INSULIN_RESISTANCE

作品数:784被引量:3615H指数:25
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相关作者:李雪飞张思仲刘合焜陈素云田浩明更多>>
相关机构:南京医科大学北京大学第一医院北京大学四川大学华西医院更多>>
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Understanding the link between type 2 diabetes mellitus and Parkinson's disease:role of brain insulin resistance
《Neural Regeneration Research》2025年第11期3113-3123,共11页Theodora Ntetsika Sergiu-Bogdan Catrina Ioanna Markaki 
support from Region Stockholm,ALF-project(FoUI-960041);Open Access funding is provided by Karolinska Institute(both to IM)。
Type 2 diabetes mellitus and Parkinson's disease are chronic diseases linked to a growing pandemic that affects older adults and causes significant socio-economic burden.Epidemiological data supporting a close relatio...
关键词:brain insulin resistance brain insulin signaling diabetes type 2 GLP-1 receptor agonists GLP-1 signaling insulin resistance insulin signaling NEURODEGENERATION Parkinson's disease targeted therapy 
Immunosuppressive agents in diabetes treatment:Hope or despair?
《World Journal of Diabetes》2025年第5期89-108,共20页Lu Li Xi Yang Jin-Shuai Ren Ming-Zhu Huang Qing-Wei Zhao 
Supported by The National Natural Science Foundation of China,No.82273986;Natural Science Foundation of Zhejiang Province,No.LYY22H310014.
Exploration of immunosuppressive agents for the treatment of diabetes is a burgeoning field that has captured the attention of the medical community.The innovative approach of using these agents to combat diabetes is ...
关键词:Immunosuppressive agents Type 1 diabetes Type 2 diabetes Insulin resistance TRANSPLANTATION 
Comparisons of various insulin resistance indices for new-onset metabolic syndrome before midlife:The CHIEF cohort study,2014-2020
《World Journal of Diabetes》2025年第5期192-201,共10页Wei-Nung Liu Yi-Chiung Hsu Yen-Po Lin Kun-Zhe Tsai Yen-Chen Lin Pang-Yen Liu Gen-Min Lin 
Supported by Medical Affairs Bureau Ministry of National Defense,No.MND-MAB-D-114222;Hualien Armed Forces General Hospital,No.HAFGH-D-114008.
BACKGROUND Some non-insulin-based insulin resistance(IR)indices have been found to be associated with metabolic syndrome(MetS);however,few cohort studies have compared the capacities of these indices for predicting in...
关键词:Cohort study Insulin resistance indices Metabolic syndrome Young adults 
Neurophysiological mechanisms of electroacupuncture in regulating pancreatic function and adipose tissue expansion
《World Journal of Diabetes》2025年第5期254-270,共17页Yun Liu Zhi Yu Xuan Wang Ming-Qian Yuan Meng-Jiang Lu Mei-Rong Gong Qian Li You-Bing Xia Guan-Hu Yang Bin Xu Gerhard Litscher Tian-Cheng Xu 
Supported by National Natural Science Foundation of China,No.82305376,No.82374577,No.82305375,No.82074532,and No.82405567;The Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD).
BACKGROUND Electroacupuncture(EA)has been recognized for its beneficial effects on glucolipid metabolism,potentially through the regulation of sensory nerve coordination.The expandability of peripancreatic adipose tis...
关键词:Insulin resistance ELECTROACUPUNCTURE Sensory nerve Transient receptor potential vanilloid 1 receptor Pancreatic beta cell Peripancreatic adipose tissue 
Hemoglobin glycation index among adults with type 1 diabetes:Association with double diabetes features
《World Journal of Diabetes》2025年第4期153-165,共13页Xiao-Lin Ji Min Yin Chao Deng Li Fan Yu-Ting Xie Fan-Su Huang Yan Chen Xia Li 
Supported by the National Key R D Program of China,No.2022YFC2010102;Natural Science Foundation of Hunan Province,No.2021JC0003;National Natural Science Foundation of China,No.82070812;the Sinocare Diabetes Foundation,No.LYF2022039.
ACKGROUND The hemoglobin glycation index(HGI)represents the discrepancy between the glucose management indicator(GMI)based on mean blood glucose levels and laboratory values of glycated hemoglobin(HbA1c).The HGI is a ...
