Β-LACTAMASE

作品数：56被引量：88H指数：6
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相关领域：医药卫生更多>>
相关作者：周伟琳丁永祥马亦林陈亚岗俞云松更多>>
相关机构：浙江大学医学院附属第一医院中国医学科学院北京协和医学院郑州牧业工程高等专科学校首都医科大学更多>>
相关期刊：《World Journal of Biological Chemistry》《Engineering》《Acta Biochimica et Biophysica Sinica》《Frontiers of Medicine》更多>>
相关基金：国家自然科学基金广东省自然科学基金国家重点基础研究发展计划更多>>
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A β-lactamase-activatable photosensitizer for the treatment of resistant bacterial infections
《Chinese Chemical Letters》2024年第11期402-405,共4页Zhipeng Li Qincong Feng Jianliang Shen 
financially supported by the National Natural Science Foundation of China (No.21977081);Zhejiang Provincial Natural Science of Foundation of China (No.LQ21H190006)。
Antibacterial agent of activatable photosensitizer not only has the advantages of traditional photosensitizers,such as good curative effect and low resistance,but also has better selectivity for bacteria and lower tox...
关键词：Activatable photosensitizer MRSA Β-LACTAMASE Fluorescence imaging aPDT 
Identification of a novel multi-drug resistant plasmid co-harbouring extended-spectrumβ-lactamase resistance genes bla_(PER-4)and bla_(OXA-10)in Moellerella wisconsensis of sheep
《Journal of Integrative Agriculture》2024年第9期3238-3242,共5页Xueliang Zhao Yongqiang Miao Hongmei Chen Honghu Shan Juan Wang Yang Wang Jianzhong Shen Zengqi Yang 
funded by the National Natural Science Foundation of China(32141002);the Postdoctoral Fellowship Program of CPSF under Grant,China(GZC20241939);the China Agriculture Research System of MOF and MARA(CARS-39-14).
Moellerella wisconsensis is proposed for a member of the family Enterobacteriaceae previously designated as Enteric Group 46.In 1984,the majority of the bacterial isolates(6/8,75%)had been identified in Wisconsin,USA(...
关键词：Brenner PASSAGE 
The Triple Combination of Meropenem,Avibactam,and a Metallo-β-Lactamase Inhibitor Optimizes Antibacterial Coverage Against Different β-Lactamase Producers
《Engineering》2024年第7期124-132,共9页Zhuoren Ling Alistair James Macdonald Farley Aditya Lankapalli Yanfang Zhang Shonnette Premchand-Branker Kate Cook Andrei Baran Charlotte Gray-Hammerton Claudia Orbegozo Rubio Edgars Suna Jordan Mathias Jürgen Brem Kirsty Sands Maria Nieto-Rosado Maria Mykolaivna Trush Nadira Naznin Rakhi Willames Martins Yuqing Zhou Christopher Joseph Schofield Timothy Walsh 
supported by the Ineos Oxford Institute for Antimicrobial Research,the Biotechnology and Biological Sciences Research Council(BB/V003291/1);the WellcomeTrust(106244/Z/14/Z).
This work explores the potential of a triple combination of meropenem(MEM),a novel metallo-blactamase(MBL)inhibitor(indole-2-carboxylate 58(InC58)),and a serine-b-lactamase(SBL)inhibitor(avibactam(AVI))for broad-spect...
关键词：CARBAPENEMASE Metallo/serine-b-lactamase inhibitor Avibactam MEROPENEM Antimicrobial resistance 
Trends in antimicrobial resistance in Enterobacterales isolated from children: data from the China Antimicrobial Surveillance Network (CHINET) from 2015-2021
《One Health Advances》2024年第1期122-130,共9页Fen Pan Chun Wang Yang Yang Yan Guo Demei Zhu Hong Zhang China Antimicrobial Surveillance Network(CHINET)Study Group 
supported by the China Antimicrobial Surveillance Network(Independent Medical Grants from Pfizer,2020QD049);the China Antimicrobial Surveillance Network(Independent Medical Grants from Pfizer,2018QD100);Shanghai Antimicrobial Surveillance Network(3030231003);development of high sensitivity multipathogen-specific antibody detection kit(grant numbers 21S31901900);Shanghai"Rising Stars of Medical Talents"Youth Development Program(Youth Medical Talents-Clinical Laboratory Practitioner Program).
Antimicrobial resistance poses a significant threat to global public health,especially for Enterobacterales.In this study,we investigated the distribution and antimicrobial resistance of Enterobacterales in children i...
