FLUORESCENCE

作品数:1389被引量:1995H指数:14
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相关领域:理学医药卫生更多>>
相关作者:郑安呐胡福增潘远凤黄建滨阎云更多>>
相关机构:中国科学院东南大学天津大学复旦大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>
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  • 期刊=Journal of Innovative Optical Health Sciencesx
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A generalized deep neural network approach for improving resolution of fluorescence microscopy images
《Journal of Innovative Optical Health Sciences》2024年第6期53-65,共13页Zichen Jin Qing He Yang Liu Kaige Wang 
Subjects funded by the National Natural Science Foundation of China(Nos.62275216 and 61775181);the Natural Science Basic Research Programme of Shaanxi Province-Major Basic Research Special Project(Nos.S2018-ZC-TD-0061 and TZ0393);the Special Project for the Development of National Key Scientific Instruments and Equipment No.(51927804).
Deep learning is capable of greatly promoting the progress of super-resolution imaging technology in terms of imaging and reconstruction speed,imaging resolution,and imagingflux.This paper proposes a deep neural netwo...
关键词:Deep learning super-resolution imaging generalized model framework generation adversarial networks image reconstruction. 
In vivo fluorescence flow cytometry reveals that the nanoparticle tumor vaccine OVA@HA-PEI effectively clears circulating tumor cells
《Journal of Innovative Optical Health Sciences》2024年第6期107-123,共17页Wei Jin Yuting Fu Sisi Ge Han Sun Kai Pang Xunbin Wei 
supported by the National Key Research and Development Program of China,Grant Number:2021YFF0502900,2019YFC1604604;National Natural Science Foundation of China,Grant Number:62075013,62027824.
Tumor vaccine therapy offers significant advantages over conventional treatments,including reduced toxic side effects.However,it currently functions primarily as an adjuvant treatment modality in clinical oncology due...
关键词:Tumor vaccines circulating tumor cells in vivo fluorescence flow cytometry. 
NIR-II fluorescence imaging in liver tumor surgery: A narrative review被引量:1
《Journal of Innovative Optical Health Sciences》2024年第1期29-44,共16页Zihao Liu Lifeng Yan Qingsong Hu Dalong Yin 
supported by the National Key R&D Program of China(No.2020YFA0710700);the National Natural Science Foundation of China(Nos.51873201 and 82172071);Key Research and Development Program of Anhui Province(No.202104b11020025);the Fundamental Research Funds for the Central Universities(No.YD2060002015);the CAS Youth Interdisciplinary Team(No.JCTD-2021-08).
In liver tumor surgery,the recognition of tumor margin and radical resection of microcancer focis have always been the crucial points to reduce postoperative recurrence of tumor.However,naked-eye inspection and palpat...
关键词:Fluorescence guided-surgery liver cancer near infrared-II optical imaging 
Development of water-soluble AIE-based wash-free Aβprobes superior to commercial ThT被引量:1
《Journal of Innovative Optical Health Sciences》2023年第6期3-12,共10页Ting-Ting Hou Ying-Hao Tang Zhen-Yu Zhang Ze-Jun Li Ya-Long Wang 
supported by the National Key R&D Program of China(2021ZD0201004);the National Natural Science Foundation of China(22165008,22077037,21474034,51673077 and 51603078);Hainan Provincial Natural Science Foundation of China(521RC506);the Open Project Program of Wuhan National Laboratory for Optoelectronics(No.2020WNLOKF018)。
Alzheimer's disease(AD)is a typical neurodegenerative disease.β-amyloid(AβÞplaque is the most prominent pathological biomarker associated with the progression of AD.Conventional Aβprobes,including commercial probe ...
关键词:Β-AMYLOID aggregation-induced emission fluorescence imaging 
Comparison of the emission wavelengths by a single fluorescent dye on in vivo 3-photon imaging of mouse brains被引量:1
《Journal of Innovative Optical Health Sciences》2023年第6期23-30,共8页Ke Wang Wanjian Zhang Xiangquan Deng Shen Tong Hui Cheng Mengyuan Qin Lei Zheng Kun Zhao Ruizhan Zhai Zhongqing Jia Ping Qiu 
work is funded by the National Natural Sci-ence Foundation of China(Grant/Award Numbers 62075135 and 61975126);Shenzhen Science and Technology Planning Project(ZDSYS2021-0623092006020);Key R&D Program of Shandong Province(Grant Number 2021CXGC010202);the Science and Technology Innovation Commission of Shenzhen(Grant/Award Numbers JCYJ201908-08174819083 and JCYJ20190808175201640)and Natural Science Foundation of Shandong Province(Grant Number ZR2022MA046);Major Innovation Projects for Integrating Science,Education&Industry of Qilu University of Technology(Shan-dong Academy of Sciences,Grant Number 2022JBZ01-04).
