DOXYCYCLINE

作品数：68被引量：168H指数：7
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Establishment and characterization of a new cell culture system for hepatitis B virus replication and infection被引量：1
《Virologica Sinica》2022年第4期558-568,共11页Yingying Song Shuyu Shou Huimin Guo Zixiang Gao Nannan Liu Yang Yang Feifei Wang Qiang Deng Jing Liu Youhua Xie 
the National Natural Science Foundation of China(81971921,81971931);the National base cultivation project(20DZ2210404);the Major science and technology project for the prevention and treatment of major infectious diseases(2018ZX10301208)。
Hepatitis B virus(HBV)is a primary cause of chronic liver diseases in humans.HBV infection exhibits strict host and tissue tropism.HBV core promoter(Cp)drives transcription of pregenomic RNA(pg RNA)and plays a key rol...
关键词：Hepatitis B virus(HBV) Sodium-taurocholate cotransporting polypeptide(NTCP) BEL7404 Hepatocyte nuclear factor 4α(HNF4α) Tetracycline(Tet)-On Doxycycline(DOX) 
An improved Tet-on system in micro RNA overexpression and CRISPR/Cas9-mediated gene editing被引量：4
《Journal of Animal Science and Biotechnology》2019年第4期1089-1100,共12页Kang Kang Lian Huang Qing Li Xiaoyun Liao Quanjin Dang Yi Yang Jun Luo Yan Zeng Li Li Deming Gou 
partly supported by National Natural Science Foundation of China(31571199,81570046,91739109,81870045,and 81700054);the Shenzhen Municipal Basic Research Program JCYJ20150729104027220 and JCYJ20170818144127727;Interdisciplinary Innovation Team Project of Shenzhen University
Background: Tetracycline(Tet)-regulated expression system has become a widely applied tool to control gene activity. This study aimed to improve the Tet-on system with superior regulatory characteristics.Results: By c...
关键词：CRISPR/Cas9 DOXYCYCLINE microRNA NFAT5 TETRACYCLINE 
Generation and Characterization of a Transgenic Zebrafish Expressing the Reverse Tetracycline Transactivator
《Journal of Genetics and Genomics》2013年第10期523-531,共9页Qilin Gu Xiaojie Yang Xiaozhen He Qing Li Zongbin Cui 
supported by the grants from the National Basic Research Program of China(No.2012CB944500);the National Natural Science Foundation of China(No.31171390 to Z.Cui)
Conditional expression of a target gene during zebrafish development is a powerful approach to elucidate gene functions. The tetracycline-controlled systems have been successfully used in the modulation of gene expres...
关键词：Zebrafish TRANSGENE Tet-on system Reverse Tet transactivator DOXYCYCLINE 
A SINGLE TETRACYCLINE-REGULATED VECTOR DEVISED FOR CONTROLLED INSULIN GENE EXPRESSION
《Chinese Medical Sciences Journal》2004年第4期266-269,共4页Xue-yangZhang Ben-liSu HongLi RanBai Zhao-huiXu Chang-chenLi 
Supported by a grant from the Educational Department of Liaoning Province (99022067).
Objective To construct a single plasmid vector mediating doxycycline-inducible recombined human insulin gene expr-ession in myotube cell line. Methods An expression cassette of rtTAnls driven by promoter of human cyto...
关键词：DOXYCYCLINE TETRACYCLINE insulin gene therapy diabetes mellitus 
Killing effect of TNF-related apoptosis inducing ligand regulated by tetracycline on gastric cancer cell line NCI-N87被引量：11
《World Journal of Gastroenterology》2001年第4期559-562,共4页Xiao-Chao Wei Xin-Juan Wang Kai-Chen Lei Zhang Yu Liang Xin-Li Lin Department of Biochemistry and Molecular Biology,Peking University Health Science Center,Beijing 100083,ChinaProtein Studies,Oklahoma Medical Research Foundation,Oklahoma City,OK 73104,USA 
the National Natural Science Foundation of China,No.39870850
AIM: To clone the cDNA fragment of human TRAIL (TNF-related apoptosis inducing ligand) into a tetracycline-regulated gene expression system, the RevTet-On system, transduce expression vectors into a gastric carcinoma ...
关键词：Stomach Neoplasms 3T3 Cells Animals Anti-Bacterial Agents APOPTOSIS Apoptosis Regulatory Proteins DOXYCYCLINE Gene Expression Regulation  Neoplastic Genetic Vectors Humans Jurkat Cells Membrane Glycoproteins Mice Research Support  Non-U.S. Gov't RETROVIRIDAE Transfection Tumor Necrosis Factor-alpha 
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