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作品数：816被引量：810H指数：11
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相关机构：华中科技大学重庆邮电大学中国科学院解放军信息工程大学更多>>
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Spatial transcriptomics combined with single-nucleus RNA sequencing reveals glial cell heterogeneity in the human spinal cord
《Neural Regeneration Research》2025年第11期3302-3316,共15页Yali Chen Yiyong Wei Jin Liu Tao Zhu Cheng Zhou Donghang Zhang 
supported by the National Natural Science Foundation of China,No.82301403(to DZ)。
Glial cells play crucial roles in regulating physiological and pathological functions,including sensation,the response to infection and acute injury,and chronic neurodegenerative disorders.Glial cells include astrocyt...
关键词：astrocyte glial cell HUMAN microglia oligodendrocyte sex differentiation single-nucleus RNA sequencing spatial transcriptomics species variation spinal cord 
Phosphodiesterase 9 localization in cytoplasm and nucleus:the gateway to selective targeting in neuroprotection?
《Neural Regeneration Research》2025年第6期1701-1702,共2页Giovanni Ribaudo Matteo Giannangeli Margrate Anyanwu Alessandra Gianoncelli 
The umbrella term"neurodege ne rative disorders"(NDDs) refers to several conditions characterized by a progressive loss of structure and function of cells belonging to the nervous system.Such diseases affect more than...
关键词：GATEWAY HOMEOSTASIS preserve 
Regulation of sleep by astrocytes in the hypothalamic ventrolateral preoptic nucleus
《Neural Regeneration Research》2025年第4期1098-1100,共3页Jae-Hong Kim Ruqayya Afridi Il-Sung Jang Maan Gee Lee Kyoungho Suk 
supported by a National Research Foundation of Korea(NRF)grant funded by the Korean government(2017R1A5A2015391 and 2020M3E5D9079764)(to KS).
Astrocytes are functionally dynamic cells that support neurons in multiple ways throughout an organism’s lifespan.The astrocytic regulation of neuronal activity has been increasingly recognized in recent years.Astroc...
关键词：SLEEP ventrolateral ASTROCYTES 
Single-nucleus RNA sequencing and spatial transcriptomics reveal the mechanism by which Xiaozhiling injection treats internal hemorrhoids
《World Journal of Gastrointestinal Surgery》2025年第4期333-346,共14页Min-Hui Ke Shu-Yan Huang Wei-Gan Lin Zhen-Guo Xu Xia-Xia Zheng Xian-Bao Liu You-Min Cheng Zuan-Fang Li 
Supported by the National Natural Science Foundation of China,No.81774118;the Foreign Cooperation Project of Science and Technology Department of Fujian Province,No.2023I0021;the Medical Innovation Project of Fujian Province,No.2024CXB013.
BACKGROUND Hemorrhoids,a prevalent chronic condition globally,significantly impact patients'quality of life.While various surgical interventions,such as external stripping and internal ligation,procedure for prolapse ...
关键词：Internal hemorrhoids Xiaozhiling injection FIBROBLAST Marker gene Single-cell sequencing Spatial transcriptome sequencing 
Evaluation of fission fragment moments of inertia forspontaneous fission of CF-252
《Chinese Physics C》2025年第3期95-106,共12页D.E.Lyubashevsky P.V.Kostryukov A.A.Pisklyukov J.D.Shcherbina 
In the present study,methods for estimating the moments of inertia of fission fragments resulting from the spontaneous fission of isotope Cf-252 were analyzed.In particular,two main approaches were examined:statistica...
关键词：properties of nuclei moment of inertia solid-state model superfluid model deformation of nucleus 
Integrating spatial transcriptomics and single-nucleus RNA-seq revealed the specific inhibitory effects of TGF-β on intramuscular fat deposition
《Science China(Life Sciences)》2025年第3期746-763,共18页Xiaoyu Wang Chuchu Chen Chenggan Li Xiaochang Chen Rong Xu Meilin Chen Yongpeng Li Yihao Liu Xiaohong Liu Yaosheng Chen Delin Mo 
supported by the National Natural Science Foundation of China(323B2058);Selection and Breeding of New Local Pig Breeds and Promotion of Industrialization(2022-440000-43010101-9501);Selection and Breeding of Guangdong Small-ear Spotted Pig(2022-440000-4301030202-9510);China Agriculture Research System(CASR-35);the Key Scientific Research Project of Education Department of Shaanxi(22JS033).
Intramuscular fat(IMF)is a complex adipose tissue within skeletal muscle,appearing specially tissue heterogeneous,and the factors influencing its formation remain unclear.In conditions such as diabetes,aging,and muscl...
关键词：intramuscular fat muscle atrophy spatial transcriptome single-nucleus RNA-seq TGF-Β 
Soft pattern of Rutherford scattering from heavy target mass expansion
《Chinese Physics C》2025年第3期17-27,共11页Yu Jia Jia-Yue Zhang 
Supported in part by the National Natural Science Foundation of China(11925506,12475090).
We investigate the soft behavior of the tree-level Rutherford scattering process.We consider two types of Rutherford scattering processes:One in which a low-energy massless point-like projectile(say,a spin-1/2 or spin...
关键词：Rutherford scattering nucleus structure heavy quark effective theory NRQED 
Properties of the drip-line nucleus and mass relation of mirror nuclei
《Nuclear Science and Techniques》2025年第2期112-122,共11页Meng-Ting Wan Li Ou Min Liu Ning Wang 
supported by the Ministry of Science and Technology of China(No.2022YFE0103400);Natural Science Foundation of Guangxi Province(No.2021GXNSFAA196052);National Natural Science Foundation of China(No.11965004).
The isospin asymmetry and quadrupole deformation value of drip-line nuclei are investigated using the Weizsäcker-Skyrme nuclear mass formula.We observe that for heavy nuclei at the neutron drip line,the Coulomb energy...
关键词：Nuclear mass formula Drip-line nucleus Magic number Mirror nuclei Coulomb energy 
Three-dimensional Heterogeneity and Intrinsic Plasticity of the Projection from the Cerebellar Interposed Nucleus to the Ventral Tegmental Area
《Neuroscience Bulletin》2025年第1期159-164,共6页Chen Wang Si-Yu Wang Kuang-Yi Ma Zhao-Xiang Wang Fang-Xiao Xu Zhi-Ying Wu Yan Gu Wei Chen Ying Shen Li-Da Su Lin Zhou 
supported by grants from the STI2030-Major Projects(2021ZD0204000);the Key Strategic Science and Technology Cooperation Project(2023YFE0206800);the Ministry of Science and Technology of China,the National Natural Science Foundation of China(31820103005,32170976,32100791,and 81971874),Zhejiang Province Natural Science Foundation of China(LZ24C090003 and LY21C090003);the Peak Discipline Cultivation Program of Zhejiang University School of Basic Medicine.
Dear Editor,In recent years,there has been an increasing focus on the non-motor functions of the cerebellum[1,2].Clinical observations have demonstrated that individuals with cerebellar damage exhibit affective insens...
关键词：attention COLLECTIVE damage 
Changes in the Mechanical Environment of the Nucleus with Cell Crowding and Its Effects on DNA Damage Resistance
《Journal of Biosciences and Medicines》2025年第1期230-242,共13页Kazuaki Nagayama Yuto Hirooka 
Nuclear DNA, which is essential for the transmission of genetic information, is constantly damaged by external stresses and is subsequently repaired by the removal of the damaged region, followed by resynthesis of the...
关键词：Cell Biomechanics MECHANOBIOLOGY Mechanical Properties DNA Damage γ-H2A.X 
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