This work was supported in part by the grants from the National Natural Science Foundation of China(Nos.31470435 and 31570843).
A large number of proteins involved in RNA metabolism possess a double-stranded RNA-binding domain(dsRBD),whose sequence variations and functional versatilities are still being recognized.All dsRBDs have a similar str...
The NCCR RNA and disease funded by the Swiss National Science Foundation (SNF; 51NF40_141735) for access to the Biomolecular NMR spectrometry platform at ETH ZUrich. This work was supported by an IIF Marie Curie fellowship to TI (no. 329029) and a European Research Council (ERC) advanced grant "Frontiers of RNAi-Ⅱ" to OV (no. 323071).
In eukaryotes, the RNase-Ⅲ Dicer often produces length/sequence microRNA (miRNA) variants, called "isomiRs", owing to intrinsic structural/sequence determinants of the miRNA precursors (pre-miRNAs). In this stu...
MicroRNAs(miRNAs)constitute a class of small non-coding RNAs that participate in various biological processes by repressing protein translation or destabilizing target mRNAs.miRNA biogenesis begins with the transcri...
This research was supported in part by the Special Fund for Agro-scientific Research in the Public In- terest (201203038), the Natural Science Foundation of Chongqing (CSTC, 2013jjB0176), the earmarked fund for Modern Agro-industry (Citrus) Technology Research System, and the Foundation Project of Southwest Univer- sity (SWU114049). We thank Kun Zhang for his technical assistance in this study.
RNA interference (RNAi)-based technology has emerged as a potential tool for controlling insect pests, however, previous studies found that the efficiency of RNAi in Bactrocera dorsalis was variable. In nature, inse...