EFAVIRENZ

作品数：36被引量：52H指数：4
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相关作者：胡康洪魏艳红李太生郭伏平张庆刚更多>>
相关机构：湖北工业大学北京协和医院山东师范大学浙江工业大学更多>>
相关期刊：《International Journal of Modern Nonlinear Theory and Application》《Journal of Applied Mathematics and Physics》《Emerging Contaminants》《现代生物医学进展》更多>>
相关基金：国家自然科学基金泰国研究基金更多>>
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The differential effects of integrase strand transfer inhibitors and efavirenz on neuropsychiatric conditions and brain imaging in HIV-positive men who have sex with men被引量：2
《Biosafety and Health》2024年第4期216-224,共9页Yihui He Yang Zhang Jiaxin Zhen Guangqiang Sun Zhen Li Bo Yang Bin Yang Keyi Chang Xue Chen Yulin Zhang Caiping Guo Wen Wang Ping Wu Tong Zhang Lei Wang 
supported by the National Natural Science Foundation of China(82072271,82241072,82072294);the National Key Research and Development Program of China(2021YFC2501402,2021YFC0122601);the Beijing Natural Science Foundation(7222095,7222091);the Peak Talent Program of Beijing Hospital Authority(DFL20191701);the Capital’s Funds for Health Improvement and Research(2022-1-1151);the Research and Translational Application of Clinical Characteristic Diagnostic and Treatment Techniques in Capital City(Z221100007422055);the Beijing Research Center for Respiratory Infectious Diseases(BJRID2024-001);the Beijing Hospitals Authority Innovation Studio of Young Staff Funding Support(2021037);the High-level Public Health Technical Personnel Construction Project(2022-1-007);the High-level Public Health Specialized Talents Project of Beijing Municipal Health commission(2022-02-20);the Beijing Key Laboratory for HIV/AIDS Research(BZ0089).
Integrase strand transfer inhibitors(INSTIs)have emerged as the first‐line choice for treating human immunodeficiency virus(HIV)infection due to their superior efficacy and safety.However,the impact of INSTIs on the ...
关键词：Human immunodeficiency virus(HIV) Multimodal magnetic resonance imaging(MRI) Integrase strand transfer inhibitors(INSTIs) Efavirenz(EFV) 
Changes in blood lipid levels and influencing factors among treatment-naïve adult male HlV/AlDS patients following BlC/FTC/TAF vs.3TC+EFV+TDF
《Chinese Medical Journal》2024年第12期1447-1452,共6页Xi Wang An Liu Zaicun Li Hongwei Zhang Ruojun Esther Wu Ying Shao Jianwei Li Jiangzhu Ye Wei Liu Lijun Sun 
supported by the Gilead Sciences and the Capital Health Research and Development of Special Fund(No.2022-1G-3015)
Background:Antiretroviral therapy(ART)was often associated with dyslipidemia among human immunodeficiency virus(HIV)/acquired immunodeficiency syndrome(AIDS)patients.This study aimed to assess treatment-naïve adult ma...
关键词：Antiretroviral therapy Blood lipids Bictegravir/emtricitabine/tenofovir alafenamide Lamivudine efavirenz and tenofovir disoproxil fumarate BIC/FTC/TAF 3TC+EFV+TDF HIV AIDS 
Outcomes of bictegravir/emtricitabine/tenofovir alafenamide versus efavirenz-based regimens in central China:a real-world assessment
《Chinese Medical Journal》2023年第22期2738-2740,共3页Yongquan Peng Xujian Cao Yating Wang Weiwei Yu Ziwei Zeng Min Wang 
supported by the Research project of Hunan Provincial Department of Science and Technology(No.2020SK21361)
To the Editor:Human immunodeficiency virus(HIV)epidemic poses a significant challenge to global public health.As of 2022,approximately 39.0 million people worldwide were living with HIV.[1]With the ongoing evolution o...
关键词：REGIMEN drugs approval 
Developmental abnormalities and growth patterns in juvenile Oreochromis mossambicus chronically exposed to efavirenz
《Emerging Contaminants》2022年第1期83-89,共7页Saisha Kowlaser Irene Barnhoorn Ina Wagenaar 
the MSc dissertation of Ms S.Kowlaser,the research was supported in part by the National Research Foundation of South Africa(Unique Grant Number 86056;119318 and 98719).
Efavirenz is an antiretroviral drug(ARV)used for the treatment of Human Immunodeficiency Virus(HIV/AIDS)infections.The effects efavirenz may have on mammals is known,however,little is known about the effects on non-ta...
