This work was supported by the grants from the National Natural Science Foundation of China(Nos.U21A20343,82171682,and 82270492);the Natural Science Foundation of Ningxia Hui Autonomous Region(No.2020AAC02038);the Key Research and Development Projects in Ningxia Hui Autonomous Region(Nos.2019BFG02004,2021BEG02028,2020BEG03005,2020BFH02003,and 2022BEG02054);the Basic Scientific Research Operating Expenses from the public welfare research institutes at the central level of the Chinese Academy of Medical Sciences(No.2019PT330002).
Accumulating evidence has shown that the apoptosis of trophoblast cells plays an important role in the pathogenesis of preeclampsia,and an intricate interplay between DNA methylation and polycomb group(PcG)proteinmedi...