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Fructose aggravating colon barrier dysfunction by decreasing gut bacteria metabolites indole-3-carboxaldehyde and inhibiting activation of aryl hydrocarbon receptor in vivo and in vitro
《Food Science and Human Wellness》2025年第4期1480-1497,共18页Ge Song Shaojie Pang Wenting Peng Wei Fang Yong Wang Rui Liu Qianyun Gan Wentao Qi 
supported by the Special Funds of Basic Research of Central Public Welfare Institute(JY2010 and ZX2410)。
Background:Fructose may induce non-alcoholic fatty acids(NAFLD)due to the gut-liver axis interactions.The mechanism of fructose impairing colon barrier is unrevealed.Methods:Normal and dextran sulfate sodium(DSS)-indu...
关键词：FRUCTOSE Tryptophan metabolites Colon barrier 
The combination of SLC7A11 inhibitor and oridonin synergistically inhibits cervical cancer cell growth by decreasing the NADPH/NADP+ratio
《Genes & Diseases》2025年第1期137-140,共4页Yajie Liu Pengxing He Xubin Ma Yingqi Tian Yu Zhang Yang Wang Yingjie Jia Hongmin Liu Ying Liu Yichao Xu 
supported by the National Key Research and Development Project(China)(No.2018YFE0195100);the National Natural Science Foundation of China(No.82020108030);the Key Scientific Research Projects in Colleges and Universities of Henan Province,China(No.23A350007).
SLC7A11,as the core component of system xc,protects cancer cells from oxidative-stress-induced cell death like ferroptosis by mediating cystine uptake.Recent studies revealed that SLC7A11 is widely overexpressed in va...
关键词：CERVICAL HERBAL synergistic 
Glial growth factor 2 treatment alleviates ischemia and reperfusion-damaged integrity of the blood-brain barrier through decreasing Mfsd2a/caveolin-1-mediated transcellular and Pdlim5/YAP/TAZ-mediated paracellular permeability被引量：1
《Acta Pharmacologica Sinica》2024年第11期2241-2252,共12页Xiao-ling Zhang Wei-hong Du Shu-xia Qian Xu-dong Lu Xin Yu Hai-lun Fang Jia-li Dong Min Song Yan-yun Sun Xiao-qiang Wu Yu-fei Shen Ya-nan Hao Min-hui Shen Bei-qun Zhou Yan-ping Wang Cong-ying Xu Xin-chun Jin 
supported by Zhejiang Provincial Natural Science Foundation of China(LTGY24H090002);the Medical and Health Science and Technology Plan Project of Zhejiang Province(2024KY1685);Jiaxing Plan of Science and Technology(2022AY30028);supported by by National Natural Science Foundation of China(81870973,81671145).
The impairment of blood-brain barrier(BBB)integrity is the pathological basis of hemorrhage transformation and vasogenic edema following thrombolysis and endovascular therapy.There is no approved drug in the clinic to...
关键词：acute ischemic stroke blood-brain barrier glial growth factor 2 CAVEOLIN-1 Mfsd2a Pdlim5 
Decreasing productivity of pine forests on the southern edge of the Mongolian Plateau as indicated by tree rings
《Journal of Forestry Research》2024年第5期171-181,共11页Zhuolan Shen Shijie Wang Feng Chen Heli Zhang Xiaoen Zhao Youping Chen Mao Hu 
supported by the National Natural Science Foundation of China(32061123008).
Vegetation productivity on the southern edge of the Inner Mongolian Plateau,which plays a vital role in the ecological environment and in the arable and pasto-ral production in this region,can be characterized by the ...
关键词：DROUGHT Semi-arid area Peru current Yinshan Mountains 
Increasing concentrations of dietary threonine,tryptophan,and glycine improve growth performance and intestinal health with decreasing stress responses in broiler chickens raised under multiple stress conditions
《Animal Nutrition》2024年第3期145-153,共9页Hyun Woo Kim Jong Hyuk Kim Gi Ppeum Han Dong Yong Kil 
supported by Basic Science Research Program through the National Research Foundation of Korea (NRF)funded by the Ministry of Education (2021 R111A1 A010501414);supported by the Chung-Ang University Graduate Research Scholarship in 2023.