Multiphoton microscopy(MPM)is a powerful imaging technology for brain research.The imaging depth in MPM is partly determined by emission wavelength of fluorescent labels.It has been demonstrated that a longer emission...
关键词:3-Photon microscopy emission fluorescence FM4-64 Monte Carlo. 
Compact and robust dual-color linearly polarized illumination source for three-photon fluorescence imaging
《Journal of Innovative Optical Health Sciences》2023年第5期69-76,共8页Jiazheng Song Yanyan Zhang Yuanshan Liu 
supported by the Fundamental Re-search Funds for the Central Universities(HYGJXM202309).
The miniaturized femtosecond laser in near infrared-Ⅱregion is the core equipment of threephoton microscopy.In this paper,we design a compact and robust illumination source that emits dual-color linearly polarized li...
关键词:Three-photon fluorescence imaging illumination source dual-wavelength femtosecond pulse cascaded Raman effect graded-index multimodefiber. 
Quantitative tracing of bioprobes by simultaneously monitoring radiative and nonradiative relaxations
《Journal of Innovative Optical Health Sciences》2023年第4期40-47,共8页Hongjiang Chen Xiaoyu Tang Guangshuai Nie Zhen Wang Jia Hu Jun Hu Huan Qin 
supported by the National Natural Science Foundation of China (62075066);Guangdong Basic and Applied Basic Research Foundation (2021A1515011285,2019A1515010800);Major Project under the Science and Technology Development Scheme of Guangdong Province (210715106900918,[2020]53-129);Shantou Science and Technology Plan Medical and Health Category Project (211114216492935).
Bioprobe based on fluorescence is widely used in biological and medical research due to its high sensitivity and selectivity.Yet,its quantification in vivo is complicated and often compromised by the interaction betwe...
关键词:Bioprobe FLUORESCENCE PHOTOACOUSTIC 
Automated apoptosis identification in fluorescence imaging of nucleus based on histogram of oriented gradients of high-frequency wavelet coefficients
《Journal of Innovative Optical Health Sciences》2023年第2期28-38,共11页Shutong Liu Limei Su Han Sun Tongsheng Chen Min Hu Zhengfei Zhuang 
This work is supported by the Key Project of the National Natural Science Foundation of China(Grant Number 62135003);the Science and Technology Program of Guangzhou(Grant No.202201010704);Special Carrier Program of Qingyuan Hitech Industrial Development Zone.
The automatic and accurate identification of apoptosis facilitates large-scale cell analysis.Most identification approaches using nucleus fluorescence imaging are based on specific morphological parameters.However,the...
关键词:APOPTOSIS NUCLEUS fluorescence imaging HOG wavelet decomposition 
Fluorescence imaging analysis of the glioma microenvironment
《Journal of Innovative Optical Health Sciences》2023年第1期55-66,共12页Xuwen Peng Yuzhou Chen Yuke Wang Shuhong Qi 
supported by the National Natural Science Foundation of China (31700808);the Fundamental Research Funds for the Central Universities (2020kfyXJJS112).
Glioma is the most malignant brain cancer.The neurons,macrophages,T cells and other immune ellls constitute the glioma immunosuppressive microenvironment.The accurate spatial distri-bution of these cells in the glioma...
关键词:Glioma microenvironment spatial distribution heterogeneity multicolor immuno-fluorescence large Stokes-shifted fluorescent protein. 
A smartphone-based automated fluorescence analysis system for point-of-care testing of Hg(Ⅱ)
《Journal of Innovative Optical Health Sciences》2022年第5期28-40,共13页Yafei Chen Ke Zhang Yuan Liu Chunsun Zhang 
supported by the Guangdong Basic and Applied Basic Research Foundation(2019A1515011284);Guangzhou Basic and Applied Basic Research Foundation(202002030265).
This work demonstrates a smartphone-based automated fluorescence analysis system(SAFAS)for point-of-care testing(POCT)of Hg(Ⅱ).This system consists of three modules.The smartphone module is used to provide an excitat...
关键词:SMARTPHONE automated fluorescence detection cloth-based chip point-of-care testing Hg(II). 
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