关键词：CHILDREN Enterobacterales Bacterial resistance surveillance Extended-spectrumβ-lactamase Carbapenem-resistant Enterobacterales 
Characteristics of β-Lactamase Synthesis in E. coli and K. pneumanie Strains in Nosocomial Infections
《Advances in Microbiology》2024年第1期25-30,共6页Saddraddin A. Atakishizadeh Sayyaddin A. Atakishizadeh Mahammad M. Davudov 
Background: Recently micro-organisms that synthesize extended-spectrum β-lactamase (ESBLs) were increased. The peculiarities of ESBL synthesis of Escherichia coli and Klebsiella pneumoniae strains that cause nosocomi...
关键词：Nosocomial Infectious Agents β-Lactamase Synthesis E. coli and K. pneumoniae 
Prevalence and Risk Factors of Penicillinase-Type β-Lactamase Producing Neisseria gonorrhoeae Isolated from Patients Attending Health-Facilities in Yaounde, Cameroon
《Open Journal of Medical Microbiology》2023年第3期220-233,共14页Cécile Ingrid Djuikoue Laurene Nzangem Doumene Cedric Seugnou Nana Joviale Magne Talla Herman Koyouo Tagne Blondelle Kitio Messeu Farid Wega Tobie Vianney Kamany Kamdem Willy Yamdeu Djonkouh Ghandhi Fossouo Ndieffouo Carole Tayimetha Benjamin D. Thumamo Pokam Nicolas Antoine-Moussiaux 
Background and Objectives: Mitigation of antibiotic resistant Neisseria gonorrhoeae has become a priority due to considerable health and economical disabilities it generates. In order to tackle the emergence of resist...
关键词：Neisseria gonorrhoeae Antimicrobial Resistance Β-LACTAMASE PENICILLINASE Cameroon 
Selective inhibition of resistant bacterial pathogens using a β-lactamase-activatable antimicrobial peptide with significantly reduced cytotoxicity
《Chinese Chemical Letters》2023年第5期241-245,共5页Weipan Xu Zheng Ma Geetika Dhanda Jayanta Haldar Hexin Xie 
financial support from the NSFC-BRICS(No.81861148020,H.Xie);the Fundamental Research Funds for the Central Universities(H.Xie);the Research Program of State Key Laboratory of Bioreactor Engineering(H.Xie);DST-BRICS multilateral cooperation project(DST/IMRCD/BRICS/PilotCall2/MBLI/2018(G))。
The expression ofβ-lactamase,particularly metallo-β-lactamase(MBL)in bacteria has caused significant resistance to clinically importantβ-lactam antibiotics,including life-saving carbapenems.Antimicrobial peptides(A...
关键词：Antibiotic resistance Β-LACTAMASE Antimicrobial peptide CYTOTOXICITY 
Phenotypic and Genotypic Characterisation of Antibiotic Resistance in Escherichia coli, Klebsiella spp., and Listeria monocytogenes Isolates from Raw Meat Sold in Nairobi
《Advances in Microbiology》2022年第11期603-620,共18页Anita Chepkemei John Mwaniki Andrew Nyerere John Kiiru 
Worldwide, the increase in antimicrobial resistance (AMR) is a public health concern. Food-borne associated antibiotic-resistant pathogens can contaminate raw meat during slaughter, transportation, and at sale points....
关键词：Raw Meat Escherichia coli Listeria monocytogenes Multidrug Resistance Extended Spectrum β-Lactamase (ESBL) 
Unravelling Antimicrobial Resistance Phenotypes and Carriage of Extended-Spectrum β-Lactamase Genes in Escherichia coli Isolated from Dairy Farms in Kiambu County, Kenya
《Advances in Microbiology》2022年第5期295-315,共21页Dan Waithiru John Mwaniki Njeru John M. Maingi Erastus Mulinge Benjamin Ngugi John Maina John Kiiru 
The use of antibiotics for prophylaxis and growth enhancement in livestock farming is on the increase globally. This practice has led to the emergence and spread of antimicrobial-resistant bacteria in livestock. Only ...
关键词：Humans Cattle Slurry Escherichia coli Multidrug Resistance Extended-Spectrum β-Lactamase (ESBL) TEM 116 CTX-M-15 Kenya 
Prevalence,serotyping and drug susceptibility patterns of Escherichia coli isolates from kidney transplanted patients with urinary tract infections
《World Journal of Biological Chemistry》2020年第3期112-118,共7页Atefeh Najafi Khah Mojdeh Hakemi-Vala Shiva Samavat Mohammad Javad Nasiri 
Supported by Research Department of School of Medicine Shahid Beheshti University of Medical Sciences,No.17920,and accepted by the ethic committee,Code.IR.SBMU.MSP.REC.1398.349.
BACKGROUND Extended-spectrumβ-lactamase(ESBL)-producing Escherichia coli(E.coli)are among the main pathogens in urinary tract infections(UTIs)among kidney transplant patients(KTPs).AIM To estimate the prevalence of E...
关键词：Kidney transplantation Urinary tract infection Drug resistance Escherichia coli SEROTYPING Β-LACTAMASE 
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