DERIVATION

作品数:425被引量:542H指数:9
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相关领域:理学更多>>
相关作者:王德威李杰邱亚峰张朝凤马丽丽更多>>
相关机构:韶关学院哈佛大学复旦大学南京理工大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>
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Efficient Derivation of Human Induced Pluripotent Stem Cells with a c-Myc-Free Non-Integrating Episomal Vector
《Journal of Genetics and Genomics》2016年第3期161-164,共4页Juan Wang Qi Gu Jie Hao Donghui Bai Liu Wang Zhonghua Liu Qi Zhou 
supported by grants from the National Basic Research Program of China (No. 2013CB967102);the Strategic Priority Research Program of the Chinese Academy of Sciences (No. XDA01030506);the International S&T Cooperation Program of China (No. 2013DFG30680)
Human induced pluripotent stem cells (hiPSCs) can self-renew indefinitely and have the potential to differentiate into all cell types in the human body, thus hold great promise in regen- erative medicine, drug scree...
关键词:PSCs CELL In SSEA SOX 
Derivation of Non-Integration Induced Pluripotent Stem Cells from Fibroblast of Severe Deafness Patients with GJB2 Mutation被引量:1
《Journal of Genetics and Genomics》2015年第8期455-458,共4页Xiaofeng Jin Rui Fu Wanwan Zhu Zhengxin Liu Tiantian Gu Guanyi Jiao Hua Yang Qi Zhou Zhiqiang Gao Xiao-Yang Zhao 
supported by grants from the National Key Basic Research Programs of China (Nos. 2012CB966600 and 2012CB967900);the National Natural Science Foundation Project (No. 31371506);the 12th Five-Year National Key Technologies R&D Program (No. 2012BAI12B00)
In all the connexin-associated human diseases, deafness is one of the most important diseases with high frequency. The mu- tations of GJB2 (gap junction protein β2, also called connexin 26, Cx26) gene link with non...
关键词:GJB In PSCs 
Derivation of Putative Porcine Embryonic Germ Cells and Analysis of Their Multi-Lineage Differentiation Potential被引量:4
《Journal of Genetics and Genomics》2013年第9期453-464,共12页Yimei Cong Jing Ma Ruizhen Sun Jianyu Wang Binghua Xue Jiaqiang Wang Bingteng Xie Juan Wang Kui Hu Zhonghua Liu 
supported by the National Basic Research Program of China(Program 973)(Nos.2009CB941002 and 2011CB944202);the Distinguished Young Scholar Foundation of Heilongjiang Province(No.JC200905)
Embryonic germ (EG) cells are cultured pluripotent stem cells derived from the primordial germ cells (PGCs) that migrate from the dorsal mesentery of the hindgut to the developing genital ridge. In this study, the...
关键词:Embryonic germ cells: Primordial germ ceils Multi-lineage differentiation SWINE 
Derivation of Germline Competent Rat Embryonic Stem Cells from DA Rats被引量:3
《Journal of Genetics and Genomics》2012年第11期603-606,共4页Tianda Li Xiao-Yang Zhao Fei Teng Xin Li Minggui Jiang Wei Li Xuepeng Wang Jialiang Wang Lei Liu Zhonghua Liu Liu Wang Qi Zhou 
supported by the grants from the China National Basic Research Program(No.2012CB966501) to X.Z;the National High Technology R&D Program of China (No.2011AA020108) to Q.Z.;the "Strategic Priority Research Program" of the Chinese Academy of Sciences(No. XDA01030101)
The laboratory rat was one of the earliest mammalian species for scientific research and used as animal disease models in physiology, toxicology, behavior, immunology, and tumor-biology for over 150 years (Jacob, 199...
Derivation and characterization of human embryonic stem cell lines from the Chinese population被引量:3
《Journal of Genetics and Genomics》2011年第1期13-20,共8页Zhao Wu Hui Li Lingjun Rao Lixiaz iHe Lei Bao Jing Liao Chun Cui Zhenyu Zuo Qiao Li Huimin Dai Lei Qian Qing Tian Lei Xiao Xiao junTan 
This work was partially supported by grants from the National Key Basic Research and Development Program of China(Nos.2007CB948003,2009CB940900,2009CB941000, 2009CB941100,2006CB943901,2007CB947902 and 2011 CB965101);the National Natural Science Foundation of China (Nos.30621091 and 31025016);the Chinese Academy of Sciences Knowledge Creation Program(No.KSCX1-YW-R- 54,KSCX1-YW-R-46);the Shanghai Science & Technology Developmental Foundation(No.08DJ1400500);the National High Technology Research and Development Program(863 program) of China(No.2010AA100504);the Shanghai Institutes for Biological Sciences(No.2007KIP401)
Human embryonic stem cells (hESCs) can self-renew indefinitely and differentiate into all cell types in the human body. Therefore, they are valuable in regenerative medicine, human developmental biology and drug dis...
关键词:Human embryonic stem cells PLURIPOTENCY Chinese population 
Derivation of embryonic stem cells from Brown Norway rats blastocysts被引量:5
《Journal of Genetics and Genomics》2010年第7期467-473,共7页Xiaoyang Zhao Zhuo Lv Lei Liu Liu Wang Man Tong Qi Zhou 
supported in part by the grants from the Chinese National Basic Research Program (No 2007CB948001);the National High Technology R&D Program of China (No 2006AA02A101);Integrated Project funded by the Sixth Framework Programme (FP6) of the European Union (Contract:LSHG-CT-2005-019015)
Knockout Brown Norway (BN) rat could be a useful disease model for human disorders,however,a failure to derive embryonic stem (ES) cells disturbs the further development of the model.In this study,we reported a ca...
关键词:Brown Norway (BN) rat embryonic stem cells PLURIPOTENCY chimera rat 
SNL fibroblast feeder layers support derivation and maintenance of human induced pluripotent stem cells被引量:5
《Journal of Genetics and Genomics》2010年第4期241-248,共8页Chuanying Pan Amy Hicks Xuan Guan Hong Chen Colin E. Bishop 
supported by the National Institute of Health,USA (No.R21 RR025408)
Induced pluripotent stem (iPS) cells can be derived from human somatic cells by cellular reprograrnming. This technology provides a potential source of non-controversial therapeutic ceils for tissue repair, drug dis...
关键词:induced pluripotent stem cells DERIVATION maintenance SNL feeder cells 
Derivation and characterization of human embryonic stem cell lines from poor quality embryos被引量:3
《Journal of Genetics and Genomics》2009年第4期229-239,共11页Weiqiang Liu, Yifei Yin, Xiaolin Long, Yumei Luo, Yonghua Jiang, Wenhong Zhang, Hongzi Du, Shaoying Li, Yuhong Zheng, Qing Li, Xinjie Chen, Baoping Liao, Guohong Xiao, Weihua Wang, Xiaofang Sun Guangzhou Key Laboratory of Reproductive and Genetics Institute of Gynecology and Obstetrics, The Third Affiliated Hospital of Guangzhou Medical College, Guangzhou 510150, China 
the Guangdong Province Health Department (No. B30202);Guangzhou City Science and Technology Administration (No. 2006Z1-E0021);partly supported by the Guangdong Province Science and Technology Administration (No. 2007A032100003);Guangdong Provincial Medical Research Fund (No. A2008287)
Poor quality embryos discarded from in vitro fertilization (IVF) laboratories are good sources for deriving human embryonic stem cell (hESC) lines. In this study, 166 poor quality embryos donated from IVF centers ...
关键词:embryonic stem ceils poor quality embryos inner cell mass mechanical isolation immunosurgery 
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