关键词:Type 1 diabetes Double diabetes Insulin resistance Hemoglobin glycation index Advanced glycation end products Diabetic complications 
Role of metabolic dysfunction and inflammation along the liver-brain axis in animal models with obesity-induced neurodegeneration被引量:1
《Neural Regeneration Research》2025年第4期1069-1076,共8页Evridiki Asimakidou Eka Norfaishanty Saipuljumri Chih Hung Lo Jialiu Zeng 
supported by a Presidential Postdoctoral Fellowship (021229-00001) from Nanyang Technological University,Singapore (to JZ);a Lee Kong Chian School of Medicine Dean’s Postdoctoral Fellowship (021207-00001) from NTU Singapore;a Mistletoe Research Fellowship (022522-00001) from the Momental Foundaton,USA (to CHL)
The interaction between metabolic dysfunction and inflammation is central to the development of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease.Obesity-related conditions like type 2 d...
关键词:Alzheimer’s disease inflammatory cytokines insulin resistance LIPID 
Prognostic value of the triglyceride-glucose index in advanced gastric cancer:A call for further exploration
《World Journal of Gastroenterology》2025年第15期144-148,共5页Hong-Jie Meng Yi Mao De-Qing Zhao Sheng-Guang Shi 
Gastric cancer(GC)remains a leading cause of cancer-related mortality worldwide,necessitating the identification of reliable prognostic indicators to enhance treatment outcomes.Recent research has highlighted the trig...
关键词:Advanced gastric cancer CHEMOTHERAPY Insulin resistance Prognostic marker Triglyceride-glucose index Tumor microenvironment 
Cross-sectional study of the association between triglyceride glucose-body mass index and obstructive sleep apnea risk
《World Journal of Diabetes》2025年第3期65-75,共11页Li Gong Ming Su Jing-Han Xu Zhen-Fei Peng Lin Du Ze-Yao Chen Yu-Zhou Liu Lu-Cia Chan Yin-Luan Huang Yu-Tian Chen Feng-Yi Huang Chun-Li Piao 
Supported by Sanming Project of Medicine in Shenzhen,No.SZZYSM202202010。
BACKGROUND The triglyceride glucose-body mass index(TyG-BMI)is a novel indicator of insulin resistance(IR).Obstructive sleep apnea(OSA)is a prevalent disorder characterized by recurrent complete or partial collapse of...
关键词:Obstructive sleep apnea Triglyceride glucose-body mass index Insulin resistance CROSS-SECTIONAL National Health and Nutrition Examination Surveys 
Role of duodenal mucosal resurfacing in controlling diabetes in rats
《World Journal of Diabetes》2025年第3期243-259,共17页Li-Juan Nie Zhe Cheng Yi-Xian He Qian-Hua Yan Yao-Huan Sun Xin-Yi Yang Jie Tian Peng-Fei Zhu Jiang-Yi Yu Hui-Ping Zhou Xi-Qiao Zhou 
Supported by the National Natural Science Foundation of China,No.82474318;the Jiangsu Administration of Traditional Chinese Medicine,No.zt202105;Subject of Jiangsu Province Hospital of Chinese Medicine,No.Y2021rc22;a Research Career Scientist。
BACKGROUND The duodenum plays a significant role in metabolic regulation,and thickened mucous membranes are associated with insulin resistance.Duodenal mucosal resurfacing(DMR),a new-style endoscopic procedure using h...
关键词:Type 2 diabetes Duodenal mucosal resurfacing Gut microbiota Insulin resistance Blautia Gastric inhibitory peptide Glucagon-like peptide 1 
Electroacupuncture relieves type 2 diabetes by regulating gut microbiome
《World Journal of Diabetes》2025年第3期284-288,共5页Ya-Jing Yang Xu-Chang Zhou Hao-Ran Tian Feng-Xia Liang 
Cumulative studies have shown that the composition of the gut microbiome is strongly associated with the development of type 2 diabetes mellitus(T2DM).Electroacupuncture(EA)therapy has been reported to alleviate vario...
关键词:ELECTROACUPUNCTURE Type 2 diabetes mellitus Intestinal flora Intestinal microbiota Insulin resistance 
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