IKVAV

作品数:25被引量:40H指数:4
导出分析报告
相关领域:医药卫生更多>>
相关作者:郑启新宋玉林吴永超吴斌郭晓东更多>>
相关机构:华中科技大学南昌大学第二附属医院新疆医科大学青岛大学更多>>
相关期刊:《Journal of Wuhan University of Technology(Materials Science)》《Regenerative Biomaterials》《中华创伤骨科杂志》《中国脊柱脊髓杂志》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金新疆维吾尔自治区自然科学基金更多>>
-

检索结果分析

结果分析中...
条 记 录,以下是1-10
视图:
排序:
Functional self-assembling peptide nanofiber hydrogel for peripheral nerve regeneration被引量:7
《Regenerative Biomaterials》2017年第1期21-30,共10页Xiaoli Wu Liumin He Wen Li Heng Li Wai-Man Wong Seeram Ramakrishna Wutian Wu 
The authors thank for funding supports from the National Program on Key Basic Research Project(973 Program,2014CB542205);Hong Kong RGC grant(17124514);Foundation for Distinguished Young Talents in Higher Education of Guangdong(Yq2013023);Pearl River Nova Program of Guangzhou(2014J2200001);China Postdoctoral Science Foundation(2013M540684);the Leading Talents of Guangdong Province(87014002);National Natural Science Foundation of China(51103062);The authors wish to acknowledge the support from the Hong Kong Scholars Program(XJ2012024).
Peripheral nerves are fragile and easily damaged,usually resulting in nervous tissue loss,motor and sensory function loss.Advances in neuroscience and engineering have been significantly contributing to bridge the dam...
关键词:Peripheral nerve regeneration self-assembling peptide IKVAV RGD nanofibrous hydrogel 
大鼠骨髓间充质干细胞与树枝状两亲性多肽自组装凝胶支架的生物相容性被引量:2
《西安交通大学学报(医学版)》2016年第6期803-809,共7页陈睿 宋玉林 汪文玉 吴凯 陈伟高 
国家自然科学基金资助项目(No.81360271);江西省教育厅科学技术研究重点项目(No.GJJ14054)~~
目的 研究大鼠骨髓间充质干细胞(bone marrow mesenchymal stem cells,BMSCs)与树枝状两亲性多肽自组装凝胶支架的生物相容性。方法 获取大鼠BMSCs,传至第3代行流式细胞术表面抗原检测及成脂分化诱导鉴定干细胞。设计含双链-IKVAV活...
关键词:骨髓间充质干细胞 -IKVAV 树枝状两亲性多肽 细胞相容性 
Adhesive peptides conjugated PAMAM dendrimer as a coating polymeric material enhancing cell responses被引量:1
《Chinese Chemical Letters》2016年第9期1473-1478,共6页Panita Maturavongsadit Xiangdong Bi Togor A. Gado Yu-Zhe Nie Qian Wang 
financially supported by the NSF-ECCS 1509760;NSF EPSCoR RII Track 1 cooperative agreement awarded to the University of South Carolina (NSF EPSCoR Cooperative Agreement No. EPS-0903795)
This present work aims to functionalize poly(amidoamine) (PAMAM) dendrimers with various reported adhesive peptides, including Arg-Gly-Asp (RGD), Tyr-lle-Gly-Ser-Arg (YIGSR), and Ile-Lys-Val-Ala-Val (IKVAV) ...
关键词:PAMAM dendrimer RGD peptide YIGSR peptide IKVAV peptide Bone marrow mesenchymal stem cells PC12 cells 
Cytocompatibility Evaluation of Grafted IKVAV PLEOF Hydrogels with Bone Marrow Mesenchymal Stem Cells被引量:1
《Journal of Wuhan University of Technology(Materials Science)》2014年第4期824-831,共8页李宾斌 ZHANG Ping YIN Yixia QIU Tong TAO Yuan WANG Xinyu 李世普 
