IRBESARTAN

作品数：62被引量：152H指数：7
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相关领域：医药卫生更多>>
相关作者：王国超何国祥孙静孙路路刘必成更多>>
相关机构：第三军医大学西南医院哈佛大学中国科学技术大学英国威尔士大学更多>>
相关期刊：《Journal of Hainan Medical University》《China Medical Abstracts(Internal Medicine)》《Current Medical Science》《Journal of Chinese Pharmaceutical Sciences》更多>>
相关基金：国家自然科学基金江苏省自然科学基金国家重点基础研究发展计划国家高技术研究发展计划更多>>
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Modeling solubility of oxaprozin and irbesartan in biorelevant complex solutions based on a combination of pH-dependent and micellar solubilization models
《Chinese Journal of Chemical Engineering》2024年第8期34-43,共10页Chen Shen Yuanhui Ji 
the financial support from the National Natural Science Foundation of China(22278070,21978047,21776046)。
Biological solubility is one of the important basic parameters in the development process of poorly soluble drugs,but the current measurement methods are mainly based on a large number of experiments,which are time-co...
关键词：Biorelevant media pH-dependent solubility Micellar solubilization PC-SAFT Active pharmaceutical ingredients 
PPARα activator irbesartan suppresses the proliferation of endometrial carcinoma cells via SREBP1 and ARID1A被引量：1
《Oncology Research》2023年第3期239-253,共15页YU LU TSUTOMU MIYAMOTO HODAKA TAKEUCHI FUMI TSUNODA NAOKI TANAKA TANRI SHIOZAWA 
supported by JSPS KAKENHI Grant Number 18K09285.
Endometrial carcinoma(EMC)is associated with obesity;however,the underlying mechanisms have not yet been elucidated.Peroxisome proliferator-activated receptor alpha(PPARα)is a nuclear receptor that is involved in lip...
关键词：Peroxisome proliferator-activated receptor alpha Sterol regulatory element-binding protein 1 ANTIOXIDANT Migration 
Effects of Jiawei Danggui Buxuetang on miRNA-155 and SOCS1 in renal tissue of DKD rats
《Journal of Hainan Medical University》2023年第1期21-27,共7页WANG Yi-fan GU Yue SHEN Yu-hang DING Xin LYU Zhe WANG Xin-ai GUO Deng-zhou 
supported by the Government Subsidizes the Training Program for Clinical Medical Talents(13000022P00DE341002470);Scientific Research Project of Hebei Administration of Traditional Chinese Medicine(2021167);Graduate Innovation Ability Training Program of Hebei University of Traditional Chinese Medicine(XCXZZBS2022018)。
Objective:To observe the effect of Jiawei Danggui Buxuetang on the expression of microRNA-155(miR-155)and cytokine signal transduction inhibitor 1(SOCS1)in renal tissue of rats with diabetic nephropathy(DKD),and to ex...
关键词：Jiawei Danggui Buxuetang Diabetic kidney disease IRBESARTAN MicroRNA-155 Cytokine signal transduction inhibitor 
Clinical Value Study on Irbesartan Hydrochlorothiazide Tablets in the Treatment of Patients with Essential Hypertension
《外文科技期刊数据库(文摘版)医药卫生》2022年第10期080-084,共5页WANGLei 
Objective: to investigate the effect of irbesartan hydrochlorothiazide tablets on patients with essential hypertension. Methods: 80 patients with primary hypertension admitted to the cardiology department of our hospi...
关键词：essential hypertension irbesartan hydrochlorothiazide tablets treatment effect safety blood rheo 
Expression of Nrf2/ARE pathway in diabetic nephropathy and renal protection of Qihuang Bushen Xiezhuo Formula
《Journal of Hainan Medical University》2022年第20期13-18,共6页JIN Li-xia ZHANG Xiao-dong PAN Chao LUAN Zhong-qiu SONG Shu-juan YIN Li-ying WANG Wen-kai 
General Project of Natural Science Foundation of Heilongjiang Province(No.H2016066);Young Chinese Medicine Science and Technology Innovation Project of Heilongjiang Chinese Medicine Association(No.ZHY19-023)。
Objective:To investigate the effect of Qihuang Bushen Xiezhuo Formula on the expression of the nuclear factor E2 related factor 2(Nrf2)/antioxidant response element(ARE)signaling pathway of human glomerular mesangial ...
