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作品数：309被引量：946H指数：15
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Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair被引量：14
《Bioactive Materials》2023年第6期477-496,共20页Han Sun Juan Xu Yangyufan Wang Siyu Shen Xingquan Xu Lei Zhang Qing Jiang 
supported by National Science Foundation of China(Grant No.32271409,82002370,31800806);National Basic Research Program of China(2021YFA1201404);China Postdoctoral Science Foundation(Grant No.2019M661806);Major Project of NSFC(81991514);Natural Science Foundation of Jiangsu Province(Grant No.BK20200117);Jiangsu postdoctoral research support project(Grant No.2021K059A);Program of Innovation and Entrepreneurship of Jiangsu Province,Jiangsu Provincial Key Medical Center Foundation,Jiangsu Provincial Medical Outstanding Talent Foundation,Jiangsu Provincial Medical Youth Talent Foundation and Jiangsu Provincial Key Medical Talent Foundation,the Fundamental Research Funds for the Central Universities(14380493,14380494);Changzhou Sci&Tech Program(Grant No.CJ20220103).
Large bone defects resulting from fractures and disease are a major clinical challenge,being often unable to heal spontaneously by the body’s repair mechanisms.Lines of evidence have shown that hypoxia-induced overpr...
关键词：Bone defect Hypoxic microenvironment Reactive oxygen species responsiveness Prolonged oxygen generation Brain and muscle arnt-like protein 1 
Molecular characterization of organic matter transformation mediated by microorganisms under anoxic/hypoxic conditions被引量：1
《Science China Earth Sciences》2023年第4期894-909,共16页Shicong XIAO Jiaxin CHEN Yuan SHEN Qi CHEN Yu WANG Yunyun LI Chen HE Ruanhong CAI Quan SHI Nianzhi JIAO Qiang ZHENG 
supported by the National Key Research and Development Project of the Ministry of Science and Technology of China(Grant No.2021QZKK0102);the National Natural Science Foundation of China(Grant Nos.42222604,42188102,92251306,42141003,41861144018 and 42106040);the President’s Fund of Xiamen University(Grant Nos.20720170107 and 20720210076)。
Dissolved organic matter(DOM) in the ocean is one of the largest carbon pools on Earth. Microbial metabolism is an important process that shapes the marine DOM pool. Current studies on the interactions between microor...
关键词：Anoxic/hypoxic Microbial community structure Dissolved organic matter Chemical characteristics of molecule 
WIP1 Phosphatase Plays a Critical Neuroprotective Role in Brain Injury Induced by High-Altitude Hypoxic Inflammation被引量：10
《Neuroscience Bulletin》2017年第3期292-298,共7页Dahu Li Lijun Zhang Xin Huang Lili Liu Yunling He Lun Xu Yiyao Zhang Tong Zhao Liying Wu Yongqi Zhao Kuiwu Wu Yan Wu Ming Fan Lingling Zhu 
supported by the National Natural Science Foundation of China(31401000 and 81430044);the Youth Medicine Program of the People’s Liberation Army of China(13QNP148);the National Basic Research Development Program(973 Program)of China(2012CB518200);the Integrated Drug Discovery Technology Platform of National Science and Technology Major Projects for‘‘Major New Drugs Innovation and Development’’,China(2012ZX09J12201-005)
The hypobaric hypoxic environment in highaltitude areas often aggravates the severity of inflammation and induces brain injury as a consequence. However, the critical genes regulating this process remain largely unkno...
