HERPES

作品数：143被引量：222H指数：7
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相关机构：第三军医大学西南医院海盐县人民医院广州中医药大学四会市中医院更多>>
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Transcriptional regulation of the Herpes Simplex Virus 1α-gene by the viral immediate-early protein ICP22 in association with VP16被引量：4
《Science China(Life Sciences)》2009年第4期344-351,共8页CUN Wei, GUO Lei, ZHANG Ying, LIU LongDing, WANG LiChun, LI JianFeng, DONG ChengHong, WANG JinJin & LI QiHan Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650118, China 
Supported by the National Natural Science Foundation (Grant No. 30570081, 30670094);Doctoral Fund of Ministry of Education of China (Grant No. 20060023053)
Herpes Simplex Virus 1 (HSV1) is capable of inducing two forms of infection in individuals, and the establishment of which type of infection occurs is linked to the transcriptional activation of viral α genes. One of...
关键词：HERPES SIMPLEX virus ICP22 transcription VP16 α GENE 
Functional analysis of transcriptional regulation of herpes simplex virus type 1 tegument protein VP22被引量：4
《Science China(Life Sciences)》2008年第11期966-972,共7页YU Xian1,2, LI WeiZhong1, LIU LongDing1, CHE YanChun1, CUN Wei1, WU WenJuan1, HE ChunYan1, SHAO CongWen1 & LI QiHan1 1 Department of Viral Immunology, Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650118, China 2 Institute of Materia Medica, North Sichuan Medical College, Nanchong 637007, China 
the National Natural Science Foundation of China (Grant Nos. 30570081,30670094 and 30700028)
The herpes simplex virus type 1 (HSV-1) tegument proteins have important functions in the viral repli- cation process. In order to investigate the role of the HSV-1 tegument protein VP22 in viral replication, its tran...
关键词：HERPES SIMPLEX virus type 1 TEGUMENT VP22 TRANSCRIPTIONAL regulation 
A novel and highly efficient production system for recombinant adeno-associated virus vector被引量：10
《Science China(Life Sciences)》2002年第1期96-104,共9页伍志坚 吴小兵 曹晖 董小岩 王宏 侯云德 
This work was supported by the National High Technology Development Program.
Recombinant adeno-associated virus(rAAV) has proven to be a promising gene delivery vector for human gene therapy. However, its application has been limited by difficulty in obtaining enough quantities of high-titer v...
关键词：RECOMBINANT ADENO-ASSOCIATED virus(rAAV)  RECOMBINANT HERPES simplex VIRUS type 1(rHSV-1)  vector  gene therapy  production system  green fluorescent protein(GFP). 
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