关键词：Qihuang Bushen Xiezhuo Formula Oxidative stress High sugar Human glomerular mesangial cells IRBESARTAN 
Study on the Clinical Value of Irbesartan Hydrochlorothiazide Tablets in the Treatment of Patients with Essential Hypertension
《外文科技期刊数据库(文摘版)医药卫生》2022年第7期180-184,共5页LOULanchun WANGXuehong 
Objective: to compare the application value and safety benefit of irbesartan tablets and irbesartan hydrochlorothiazide compound preparation in the treatment of essential hypertension (EHT). Methods: according to the ...
关键词：essential hypertension irbesartan hydrochlorothiazide IRBESARTAN blood pressure control ADVERSE 
Evaluation of the Effect of Irbesartan Combined with PMA on Arrhythmia and Cardiac Function in Patients with Rheumatic Heart Disease
《Proceedings of Anticancer Research》2021年第2期49-52,共4页Jinping Li Zhongqi Xie 
Objective:To investigate the clinical effect of irbesartan combined with potassium magnesium aspartate(PMA)in the treatment of rheumatic heart disease.Methods:A total of 316 patients with rheumatic heart disease who w...
关键词：Rheumatic heart disease IRBESARTAN PMA ARRHYTHMIA Cardiac function 
Protective Effect of Irbesartan by Inhibiting ANGPTL2 Expression in Diabetic Kidney Disease被引量：3
《Current Medical Science》2020年第6期1114-1120,共7页Ling-na FANG Shao ZHONG Li-ji HUANG Bing LU Li-wen SHEN Feng-yan TANG He-ping SUN Li ZHANG 
This study was supported by Jiangsu University Medical Clinical Science and Technology Development(No.JLY201220045).
Angiopoietin-like protein 2(ANGPTL2)stimulates inflammation and is important in the pathogenesis of diabetic kidney disease(DKD).Irbesartan is helpful in reducing diabetes-induced renal damage.In this study,the effect...
关键词：angiopoietin-like protein 2(ANGPTL2) DIABETES KIDNEY inflammation 
Irbesartan desmotropes:Solid-state characterization,thermodynamic study and dissolution properties
《Journal of Pharmaceutical Analysis》2019年第5期339-346,共8页Andrea Mariela Araya-Sibaja Carlos Eduardo Maduro de Campos Cinira Fandaruff Jose Roberto Vega-Baudrit Teodolito Guillen-Giron Mirtha Navarro-Hoyos Silvia Lucía Cuffini 
financial support of FEES-CONARE (Ref 115B5662);the University of Costa Rica (UCR);the Costa Rica Institute of Technology (TEC);the National Laboratory of Nanotechnology (LANOTEC)
Irbesartan (IBS) is a tetrazole derivative and antihypertensive drug that has two interconvertible structures, 1H- and 2H-tautomers. The difference between them lies in the protonation of the tetrazole ring. In the so...
关键词：IRBESARTAN SOLID-STATE CHARACTERIZATION INTRINSIC DISSOLUTION rate TAUTOMERISM Desmotropic forms 
Effects of Bailing capsule combined with irbesartan on oxidative stress, inflammatory response and immune function in patients with diabetic nephropathy
《Journal of Hainan Medical University》2019年第9期33-36,共4页Zhong Li Guang-Ming Zhang Sha Zheng Jia-JiaZheng  Yan Zhang Ping Yuan 
Objective: To explore the effects of Bailing capsule combined with irbesartan on oxidative stress, inflammatory response and immune function in patients with diabetic nephropathy. Methods: 142 patients with diabetic n...
关键词：BAILING CAPSULE IRBESARTAN DIABETIC NEPHROPATHY Oxidative stress Inflammatory response Immune function 
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