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Emerging potential of progranulin-dependent SorCS2 signaling in healthy and diseased nervous systems
《Neural Regeneration Research》2025年第9期2591-2593,共3页Alena Salasova Anders Nykjær 
supported by Danish National Research Foundation(#DNRF133)(to AN)。
The formation of the mammalian nervous system and its maturation into sensory,motor,cognitive,and behavioral circuits is a complex process that begins during early embryogenesis and lasts until young adulthood.Impaire...
关键词：progr jointly CS2 
ADP‑dependent glucokinase:the ancient,archaeal key to prostate cancer
《Military Medical Research》2025年第3期467-468,共2页Marcin M.Kamiński 
The December 2023 issue of the Military Medical Research brings out an astounding discover y by Xu et al.[1]demonstrating a key role of the mysterious enzyme ADPdependent glucokinase(ADPGK)in the cellular metabolism o...
关键词：ADP-dependent glucokinase(ADPGK) Prostate cancer Prognostic marker ADENOCARCINOMA AMPactivated protein kinase(AMPK) Aldolase C(ALDOC) 
Quantile Regression under Truncated,Censored and Dependent Assumptions
《Acta Mathematicae Applicatae Sinica》2025年第2期479-497,共19页Chang-sheng LIU Yun-jiao LU Si-li NIU 
supported by the National Natural Science Foundation of China(12071348);the Key Scientific Research Foundation of Henan Educational Committee(24A110001);Key Laboratory of Intelligent Computing and Applications(Ministry of Education),Tongji University,China.
In this paper,we focus on the problem of nonparametric quantile regression with left-truncated and right-censored data.Based on Nadaraya-Watson(NW)Kernel smoother and the technique of local linear(LL)smoother,we const...
关键词：asymptotic normality asymptotic representation nonparametric quantile regression truncated and censored -MIXING 
Insight into the crystal facet-dependent Cr(VI)reduction:A comparative study of pyrite{100}and{111}facets
《Journal of Environmental Sciences》2025年第4期78-90,共13页Binlin Tang Jinye Liang Zhilin Wen Yueqiang Zhou Zhiqiang Yan Yihao Zhou Peng He Chunyao Gu Min Gan Jianyu Zhu 
supported by the National Natural Science Foundation of China(No.42277256);the Natural Science Foundation of Hunan Province(No.2022JJ30710);Hunan Province Environmental Protection Research Program(No.HBKT-2021014);Guangdong Province Dabaoshan Mining Co.Ltd Technology Program(Semi-industrial test of 200T/time low-grade copper ore bio-heap leaching).
The migration and transformation of hexavalent chromium(Cr(VI))in the environment are regulated by pyrite(FeS2).However,variations in pyrite crystal facets influence the adsorption behavior and electron transfer betwe...
关键词：PYRITE Cr(VI)reduction Facet-dependent Fe/S arrangement DFT calculation 
Construction of a Prognostic Model for Lysosome-dependent Cell Death in Gastric Cancer Based on Single-cell RNA-seq and Bulk RNA-seq Data
《Biomedical and Environmental Sciences》2025年第4期416-432,共17页Peng Ni Kaixin Guo Tianyi Liang Xinshuang Fan Yanqiao Hua Yangye Gao Shuaiyin Chen Guangcai Duan Rongguang Zhang 
supported by Hainan Provincial Natural Science Foundation of China(No.820CXTD438);National Natural Science Foundation of China(No.82160634, No.81773495)。
Objective To identify prognostic genes associated with lysosome-dependent cell death(LDCD)in patients with gastric cancer(GC).Methods Differentially expressed genes(DEGs)were identified using The Cancer Genome Atlas-S...
关键词：Gastric cancer Lysosomal dependent cell death Single-cell analysis Risk model Immune infiltration 
Emd-D inhibited ovarian cancer progression via PFKFB4-dependent glycolysis and apoptosis
《Chinese Journal of Natural Medicines》2025年第4期431-442,共12页Xin Zhao Chao Chen Xuefei Feng Haoqi Lei Lingling Qi Hongxia Zhang Haiying Xu Jufeng Wan Yan Zhang Baofeng Yang 
funded by the Natural Science Foundation of Heilongjiang Province(No.LH2023H012);Postdoctoral Research Initiation Fund(No.LBH-Q20152);CAMS Innovation Fund for Medical Sciences(CIFMS,2019-I2M-5-078)。
Ovarian cancer poses a significant threat to women's health,necessitating effective therapeutic strategies.Emd-D,an emodin derivative,demonstrates enhanced pharmaceutical properties and bioavailability.In this study,C...
关键词：Ovarian cancer Emd-D GLYCOLYSIS APOPTOSIS PFKFB4 
Unraveling the potential-dependent degradation mechanism in Fe–N–C catalysts for oxygen reduction reaction
《Science China Chemistry》2025年第4期1541-1549,共9页Yuyi Chu Yuqing Cheng Pengbo Wang Jingsen Bai Xin Guan Shuo Wang Chang Lan Hongxiang Wu Zhaoping Shi Siyuan Zhu Wei Liu Changpeng Liu Meiling Xiao Wei Xing 
supported by the National Key R&D Program of China(2022YFB4004100);the National Natural Science Foundation of China(22272161,and 22179126);Jilin Province Science and Technology Development Program(20210502002ZP,YDZJ202202-CXJD011,and 20240101019JC).
Fe–N–C is hailed as the most promising candidate for replacing costly platinum-based catalysts for proton-exchange membrane fuel cells(PEMFCs)owing to their impressive catalytic activity and low cost.However;the dur...
关键词：oxygen reduction reaction Fe-N-C catalysts stability mechanism carbon oxidation reactive oxygen species 
Porphyromonas gingivalis potentiates stem-like properties of oral squamous cell carcinoma by modulating SCD1-dependent lipid synthesis via NOD1/KLF5 axis
《International Journal of Oral Science》2025年第1期133-146,共14页Wenli Zang Fengxue Geng Junchao Liu Zengxu Wang Shuwei Zhang Yuchao Li Ze Lu Yaping Pan 
supported by the National Natural Science Foundation of China(grant#82370975 and 82170969)。
Cancer stem cells(CSCs)are widely acknowledged as primary mediators to the initiation and progression of tumors.The association between microbial infection and cancer stemness has garnered considerable scholarly inter...
关键词：NOD1 gingivalis SCD1 
The boundedness in a chemotaxis-haptotaxis system with ECM-dependent sensitivity
《Applied Mathematics(A Journal of Chinese Universities)》2025年第1期20-32,共13页LIU Jiao LI Zhong-ping 
Supported by the National Natural Science Foundation of China(11301419);the Research and innovation Team of China West Normal University(CXTD2020-5)。
This paper deals with a chemotaxis-haptotaxis system with ECM-dependent sensitivity under the Neumann boundary conditions in a smooth bounded domain.It is shown that the system possesses a globally bounded solution un...
关键词：global boundedness chemotaxis-haptotaxis ECM-dependent sensitivity 
Law of large numbers for m-dependent random vectors under sublinear expectations
《Probability, Uncertainty and Quantitative Risk》2025年第1期1-12,共12页Mingcong Wu Guanghui Cheng 
funded by the National Nature Science Foundation of China(Grant No.12001128);the GuangDong Basic and Applied Basic Research Foundation(Grant No.2022A1515011899).
Sublinear expectation relaxes the linear property of classical expectation to subadditivity and positive homogeneity,which can be expressed as E(·)=sup_(θ∈θ) E_(θ)(·)for a certain set of linear expectations{E_(...
关键词：Law of large numbers m-dependence Sublinear expectations Rate of convergence Random vectors 
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