zhang Bangsheng Wang Ronghua Huang Dingzhong Tang Shengping Li 
supported by National Key Research and Development Program of China (2022YFF1001500);Guiding Project of Fujian Science and Technology Plan(2022N0005)
Plants need to fine-tune defense responses to maintain a robust but flexible host barrier to various pathogens.Helix-loop-helix/basic helix-loop-helix(HLH/bHLH)complexes play important roles in fine-tuning plant devel...
关键词：Magnaporthe oryzae OsbHLH6 OsBSK1-2 OsHLH46 rice rice blast resistance RLCK 
The symphony of maize signaling quartet defending against gray leaf spot
《Stress Biology》2024年第1期543-546,共4页Ping Wang Ping He 
support from the National Natural Science Foundation of China(32302370 to P.W.);USDA NIFA(grant 2020-67013-31615 to P.H.).
In plant immunity,a well-orchestrated cascade is initiated by the dimerization of receptor-like kinases(RLKs),followed by the phosphorylation of receptor-like cytoplasmic kinases(RLCKs)and subsequent activation of NAD...
关键词：Receptor-like kinases Receptor-like cytoplasmic kinases NADPH oxidase Grey leaf spot Pattern-triggered immunity 
Synergy in Rice Immunity:Exploring Strategies of Coordinated Disease Defense Through Receptor-Like Kinases and Receptor-Like Cytoplasmic Kinases
《Rice science》2024年第6期643-658,共16页PEI Mengtian CAO Yingying XIE Xuze CAO Ying CHEN Jia ZHANG Xi WANG Zonghua LU Guodong ZHANG Shenghang 
supported by the National Natural Science Foundation of China (Grant No.U2005211);the Fuzhou General Teaching Hospital (the 900th Hospital)Key Project,China (Grant No.2022ZD01);the Fujian Clinical Research Center for Aptamer-based Precision Testing,China (Grant No.2021Y2017)。
Receptor-like kinases(RLKs)and receptor-like cytoplasmic kinases(RLCKs)play an indispensable role in the perception and transmission of extracellular signals in plants.In rice,these kinases actively participate in imm...
关键词：receptor-like kinase receptor-like cytoplasmic kinase pathogen-associated molecular pattern genetic breeding 
Potential regulatory mechanism and clinical significance of synaptotagmin binding cytoplasmic RNA interacting protein in colorectal cancer
《World Journal of Clinical Oncology》2024年第11期1412-1427,共16页Hui Li He-Qing Huang Zhi-Guang Huang Rong-Quan He Ye-Ying Fang Rui Song Jia-Yuan Luo Da-Tong Zeng Kai Qin Dan-Ming Wei Gang Chen 
Supported by Guangxi Zhuang Autonomous Region Health Commission Scientific Research Project,No.Z-A20220415 and No.Z20210442;The First Affiliated Hospital of Guangxi Medical University Provincial and Ministerial Key Laboratory Cultivation Project:Guangxi Laboratory of Enhanced Recovery after Surgery for Gastrointestinal Cancer,No.21-220-18.
BACKGROUND Colorectal cancer(CRC)causes many deaths worldwide.Synaptotagmin binding cytoplasmic RNA interacting protein(SYNCRIP)is an RNA-binding protein that plays an important role in multiple cancers by epigenetica...
关键词：Synaptotagmin binding cytoplasmic RNA interacting protein Colorectal cancer Radiotherapy Cell mitosis Immune microenvironment 
Effects on Synaptic Plasticity Markers in Fetal Mice and HT22 Neurons upon F‑53B Exposure:The Role of PKA Cytoplasmic Retention
《Environment & Health》2024年第11期776-785,共10页Shen-Pan Li Hui-Xian Zeng Shuang-Jian Qin Qing-Qing Li Lu-Yin Wu Qi-Zhen Wu Li-Zi Lin Guang-Hui Dong Xiao-Wen Zeng 
supported by the National Science Foundation of China(No.82073503,82173471,82003409,82103823);the Natural Science Foundation of Guangdong Province(No.2021B1515020015,2021A1515012212);the Guangzhou Science and Technology Plan Project(No.2024A04J6476).
Chlorinated polyfluorinated ether sulfonate(F-53B),a chromium-fog depressant widely utilized as an alternative to perfluorooctanesulfonate,can transfer from mother to fetus.Recent research has demonstrated that prenat...
关键词：F-53B Synaptic plasticity PKA/CREB signaling pathway Early neurotoxicity PKA cytoplasmic retention 
New therapeutic target NCF1-directed multi-bioactive conjugate therapies prevent preterm birth and adverse pregnancy outcomes
《Science Bulletin》2024年第16期2604-2621,共18页Juan Cheng Xiaoyan Jia Limei Yang Siqi Zhang Zhiyu Chen Qian Gui Ting Li Zedan Pu Hongbo Qi Jianxiang Zhang 
supported by the National Natural Science Foundation of China(82301918);Joint Funds of the National Natural Science Foundation of China(U21A20346);the Natural Science Foundation of Chongqing(CSTB2022NSCQ-MSX0856);the Key Program for Technological Innovation&Application Development of Chongqing(CSTB2022TIAD-KPX0156);the Key Medical Program Integrated by Chongqing Science and Technology Bureau and Chongqing Health Commission(2023GGXM005);the Program for Scientific and Technological Innovation Leader of Chongqing(CQYC20210302362).
Preterm birth(PTB)is a leading cause of neonatal morbidity and mortality worldwide,yet the cellular and molecular mechanisms driving this condition remain undeciphered,thus limiting discovery of new therapies.In-depth...
关键词：Preterm birth Neutrophil cytoplasmic factor Bioactive conjugate Nanotherapy Hydrogel therapy 
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