Subjects funded by the National Natural Science Foundation of China(Nos.62275216 and 61775181);the Natural Science Basic Research Programme of Shaanxi Province-Major Basic Research Special Project(Nos.S2018-ZC-TD-0061 and TZ0393);the Special Project for the Development of National Key Scientific Instruments and Equipment No.(51927804).
Deep learning is capable of greatly promoting the progress of super-resolution imaging technology in terms of imaging and reconstruction speed,imaging resolution,and imagingflux.This paper proposes a deep neural netwo...
supported by the National Key Research and Development Program of China,Grant Number:2021YFF0502900,2019YFC1604604;National Natural Science Foundation of China,Grant Number:62075013,62027824.
Tumor vaccine therapy offers significant advantages over conventional treatments,including reduced toxic side effects.However,it currently functions primarily as an adjuvant treatment modality in clinical oncology due...
supported by the National Key R&D Program of China(No.2020YFA0710700);the National Natural Science Foundation of China(Nos.51873201 and 82172071);Key Research and Development Program of Anhui Province(No.202104b11020025);the Fundamental Research Funds for the Central Universities(No.YD2060002015);the CAS Youth Interdisciplinary Team(No.JCTD-2021-08).
In liver tumor surgery,the recognition of tumor margin and radical resection of microcancer focis have always been the crucial points to reduce postoperative recurrence of tumor.However,naked-eye inspection and palpat...
supported by the National Key R&D Program of China(2021ZD0201004);the National Natural Science Foundation of China(22165008,22077037,21474034,51673077 and 51603078);Hainan Provincial Natural Science Foundation of China(521RC506);the Open Project Program of Wuhan National Laboratory for Optoelectronics(No.2020WNLOKF018)。
Alzheimer's disease(AD)is a typical neurodegenerative disease.β-amyloid(AβÞplaque is the most prominent pathological biomarker associated with the progression of AD.Conventional Aβprobes,including commercial probe ...
work is funded by the National Natural Sci-ence Foundation of China(Grant/Award Numbers 62075135 and 61975126);Shenzhen Science and Technology Planning Project(ZDSYS2021-0623092006020);Key R&D Program of Shandong Province(Grant Number 2021CXGC010202);the Science and Technology Innovation Commission of Shenzhen(Grant/Award Numbers JCYJ201908-08174819083 and JCYJ20190808175201640)and Natural Science Foundation of Shandong Province(Grant Number ZR2022MA046);Major Innovation Projects for Integrating Science,Education&Industry of Qilu University of Technology(Shan-dong Academy of Sciences,Grant Number 2022JBZ01-04).
Multiphoton microscopy(MPM)is a powerful imaging technology for brain research.The imaging depth in MPM is partly determined by emission wavelength of fluorescent labels.It has been demonstrated that a longer emission...
supported by the Fundamental Re-search Funds for the Central Universities(HYGJXM202309).
The miniaturized femtosecond laser in near infrared-Ⅱregion is the core equipment of threephoton microscopy.In this paper,we design a compact and robust illumination source that emits dual-color linearly polarized li...
supported by the National Natural Science Foundation of China (62075066);Guangdong Basic and Applied Basic Research Foundation (2021A1515011285,2019A1515010800);Major Project under the Science and Technology Development Scheme of Guangdong Province (210715106900918,[2020]53-129);Shantou Science and Technology Plan Medical and Health Category Project (211114216492935).
Bioprobe based on fluorescence is widely used in biological and medical research due to its high sensitivity and selectivity.Yet,its quantification in vivo is complicated and often compromised by the interaction betwe...
This work is supported by the Key Project of the National Natural Science Foundation of China(Grant Number 62135003);the Science and Technology Program of Guangzhou(Grant No.202201010704);Special Carrier Program of Qingyuan Hitech Industrial Development Zone.
The automatic and accurate identification of apoptosis facilitates large-scale cell analysis.Most identification approaches using nucleus fluorescence imaging are based on specific morphological parameters.However,the...
supported by the National Natural Science Foundation of China (31700808);the Fundamental Research Funds for the Central Universities (2020kfyXJJS112).
Glioma is the most malignant brain cancer.The neurons,macrophages,T cells and other immune ellls constitute the glioma immunosuppressive microenvironment.The accurate spatial distri-bution of these cells in the glioma...
supported by the Guangdong Basic and Applied Basic Research Foundation(2019A1515011284);Guangzhou Basic and Applied Basic Research Foundation(202002030265).
This work demonstrates a smartphone-based automated fluorescence analysis system(SAFAS)for point-of-care testing(POCT)of Hg(Ⅱ).This system consists of three modules.The smartphone module is used to provide an excitat...