Funded by theNational Basic Research Program of China(No.2011CB606205);the Self-determined and Innovative Research Funds of WUT(No.2012-YB-007)
The novel hydrogels-grafted IKVAV poly(lactide-co-ethylene oxide-co-fumarate)(PLEOF) hydrogels(GIPHs) were developed. The rat bone marrow mesenchymal stem cells(BMMSCs) were employed, and the cell vitality and...
关键词:proliferation IKVAV hydrogels vitality apoptosis 
神经干细胞联合体外自组装IKVAV纳米纤维凝胶移植治疗大鼠脊髓损伤被引量:3
《中华医学杂志》2013年第21期1669-1673,共5页阚瑞 涂来勇 杨明坤 徐韬 马艳 毕晓娟 盛伟斌 
新疆维吾尔自治区自然科学基金(2011211A059)
目的观察神经干细胞(NSC)联合自组装IKVAV纳米纤维凝胶移植促进大鼠脊髓损伤的修复。方法SD大鼠230只,随机分为凝胶治疗组、NSC治疗组、NSC联合自组装IKVAV纳米纤维凝胶移植治疗组、生理盐水治疗组和假手术组。分别于术后第1、3、5、...
关键词:脊髓损伤 神经干细胞 IKVAV 
人工合成IKVAV多肽对星形胶质细胞增殖和Neurocan基因表达的影响被引量:1
《脊柱外科杂志》2012年第2期109-112,共4页王天瑞 马学晓 于腾波 相宏飞 陈伯华 
山东省青年科学家研究奖励基金(2007BS03047);青岛市科技发展计划(06-2-2-6 nsh-2)
目的观察人工合成IKVAV多肽对星形胶质细胞增殖及硫酸软骨素蛋白多糖核心蛋白Neurocan基因表达的影响,并探讨IKVAV潜在的促进受损脊髓功能恢复的作用。方法设计IKVAV序列,人工合成IKVAV多肽,将星形胶质细胞接种于1%IKVAV包被的培养板上...
关键词:肽类 星形细胞 基因表达 细胞增殖 脊髓损伤 
体外自组装IKVAV纳米纤维凝胶在二维体系中对神经祖细胞分化的影响被引量:1
《中国组织工程研究与临床康复》2011年第8期1409-1412,共4页扈佃磊 于圣会 刘宁 盛伟斌 郭海龙 马艳 毕晓娟 
新疆医科大学第一附属医院青年专项基金项目(20009QN06)~~
背景:大量实验证明体外自组装的纳米支架材料可以促进神经祖细胞增殖与分化。目的:观察体外自组装含IKVAV纳米纤维凝胶在二维体系中对神经祖细胞分化的影响。方法:培养SD大鼠乳鼠神经祖细胞并用免疫荧光方法鉴定。在DMEM/F12触发下,...
关键词:神经祖细胞 纳米支架 IKVAV 纳米纤维凝胶 生物材料与纳米技术 
Effect of IKVAV Peptide Nanofiber on Proliferation,Adhesion and Differentiation into Neurocytes of Bone Marrow Stromal Cells被引量:2
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2010年第2期178-182,共5页吴斌 郑启新 吴永超 郭晓东 邹枕玮 
supported by grants from the National Natural Sciences Foundation of China (No. 30500511);the National High-tech Research Program (No. 2006AA320 605)
This study examined the effect of IKVAV peptide nanofiber on proliferation, adhesion and differentiation into neurocytes of bone marrow stromal cells (BMSCs). IKVAV Peptide-amphiphile was synthesized and purified. T...
关键词:bone marrow stem ceils IKVAV SELF-ASSEMBLY nerve tissue engineering 
Cytocompatibility of Self-assembled Hydrogel from IKVAV-containing Peptide Amphiphile with Neural Stem Cells
《Journal of Wuhan University of Technology(Materials Science)》2009年第5期753-756,共4页宋玉林 
Neural Stem Cells (NSCs) were incubated with self-assembled hydrogel from IKVAV-containing peptide amphiphile (IKVAV-PA) for one week. The cytocompatibility of hydrogel was evaluated. NSCs were seeded in three-dim...
关键词:IKVAV HYDROGEL CYTOCOMPATIBILITY proliferation 
含IKVAV两亲性肽自组装凝胶二维诱导神经干细胞的分化
《中国组织工程研究与临床康复》2009年第34期6667-6670,共4页宋玉林 郑启新 吴凯 殷明 
背景:脊髓基质支架是构建脊髓组织工程的关键因素,目前,各种无机或有机高分子材料均不是构建脊髓组织工程理想支架材料,含有活性结构的多肽在体液或培养液促发下可形成与脊髓黏弹性一致多孔支架,有望成为优良脊髓组织工程支架材料。目的...
关键词:神经干细胞 分化 自组装 凝胶 
检索报告 对象比较 聚类工具 使用帮助 返回顶部