关键词：EXPOSED JUVENILE alterations 
Switching from efavirenz to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide reduces central nervous system symptoms in people living with HIV被引量：5
《Chinese Medical Journal》2021年第23期2850-2856,共7页Huan Xia Xiao-Jie Huang Yue Hu Li-Ying Gao Yue Wu Hao Wu Zhong-Fang Yan Ping Ma 
the 13th Five-year National Major Project for HIV/AIDS and Hepatitis B Control and Prevention and the Chinese Ministry of Science and Technology(No.2017ZX10202102005004).
Background:Central nervous system(CNS)symptoms after efavirenz(EFV)treatment in people living with human immunodeficiency virus(HIV)could persist and impact their quality of life.We assessed the impact of EFV-based re...
关键词：HIV EFAVIRENZ Elvitegravir Tenofovir alafenamide Central nervous system 
Effect of ABCB1 3435C>T transporter gene polymorphism on plasma efavirenz concentration in HIV-1 infected Thai adults
《Asian Pacific Journal of Tropical Medicine》2020年第6期266-271,共6页Sahapat Barusrux Napatrupron Koomdee Rattanaporn Sukprasong Weerawat Manosuthi Monpat Chamnanphon Apichaya Puangpetch Chonlaphat Sukasem Veeranoot Nissapatorn Maria de Lourdes Pereira 
supported by Mahidol University,Thailand Research Fund,Thailand Office of the Higher Education Commission under New Researchers Grant(MRG 5480136);the project CICECOAveiro Institute of Materials,national funds through the FCT/MCTES(FCT Ref.UID/CTM/50011/2019);Rachadapisek Sompote Fund for Postdoctoral Fellowship,Chulalongkorn University
Objective:To investigate the influence of ABCB1 polymorphisms on the plasma level of efavirenz in Thai adult cases infected with HIV-1.Methods:A single nucleotide polymorphism of ABCB13435 C>T(rs1045642)in the gene en...
关键词：Transporter gene ABCB13435C>T EFAVIRENZ HIV-1 THAI 
中国人类免疫缺陷病毒感染者依非韦伦浓度前瞻性评估研究被引量：5
《中华内科杂志》2018年第11期846-847,共2页郭伏平 李太生 
2018年5月HIV Medicine在线发表了北京协和医院感染内科李太生教授牵头的一项多中心研究——＂中国人类免疫缺陷病毒感染者依非韦伦浓度前瞻性评估研究＂[Guo F,Cheng X,Hsieh E,et al. Prospective plasma efavirenz concentration ass...
关键词：中国医学科学院 人类免疫缺陷 前瞻性评估 病毒感染者 依非韦伦 血药浓度 EFAVIRENZ HIV感染者 
Fulminant Hepatitis Following Ritonavir-Nevirapine-Efavirenz Regimen in a Female HIV Patient in Pointe-Noire in 2016
《Open Journal of Gastroenterology》2018年第5期167-171,共5页Firmin Bossali G. Ndziessi G. Deby C. R. Ahoui Apendi J. F. Mimiesse B. I. Atipo-Ibara J. R. Ibara 
Current antiretroviral therapy has reduced morbidity and mortality of HIV patients. However, their induced hepatotoxicity constitutes a risk. In this issue, we report a clinical case of fulminant hepatitis, observed i...
关键词：FULMINANT Hepatitis HEPATOTOXICITY ANTIRETROVIRAL Therapy Pointe-Noire 
Formulation and Solid-State Characterisation of a Novel Benzanilide Co-crystal of the Anti-HIV Drug Efavirenz
《Journal of Pharmacy and Pharmacology》2018年第3期274-285,共12页Maryam Amra Jordaan Michael Shapi 
HIV/AIDS has had a crippling socio-economic effect on developing countries in Africa. EFV （Efavirenz） is generally used to treat this pathology. However, its clinical efficacy is reduced by its limited water solubil...
关键词：CCS EFV BZA X-ray Powder Diffraction （XRD） FTIR. 
Enhanced dissolution of poorly soluble antiviral drugs from nanoparticles of cellulose acetate based solid dispersion matrices
《Asian Journal of Pharmaceutical Sciences》2017年第6期532-541,共10页Sonal Mazumdera Ashish Kumar Dewangan Naresh Pavurala 
supported by Research Initiation Grant,BITS Pilani,Pilani campus,India
Polysaccharide-based polymers were used to produce nanoparticles of poorly soluble antiviral drugs using a rapid precipitation process. The structure-property relationships of four novel cellulose acetate-based polyme...
关键词：Solid DISPERSIONS Ritonavir EFAVIRENZ NANOPARTICLES Precipitation SOLUBILITY 
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