supported by grants from the National Basic Research Program of China (No. 2013CB967102);the Strategic Priority Research Program of the Chinese Academy of Sciences (No. XDA01030506);the International S&T Cooperation Program of China (No. 2013DFG30680)
Human induced pluripotent stem cells (hiPSCs) can self-renew indefinitely and have the potential to differentiate into all cell types in the human body, thus hold great promise in regen- erative medicine, drug scree...
supported by grants from the National Key Basic Research Programs of China (Nos. 2012CB966600 and 2012CB967900);the National Natural Science Foundation Project (No. 31371506);the 12th Five-Year National Key Technologies R&D Program (No. 2012BAI12B00)
In all the connexin-associated human diseases, deafness is one of the most important diseases with high frequency. The mu- tations of GJB2 (gap junction protein β2, also called connexin 26, Cx26) gene link with non...
supported by the National Basic Research Program of China(Program 973)(Nos.2009CB941002 and 2011CB944202);the Distinguished Young Scholar Foundation of Heilongjiang Province(No.JC200905)
Embryonic germ (EG) cells are cultured pluripotent stem cells derived from the primordial germ cells (PGCs) that migrate from the dorsal mesentery of the hindgut to the developing genital ridge. In this study, the...
supported by the grants from the China National Basic Research Program(No.2012CB966501) to X.Z;the National High Technology R&D Program of China (No.2011AA020108) to Q.Z.;the "Strategic Priority Research Program" of the Chinese Academy of Sciences(No. XDA01030101)
The laboratory rat was one of the earliest mammalian species for scientific research and used as animal disease models in physiology, toxicology, behavior, immunology, and tumor-biology for over 150 years (Jacob, 199...
This work was partially supported by grants from the National Key Basic Research and Development Program of China(Nos.2007CB948003,2009CB940900,2009CB941000, 2009CB941100,2006CB943901,2007CB947902 and 2011 CB965101);the National Natural Science Foundation of China (Nos.30621091 and 31025016);the Chinese Academy of Sciences Knowledge Creation Program(No.KSCX1-YW-R- 54,KSCX1-YW-R-46);the Shanghai Science & Technology Developmental Foundation(No.08DJ1400500);the National High Technology Research and Development Program(863 program) of China(No.2010AA100504);the Shanghai Institutes for Biological Sciences(No.2007KIP401)
Human embryonic stem cells (hESCs) can self-renew indefinitely and differentiate into all cell types in the human body. Therefore, they are valuable in regenerative medicine, human developmental biology and drug dis...
supported in part by the grants from the Chinese National Basic Research Program (No 2007CB948001);the National High Technology R&D Program of China (No 2006AA02A101);Integrated Project funded by the Sixth Framework Programme (FP6) of the European Union (Contract:LSHG-CT-2005-019015)
Knockout Brown Norway (BN) rat could be a useful disease model for human disorders,however,a failure to derive embryonic stem (ES) cells disturbs the further development of the model.In this study,we reported a ca...
supported by the National Institute of Health,USA (No.R21 RR025408)
Induced pluripotent stem (iPS) cells can be derived from human somatic cells by cellular reprograrnming. This technology provides a potential source of non-controversial therapeutic ceils for tissue repair, drug dis...
the Guangdong Province Health Department (No. B30202);Guangzhou City Science and Technology Administration (No. 2006Z1-E0021);partly supported by the Guangdong Province Science and Technology Administration (No. 2007A032100003);Guangdong Provincial Medical Research Fund (No. A2008287)
Poor quality embryos discarded from in vitro fertilization (IVF) laboratories are good sources for deriving human embryonic stem cell (hESC) lines. In this study, 166 poor quality embryos donated from IVF centers ...