目的:探究葡萄糖转运蛋白(glucose transporter,GLUT)1、GLUT2介导的葡萄糖摄取对小鼠牙齿早期发育的影响。方法:收集胚胎13.5 d(embryonic day 0.5,E13.5)、E14.5、E16.5、E18.5和出生后1 d(postnatal day 1,P1)时期的下颌磨牙牙胚、...
supported by the National Institute of General Medical Sciences of the National Institutes of Health under award number R35GM118041.
CYP3A5 is a cytochrome P450(CYP)enzyme that metabolizes drugs and contributes to drug resistance in cancer.However,it remains unclear whether CYP3A5 directly influences cancer progression.In this report,we demonstrate...
supported by the National Natural Science Foundation of China(62175198,52273114,82103323,82003992,and U22A2092);the Fundamental Research Funds for the Central Universities(xtr062022002);Key Research and Development Program of Shaanxi Province under Grant No.2022ZDLSF04-09;Beijing Natural Science Foundation(7222214).
Systematic administration of small molecular drugs often suffered from the low efficacy and systemic toxicity in cancer therapy.In addition,application of single mode drug usually leads to unsatisfactory therapeutic o...