关键词：Hypobaric hypoxia Inflammation Brain injury WIP1 phosphatase Lipopolysaccharide 
Mechanisms leading to the frequent occurrences of hypoxia and a preliminary analysis of the associated acidification off the Changiiang estuary in summer被引量：7
《Science China Earth Sciences》2017年第2期360-381,共22页WEI QinSheng WANG BaoDong YU ZhiGang CHEN JianFang XUE Liang 
supported by the National Natural Science Foundation of China(Grant Nos.41206068&41620104001);the National Natural Science Foundation-Shandong Province Joint Fund for Marine Science Research Center(Grant No.U1406403);the Basic Scientific Fund for National Public Research Institutes of China(Grant No.2016S/Q08);the Open Fund of the Key Laboratory of Marine Ecology and Environmental Sciences,Institute of Oceanology,Chinese Academy of Sciences and the Laboratory of Marine Ecology and Environmental Science;Qingdao National Laboratory for Marine Science and Technology(Grant No.KLMEES201603);the National Basic Research Program of China(Grant No.2010CB428703);the National Project of Comprehensive Investigation and Research of the Coastal Seas of China(Grant No.908-ZC-I-03)
Based on literature data and shipboard observations,this study investigated the main environmental characteristics of the seafloor topography,current field,front,and upwelling that are closely related to hypoxia occur...
关键词：Changjiang estuary Hypoxic zone UPWELLING Front Nutrient regeneration BIOGEOCHEMISTRY ACIDIFICATION 
Recognition on the forming-vanishing process and underlying mechanisms of the hypoxia off the Yangtze River estuary被引量：17
《Science China Earth Sciences》2015年第4期628-648,共21页WEI QinSheng WANG BaoDong CHEN JianFang XIA ChangShui QU DaPeng XIE LinPing 
supported by the National Natural Science Foundation of China(Grant No.41206068);the National Ocean Public Welfare Scientific Research Project of China(Grant No.201105014);the National Basic Research Program of China(Grant Nos.2010CB429004,2010CB951900);the National Project of Comprehensive Survey and Assessment of the Coastal Seas of China(Grant No.908-ZC-I-03);the National Key Technology Research and Development Program of China(Grant No.2008BAC42B02)
On the basis of compiled multidisciplinary historical data in 2006-2007 and incorporation of relevant simulation results and re- mote sensing data, we performed an in-depth study of the generation and dissipation proc...
关键词：Yangtze River estuary hypoxic zone STRATIFICATION flow field environment organic decomposition 
A necklace of pearl in high altitude medicine and hypoxic physiology in Yushu Earthquake被引量：3
《Engineering Sciences》2013年第2期2-4,共3页Fan Ming 
"973"National Key Basic Research and Development Program(No.2012CB518202)
During Yushu Earthquake,a large number of rescuers flocked to the mountainous quake areas. Under such a very specific circumstance,a high incidence of acute altitude illness was observed in rescuers who rapidly travel...
关键词：Yushu Earthquake 973 Project acute altitude illness learn by experiences and lessons 
Fish assemblage structure in the hypoxic zone in the Changjiang (Yangtze River) estuary and its adjacent waters被引量：1
《Chinese Journal of Oceanology and Limnology》2010年第3期459-469,共11页单秀娟 金显仕 袁伟 
Supported by the National Natural Science Foundation of China (No. 30490233, 40906086);the National Basic Research Program of China (973 Program) (No. 2006CB400608);Taishan Scholar Program of Shandong Province, Postdoctoral creative foundation of Shandong Province and the Yellow & Bohai Sea Scientific Observation and Experiment Station for Fishery Resources and Environment, Ministry of Agriculture
Fish assemblage structure in the hypoxic zone in the Changjiang (Yangtze River) estuary and its adjacent waters were analyzed based on data from bottom trawl surveys conducted on the R/V Beidou in June, August and Oct...
关键词：the Changjiang estuary fish assemblage structure diversity size spectrum 
Characteristics of fat metabolism in skeletal muscle of rats after hypobaric hypoxic acclimation被引量：2
《Journal of Medical Colleges of PLA(China)》2008年第5期258-262,共5页Mao Sunzhong Gao Yuqi Chen Jian Liu Fuyi Gao Wenxiang Huang Jian Liao Weigong Cai Mingchun 
the National Basic Research Program of China(2006CB504100);the National Natural Science Foundation of China (30393131, 30771043)
Objective：To investigate the characteristics of fat metabolism in rat skeletal muscle after hypobaric hypoxia acclimation. Methods： Sprague-Dawley rats were divided into 3 groups randomly： control group （H0）, hyp...
关键词：Energy metabolism Hypobaric hypoxia ACCLIMATION FAT 
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