supported by the funds of Guangdong Basic and Applied Basic Research Foundation(2019B030302012);the National Key R&D Program of China(2021YFC2501001,2022YFC3401002);Shenzhen Medical Research Funds(C2303002);the National Natural Science Foundation of China(82341024,82172930,82203286);the Major Program of Shenzhen Bay Laboratory(S201101004);China Postdoctoral Science Foundation(BX20220214).
Objectives:Resistance to apoptosis in esophageal squamous cell carcinoma(ESCC)constitutes a significant impediment to treatment efficacy.Exploring alternative cell death pathways and their regulatory factors beyond ap...
Objective To investigate the expression of cyclin-dependent kinase 8(CDK8)in esophageal squamous cell carcinoma(ESCC)and its effect on ESCC cells,and to explore its potential molecular mechanism.Methods The expression...
funded by National Natural Science Foundation of China(grant numbers:81872335,82303891 and 82303119);The Central Plains Science and Technology Innovation Leading Talents(No.224200510015,China);Key scientific research project plan of colleges and universities in Henan Province(grant number:24A310025,China);Science and Technology Project of Henan Province(No.242102310414,China).
Esophageal squamous cell carcinoma(ESCC),a malignancy of the digestive system,is highly prevalent and the primary cause of cancer-related deaths worldwide due to the lack of early diagnostic biomarkers and effective t...