funded by the National Key Research and Development Program of China(Grant number 2022YFD1400700);Initiative Scientific Research Program,Institute of Zoology,Chinese Academy of Sciences(Grant number 2023IOZ010).
Spodoptera frugiperda multiple nucleopolyhedrovirus(SfMNPV),belonging to the species Alphabaculovirus spofrugiperdae,has been recently registered as an insecticide in China.This virus has a specific effect on the glob...
supported by Guangzhou Science and Technology Plan(202201010369);Natural Science Foundation of Guangdong Basic and Applied Basic Research Fund(2022A1515012657);National Natural Science Foundation of China(31872426);South China Agricultural University high-level talent launch project;and Guangdong Provincial Promotion Project on Preservation and Utilization of Local Breed of Livestock and Poultry(No.2018-143).
The Piwi-interacting RNA(piRNA)pathway has been shown to be involved in the antiviral defense against RNA viruses,especially in mosquitoes,but its universality has been questioned.Here,we used the Bombyx mori nucleopo...
funded by National Natural Science Foundation of China(31972333);Shandong Provincial Natural Science Foundation(ZR2020MC128,ZR2020MC130);Basic Research Project of Shenzhen Municipal Science and Technology Innovation Committee(JCYJ20190813144407666).
Peptidoglycan recognition proteins(PGRPs)are a class of molecules that play a critical role in insect immunity.Understanding the function of PGRPs is important to improve the efficiency of microbial insecticides.In th...
funded by the Natural Science Foundation of Shanxi Province,Grant No.201801D121193;the Central Government Guiding Local Science and Technology Development Fund Project,Grant No.YDZJSX2022A001.
Background:The immune system of insects exerts fundamentally different antiviral mechanisms than mammals.MicroRNAs(miRNAs)play vital roles in developing insect antiviral immunity.MiRNAs expression profiles of insects ...
This work was supported by the grants from the National Science Foundation of China(Grant Nos.31800143 and 31872640);the Key Research Program of Frontier Sciences of the Chinese Academy of Sciences(Grant No.QYZDJ-SSW-SMC021);the Hubei Provincial Innovation Center of Agricultural Sciences and Technology(Grant No.2019-620-000-001-017)。
Baculoviruses are large DNA viruses which have been widely used as expression vectors and biological insecticides.Homologous recombination and Bac-to-Bac system have been the main methods for manipulating the baculovi...
supported by the National Key Research and Development Program of China(2017YFD0201206);the WIV “One-Three-Five”strategic program(Y602111SA1 to XS)。
Autographa californica multiple nucleopolyhedrovirus(Ac MNPV)orf13(ac13)is a conserved gene in all sequenced alphabaculoviruses.However,its function in the viral life cycle remains unknown.In this study,we found that ...
This research was supported by the grants from the National Natural Science Foundation of China(No.31872640);the Key Research Program of Frontier Sciences of the Chinese Academy of Sciences(grant no.QYZDJ-SSW-SMC021);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB11030400).
Baculoviruses have been widely used as a vector for expressing foreign genes.Among numerous baculoviruses,Autographa californica multiple nucleopolyhedrovirus(AcMNPV)is the most frequently used and it encodes 155 open...
the United States Department of Agriculture(AFRI 2017-67013-26596)awarded to GWF and KH;National Science Foundation(IOS-1645548)awarded to GWF,IS,and KH;and Hatch Project PEN04576(GWF and KH).QP thanks the financial support from China Scholarship Council(grant 201506300111);Natural Sciences and Engineering Research Council of Canada Postdoctoral Fellowship(NSERC PDF-488105-2016).
Insects possess specific immune responses to protect themselves from different types of pathogens.Activation of immune cascades can inflict significant developmental costs on the surviving host.To characterize infecti...
This work was supported by the National Natural Science Foundation of China(Nos.31472153 and 31872427);the China Agriculture Research System(CARS-18).
Ser/Thr protein phosphatase 2A(PP2A)is one of the type 2 protein phosphatases,which is required for many intracellular physiological processes and pathogen infection.However,the function of PP2A is unclear in silkworm...
This work was funded by National Natural Science Foundation of China(No.31602009,31572466 and 31472152);Fundamental Research Funds for the Central Universities(SWU116066 and XDJK2018C009),China Agriculture Research System(CARS-18),China Postdoctoral Science Foundation(2015M582502);Chongqing Postdoctoral Science Foundation(Xm2015121).
As an important insect immune response,apoptosis plays a critical role in the interaction between baculoviruses and insect hosts.Previous reports have identified inhibitor of apoptosis(IAP)proteins in both insects and...