The current study aimed to compare the effects of increasing concentrations of dietary threonine(Thr),tryptophan(Trp),and glycine(Gly)on growth performance,stress biomarkers,and intestinal function in broiler chickens...
关键词：Broiler chicken GLYCINE Multiple stress THREONINE TRYPTOPHAN 
Disappearing sperms and changing climate:correlating decreasing semen quality and population dynamics within the Sustainable Development Goals framework
《Gynecology and Obstetrics Clinical Medicine》2024年第3期177-186,共10页Pallav Sengupta Sulagna Dutta 
Background Recent studies have reported a significant decline in human semen quality worldwide,raising concerns about climate change and its extensive effects on human health and biodiversity.Methods This article inve...
关键词：SUSTAINABLE dynamics DECREASING 
Retraction: Liquiritigenin Inhibits Colorectal Cancer Proliferation, Invasion, and Epithelial-to-Mesenchymal Transition by Decreasing Expression of Runt-Related Transcription Factor 2
《Oncology Research》2024年第8期1373-1373,共1页Oncology Research Editorial Office 
Following the publication,concerns have been raised about a number of figures in this article.The western blots in this article were presented with atypical,unusually shaped and possibly anomalous protein bands in man...
关键词：Cancer raised Transition 
A Qualitative Look at Decreasing Barriers to Receiving Uninterrupted Care for People Living with HIV in Rural Southern Georgia
《Open Journal of Nursing》2024年第8期447-458,共12页Joshua M. Kies 
Early linkage to antiretroviral therapy (ART) after HIV diagnosis extends life. Low socioeconomic populations with HIV face regional concerns that inhibit early treatment. Barriers include religious-based stigma, lack...
关键词：Antiretroviral Treatment (ART) Barriers COMPLIANCE HIV RURAL 
Deficiency of betaine-homocysteine methyltransferase activates glucose-6-phosphate dehydrogenase(G6PD)by decreasing arginine methylation of G6PD in hepatocellular carcinogenesis
《Science China(Life Sciences)》2024年第8期1648-1665,共18页Jie Gao Xiaoyi Shi Yaohui Sun Xudong Liu Feng Zhang Chengcheng Shi Xiao Yu Zhiping Yan Long Liu Shizhe Yu Jiacheng Zhang Xiaodan Zhang Shuijun Zhang Wenzhi Guo 
supported by the National Natural Science Foundation of China(82103282);Higher Education Disciplinary Innovation Program(D20036);Henan Province Medical Science and Technology Research Plan(SBGJ202103061,LHGJ20190135);“Science and Technology to create Central Plains”Young Talent Lifting Project(2023HYTP041);Henan Charity General Federation of Hepatobiliary Care Fund(GDXZ2023002).
Betaine-homocysteine methyltransferase(BHMT)regulates protein methylation and is correlated with tumorigenesis;however,the effects and regulation of BHMT in hepatocarcinogenesis remain largely unexplored.Here,we deter...
关键词：HCC BHMT arginine methylation G6PD PPP metabolism 
Enhancing thermoelectric performance of p-type SnTe through manipulating energy band structures and decreasing electronic thermal conductivity
《Rare Metals》2024年第7期3232-3241,共10页Xin Qian Hao-Ran Guo Jia-Xin Lyu Bang-Fu Ding Xing-Yuan San Xiao Zhang Jiang-Long Wang Shu-Fang Wang 
financially supported by the National Natural Science Foundation of China (Nos.52102234 and 51972094);the High-level Talents Research Initiation Project of Hebei University (No.521000981421);Hebei Province Introduced Overseas Student Funding Project (No.C20210313)。
SnTe has received considerable attention as an environmentally friendly alternative to the representative thermoelectric material of PbTe.However,excessive hole carrier concentration in SnTe results in an extremely lo...
关键词：Thermoelectric materials SnTe Energy band structure Electronic thermal conductivity ZT value 
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