The mechanisms determining persistence of hepatitis B virus (HBV) infection and long-term pathogenesis of HBV-associated liver disease appear to be multifactorial.Although viral replication can be efficiently suppress...
Supported by National Health Research Institutes (NHRI-EX94-9412EI); VTY Joint Research Program, Tsou's Foundation (VGHUST94-P6-32)
AIM: To study the baculovirus/mammalian cell system for efficient expression of functional large hepatitis delta antigen (L-HDAg). METHODS: A recombinant baculovirus expressing histidine-tagged L-HDAg (L-HDAgH) ...