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作品数:350被引量:574H指数:12
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Polymorphism analysis of virulence-related genes among Candida tropicalis isolates被引量:1
《Chinese Medical Journal》2019年第4期446-453,共8页Li-Juan Zhang Shuan-Bao Yu Wen-Ge Li Wen-Zhu Zhang Yuan WU Jin-Xing Lu 
the National Natural Science Foundation of China (Youth Project No.81301409);the National Sci-Tech Key Project (No.2013ZX10004203-002).
Background: Adhesion, biofilm formation, yeast-hyphal transition, secretion of enzymes, and hemolytic activity are all considered important factors in Candida tropicalis infection. However, DNA sequence data for this ...
关键词:CANDIDA TROPICALIS Virulence-related GENES PHYLOGENETIC analysis GENE ALS GENE LIP GENE SAP 
White-opaque Switching in Different Mating Type-like Locus Gene Types of Clinical Candida albicans Isolates
《Chinese Medical Journal》2016年第22期2725-2732,共8页Hou-Min Li Yumi Shimizu-Imanishi Reiko Tanaka Ruo-Yu Li Takashi Yaguchi 
Background:Candida albicans (C.albicans) can become a pathogen causing superficial as well as life-threatening systemic infections,especially in immunocompromised patients.Many phenotypic attributes contribute to i...
关键词:Candida albicans Drug Susceptibility GENOTYPE Mating Type-like White-opaque 
Species Distribution and In Vitro Antifungal Susceptibility of Vulvovaginal Candida Isolates in China被引量:16
《Chinese Medical Journal》2016年第10期1161-1165,共5页Feng-Juan Wang Dai Zhang Zhao-Hui Liu Wen-Xiang Wu Hui-Hui Bai Han-Yu Dong 
Acknowledgements The authors are thankful to all the clinicians and microbiologists for referring vulvovaginal yeast isolates to the mycology reference laboratory. Excellent technical support received from Min Zhao is acknowledged.Financial support and sponsorship This study was supported by a grant from the National Natural Science Foundation of China (No. 81571394).
Background: Vulvovaginal candidiasis (WC) was a common infection associated with lifelong harassment of woman's social and sexual life. The purpose of this study was to describe the species distribution and in vit...
关键词:Drug Resistance Infection Diseases Susceptibility Surveillance Vulvovaginal Candidiasis: Women's Health 
Multilocus sequence typing indicates diverse origins of invasive Candida tropicalis isolates in China被引量:1
《Chinese Medical Journal》2014年第24期4226-4234,共9页Fan Xin Xiao Meng Wang He Zhang Li Kong Fanrong Lu Juan Hu Zhidong Kang Mei Xu Yingchun 
Background According to data from the China Hospital Invasive Fungal Surveillance Net (CHIF-NET) 2010, Candida tropica/is (C. tropica/is) is the third most common pathogen causing invasive candidiasis. Moreover, t...
关键词:Candida tropicalis invasive fungal infections multilocus sequence typing phylogenetic analysis 
Genetic environment of β-lactamase genes of extended-spectrum β-lactamase-producing Klebsiella pneumoniae isolates from patients with lower respiratory tract infection in China被引量:5
《Chinese Medical Journal》2014年第13期2445-2450,共6页Liu Lin Wang Xiaorong An Shuchang Zhang Xiangyan Chen Lin Li Yuqian Xu Li Zhang Yijie Gao Zhancheng 
Background Extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae (K.pneumoniae) is one of the most popular pathogens that cause refractory respiratory tract infection.The genetic environment,includ...
关键词:Klebsiella pneumoniae PROMOTER Β-LACTAMASE insertion sequence 
Characterization of erythromycin-resistant Streptococcus pneumoniae isolates causing invasive diseases in Chinese children被引量:2
《Chinese Medical Journal》2013年第8期1522-1527,共6页MA Xiang YAO Kai-hu XIE Gui-lin ZHENG YUE-jie WANG Chuan-qing SHANG Yun-xiao WANG Hui-yun WAN Li-Ya LIU Lan LI Chang-chong JI Wei XU Xi-wei WANG Ya-ting XU Pei-ru YU Sang-jie YANG Yong-hong 
Background Erythromycin-resistant Streptococcus pneumoniae isolates that causing invasive pneumococcal diseases (IPD) in Chinese children remain uncharacterized. This study aims to identify the resistance genes asso...
关键词:Streptococcus pneumonia invasive pneumococcal diseases  erythromycin resistance  genes 
Immunogenicities of Env glycoproteins from circulating HIV-1 isolates in China focusing on the strategy of "DNA prime plus protein boost"被引量:3
《Chinese Medical Journal》2009年第19期2339-2345,共7页WANG Zheng WANG Shi-xia LIU Si-yang BAO Zuo-yi ZHUANG Dao-min LI Lin ZHANG Chun-hua ZHANG Lu LI Jing-yun LU Shan 
This work was supported by the grants from the China 973 Project (No. 2006CB504206) and the Natural Science Foundation of China (No. 30700706). In addition, this work was supported by a funding from Jiangsu Provincial Key Infectious Diseases Laboratory.
Background The adenovirus-based HIV-1 vaccine developed by Merck Company suffered from an unexpected failure in September 2007. This generated a big shift in the strategy of HIV vaccine development with renewed focus ...
关键词:human immunodeficiency virus type 1 DNA vaccine DNA prime protein boost neutralizing antibody 
Characterization of multidrug-resistant and metallo-beta- lactamase-producing Pseudomonas aeruginosa isolates from a paediatric clinic in China被引量:8
《Chinese Medical Journal》2008年第17期1611-1616,共6页DONG Fang XU Xi-wei SONG Wen-qi LU Ping YU Sang-jie YANG Yong-hong SHEN Xu-zhuang 
Background In the present study, we characterized multidrug-resistant Pseudomonas aeruginosa (MDRP) clinical isolates from a paediatric facility and investigated the types and features of the metallo-β-lactamases ...
关键词:PAEDIATRICS Pseudomonas aeruginosa carbapenem  metallo-β-lactamases 
DNA sequence analysis of the triose phosphate isomerase gene from isolates of Giardia lamblia被引量:1
《Chinese Medical Journal》2002年第1期99-102,151-152,共4页卢思奇 文建凡 李继红 王凤云 
Objective To confirm the genetic relation between Giardia lamblia (G. lamblia) isolates from different geographic regions of China and other countries.Methods Genomic DNA were extracted from the trophozoites or cyst...
关键词:Giardia lamblia   ·  triose phosphate isomerase   · tim gene   ·  gene sequence analysis   ·   genotype 
Comparison between homologies of E2/NS1 gene from genotype Ⅲ Chinese isolates of hepatitis C virus and that from reported isolates被引量:2
《Chinese Medical Journal》1998年第9期39-41,共3页吴朝栋 陶其敏 
HepatitisCvirus(HCV)isthemajorcausativeagentofnonA,nonBhepatitisthroughouttheworld.1Recently,itwassuggestedt...
关键词:GENE GENOTYPE E2/NS1 COMPARISON CHINESE 
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