supported by the National Natural Science Foundation of China(Grant No.32171895);National Key Research and Development Program for Young Scientists,China(Grant No.2022YFD2000200);Jiangsu Province Key Reserch and Development Program Project,China(Grant No.BE2022052-2).
Rapid diagnosis of rice bacterial diseases is critical for early warning and precise management during their initial phases.The use of rapid nucleic acid detection on paper-based platforms is an innovative technique t...
Background Recombinant human GH(rhGH)was first approved to treat children with growth hormone deficiency(GHD)by Food and Drug Administration(FDA)in the United States in 1985.The indications subsequently expanded to gr...
supported by National Key R&D Program of China(Grant No.2022YFC2401800);National Natural Science Foundation of China(Grant No.32301116);Sichuan Science and Technology Program(Grant No.2023NSFSC0996)
The objective of regenerative wound healing dressings is to accelerate skin tissue regeneration and restore normal physiological function at wound sites.Achieving this goal requires biomaterials capable of repairing d...
supported by grants from the National Natural Science Foundation of China(grant nos.22074057,21775059 and 21305056)
The reconstruction of critical-size calvarial defects remains a fundamental challenge.Recombinant collagen has gained significant attention in bone tissue engineering owing to its remarkable bioactivity and non-immuno...
In the past decade,there has been increasing interest in whether a widespread childhood varicella immunization scheme may increase the age-specific incidence of herpes zoster in adults.This proposition is based on evi...
supported by the"Open Bidding for Selecting the Best Candidates"Program of Taiyuan(2024TYJB0149).
Collagen is the most abundant protein in mammals.Based on the source,collagen can be categorized into human and non-human-derived collagen,while the recombinant collagen is divided into recombinant human collagen,reco...
supported by the National Key Research and Development Program of China(2022YFC2304100 and 2021YFA1201003).
Viral infectious clones(ICs)serve as robust platforms for studying viral biology and screening antiviral agents using reverse genetics.However,the molecular profiles and complex limitations of human coronaviruses(HCoV...
supported by National Key Research and Development Program of China(2023YFA0913700);National Natural Science Foundation of China(82073858,82173821,82273934,and 82373875);Natural Science Foundation of Shanghai(21ZR1432700);the open project of Anhui Province Key Laboratory of Translational Acta Pharmacologica Sinica(2024)45:2646-2656 Cancer Research(KFKT202302);Anhui Province Scientific Research Compilation Plan Project(2022AH040214);Anhui Province Translational Special Project for Clinical Medical Research(202204295107020038);Shanghai Society of Biotechnology(SSBT);Key Research and Development Projects in Anhui Province for A(202104j07020021)。
Recombinant human type 5 adenovirus(H101)is an oncolytic virus used to treat nasopharyngeal carcinoma.Owing to the deletion of the E1B-55kD and E3 regions,H101 is believed to selectively inhibit nasopharyngeal carcino...
the National Natural Science Foundation of China(Nos.52273128,82003450);the Natural Science Foundation of Guangdong Province(No.2022A1515220048);the Natural Science Foundation of Guizhou Province(Nos.Guizhou Province-ZK[2022]General 300,Guizhou Province-ZK[2023]General 244);the Xiangshan Talented Scientific Research Foundation of Zhuhai People’s Hospital(No.2023XSYC-01);Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment(No.2021B1212040004)。
Developing natural nano-platforms with high biocompatibility and natural targeting ability represents great significance for drug delivery.High-density lipoprotein(HDL),a natural lipid-protein complex,plays important ...
Supported by the National Natural Science Foundation of China(82160635);the Yunnan Revitalization Talents Support Program(Special Project for Famous Doctors).
What is already known about this topic?Recombinant strains dominate the human immunodeficiency virus 1(HIV-1)epidemic in China.Yunnan Province was the first region in China to report HIV-1 infections in batches.The lo...