This study was supported by the Spanish Ministry of Science,Innovation and Universities(No.AGL2014-57752-C2-2R and RTI2018-094350-B-C32);ALG was recipient of a PhD grant from the Spanish Ministry(grant BES-2015-071369).
Baculoviruses constitute a large group of invertebrate DNA viruses, predominantly infecting larvae of the insect order Lepidoptera. During a baculovirus infection, the virus spreads throughout the insect body producin...
This work was supported by the grants from the National Science Foundation of China(Grant Nos.31800143 and 31872640);the Key Research Program of Frontier Sciences of the Chinese Academy of Sciences(Grant No.QYZDJ-SSW-SMC021);the Hubei Provincial Innovation Center of Agricultural Sciences and Technology(Grant No.2019-620-000-001-017)。
Baculoviruses are large DNA viruses which have been widely used as expression vectors and biological insecticides.Homologous recombination and Bac-to-Bac system have been the main methods for manipulating the baculovi...
supported by grants from National Key Plan for Scientific Research and Development of China(2019YFC1200504);National Natural Science Foundation of China(grant numbers 31621061 and 31872298);Open Research Fund Program of State Key Laboratory of Integrated Management of Pest Insects and Rodents(Chinese IPM2015).
Baculoviruses are natural enemies of agricultural and forest insect pests and play an important role in biological pest control.Oral infection by baculovirus in the insect midgut is necessary for establishing systemic...
the United States Department of Agriculture(AFRI 2017-67013-26596)awarded to GWF and KH;National Science Foundation(IOS-1645548)awarded to GWF,IS,and KH;and Hatch Project PEN04576(GWF and KH).QP thanks the financial support from China Scholarship Council(grant 201506300111);Natural Sciences and Engineering Research Council of Canada Postdoctoral Fellowship(NSERC PDF-488105-2016).
Insects possess specific immune responses to protect themselves from different types of pathogens.Activation of immune cascades can inflict significant developmental costs on the surviving host.To characterize infecti...
supported by grants from the National Key R&D Program of China(2016YFD0500406);the National Natural Science Foundation of China(NSFC)(no.81672036);the Youth Innovation Promotion Association of CAS(2016302)
Zika virus(ZIKV)is emerging as a significant pathogen worldwide and may cause severe neurological disorders such as fetal microcephaly and Guillain-Barre syndrome.No drug or listed vaccines are currently available for...
This work was funded by National Natural Science Foundation of China(No.31602009,31572466 and 31472152);Fundamental Research Funds for the Central Universities(SWU116066 and XDJK2018C009),China Agriculture Research System(CARS-18),China Postdoctoral Science Foundation(2015M582502);Chongqing Postdoctoral Science Foundation(Xm2015121).
As an important insect immune response,apoptosis plays a critical role in the interaction between baculoviruses and insect hosts.Previous reports have identified inhibitor of apoptosis(IAP)proteins in both insects and...
supported by the grants from the Key Research Project of Frontier Science (QYZDJ-SSWSMC021);the Strategic Priority Research Program (grant No. XDB11030400) from the Chinese Academy of Sciences;the grants (No. 31621061) from the National Natural Science Foundation of China
Baculoviridae is a family of large DNA viruses that specifically infect insects. It contains four genera, Alpha-, Beta-,Gamma-, and Deltabaculovirus. Alphabaculovirus is further divided into Group Ⅰ and Ⅱ, and Group...
supported by the National Natural Science Foundation of China (31572056 and 31872025);the Key Project of Natural Science Foundation of Guangdong Province (2018B030311018);the National Key R&D Program of China (2017YFD0200404);the Guangzhou Science and Technology Project (201707020003)
Our previous study has shown that the Autographa californica multiple nucleopolyhedrovirus(AcMNPV) p48(ac103)gene is essential for the nuclear egress of nucleocapsids and the formation of occlusion-derived virions(ODV...
supported by the National Key Research and Development Program of China (2016YFD0500801)
Hepatitis-hydropericardium syndrome(HHS)is an infectious disease caused by fowl adenovirus serotype 4(FAdV-4).Several structural and non-structural proteins of FAdV-4 have been expressed in Escherichia coli and baculo...
Baculoviruses infect insects in nature by targeting their larvae.They can also pass on genes into mammalian cells(including human cells)without producing progeny viruses via a process termed transduction.For that,they...