supported by grants from the Ministry of Science and Technology of China(2018YFA0801100 and 2021YFF0702100);the National Natural Science Foundation of China(31971056,31772550,and 32000513);the Natural Science Foundation of Jiangsu Province(BK20181260);the Fundamental Research Funds for the Central Universities(14380516 and 021414380533).
Homeostasis of the skin barrier is essential for maintaining normal skin function.Gasdermin A(GSDMA)is highly expressed in the skin and associated with many skin diseases,such as melanoma and psoriasis.In mice,GSDMA i...