MEROPENEM

作品数：32被引量：82H指数：6
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相关领域：医药卫生更多>>
相关作者：李家泰张永龙田晓峰顾俊明霍丽更多>>
相关机构：北京医科大学第一医院北京大学第一医院湖北医科大学附属第一医院大连医科大学更多>>
相关期刊：《中国临床药理学杂志》《中国药物化学杂志》《Journal of Hainan Medical University》《Current Medical Science》更多>>
相关基金：国家自然科学基金更多>>
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Evaluation Criteria and Rationality Analysis of Drug Utilization of Meropenem in a Tertiary Medical Institution in Beijing
《Asian Journal of Social Pharmacy》2025年第1期1-9,共9页Zhang Qiming Huang Zhe 
Objective To establish a drug use evaluation(DUE)standard for meropenem in a tertiary medical institution in Beijing,and to analyze the use of meropenem for promoting the rational use of antibiotics.Methods A criteria...
关键词：MEROPENEM ANTIBIOTICS rational use drug use evaluation 
The Triple Combination of Meropenem,Avibactam,and a Metallo-β-Lactamase Inhibitor Optimizes Antibacterial Coverage Against Different β-Lactamase Producers
《Engineering》2024年第7期124-132,共9页Zhuoren Ling Alistair James Macdonald Farley Aditya Lankapalli Yanfang Zhang Shonnette Premchand-Branker Kate Cook Andrei Baran Charlotte Gray-Hammerton Claudia Orbegozo Rubio Edgars Suna Jordan Mathias Jürgen Brem Kirsty Sands Maria Nieto-Rosado Maria Mykolaivna Trush Nadira Naznin Rakhi Willames Martins Yuqing Zhou Christopher Joseph Schofield Timothy Walsh 
supported by the Ineos Oxford Institute for Antimicrobial Research,the Biotechnology and Biological Sciences Research Council(BB/V003291/1);the WellcomeTrust(106244/Z/14/Z).
This work explores the potential of a triple combination of meropenem(MEM),a novel metallo-blactamase(MBL)inhibitor(indole-2-carboxylate 58(InC58)),and a serine-b-lactamase(SBL)inhibitor(avibactam(AVI))for broad-spect...
关键词：CARBAPENEMASE Metallo/serine-b-lactamase inhibitor Avibactam MEROPENEM Antimicrobial resistance 
Quantification of Structurally Alert Mutagenic Impurities in Meropenem Trihydrate Drug Substance by Liquid Chromatography with High Resolution Mass Spectrometer (LC-HRMS)
《American Journal of Analytical Chemistry》2024年第3期119-133,共15页Anwar Sulaiman K. Ramakrishna Reddy Vundavilli Jagadeesh Kumar Hemant Kumar Sharma 
Potential mutagenic impurities in Active Pharmaceutical Ingredient, Meropenem Trihydrate were assessed and a novel analytical method for their quantification was developed and validated. This Liquid Chromatographic me...
关键词：Mutagenic Impurities LC-HRMS Meropenem Trihydrate Method Validation 
Treatment of Donor-derived Carbapenem-resistant Klebsiella pneumoniae Infection after Renal Transplantation with Tigecycline and Extended-infusion Meropenem被引量：8
《Current Medical Science》2021年第4期770-776,共7页Zhi-qiang WANG Zhi-liang GUO Hao FENG Cheng FU Guang-yuan ZHAO Ke MA Lan ZHU Gang CHEN 
supported by grants from Non-Profit Central Research Institute Fund of Chinese Academy of Medical Science(No.2018PT32018);Hubei Science and Technology Plan(No.2017ACA096).
Objective Donor-derived carbapenem-resistant Klebsiella pneumoniae(CRKP)infection has recently emerged as a critical early complication after renal transplantation.Although CRKP is usually sensitive to tigecycline,mon...
关键词：renal transplantation donor-derived infection carbapenem-resistant Klebsiella pneumoniae TIGECYCLINE MEROPENEM 
Detection of Gram-Negative Bacteria Carrying the blaKPC-2 Gene from Mangrove Sediments
《Journal of Pharmacy and Pharmacology》2019年第8期485-492,共8页Wallace Ribeiro Nunes Neto Jessica Mayara Mendes Araujo Darlan Ferreira da Silva Joveliane de Melo Monteiro Wallace Borges Pachêco Jessflan Rafael Nascimento Santos Maria Raimunda Chagas Silva Maria Rosa Quaresma Bomfim Andrea de Souza Monteiro 
Mangroves are environments that have fast cycles associated with high concentration of bacterial decomposers.These are impacted by anthropogenic pollution due to contamination of bacterial species carrying resistance ...
关键词：Antibiotic RESISTANT MEROPENEM BACTERIAL ISOLATES 
Commentary on the “Measurement and correlation of solubility of meropenem trihydrate in binary(water ＋ acetone/tetrahydrofuran)solvent mixtures”
《Chinese Journal of Chemical Engineering》2018年第10期2127-2129,共3页Renjie Xu Min Zheng Jiao Chen Hongkun Zhao 
Supported by the Natural Science Foundation of Guangling College,Yangzhou University(ZKYB17007);the Innovation and Entrepreneurship Training Project for Undergraduate of Jiangsu Higher Education Institutions(201813987006Y)
Problem was discussed on the reported equation parameters by Zhou and co-workers [Chinese Journal of Chemical Engineering 25(10)(2017) 1461–1466] for expressing the meropenem trihydrate solubility in binary(water + a...
关键词：二进制代码 溶解度 混合物 水 评论 溶剂 关联 测量 
Meropenem/Vaborbactam(Vabomere)
《中国药物化学杂志》2018年第2期171-171,共1页梁昕杰 董金华 
2017年8月29日，美国FDA批准Rempex Pharms Medcns公司的新型抗菌药美罗培南一法硼巴坦在美国上市，商品名为Vabomere。该药适用于治疗18岁及以上患者的复杂尿路感染（CUTI），包括由特定细菌如大肠杆菌、肺炎克雷伯杆菌、阴沟肠杆菌等...
关键词：抗菌药 药物分析 药物治疗 治疗方法 
Measurement and correlation of solubility of meropenem trihydrate in binary(water＋acetone/tetrahydrofuran) solvent mixtures被引量：4
《Chinese Journal of Chemical Engineering》2017年第10期1461-1466,共6页Lina Zhou Shichao Du Ting Wang Songgu Wu Zhiqiang Guo Zhao Wang Ling Zhou 
Supported by Tianjin Municipal Natural Science Foundation(16JCYBJC19500);China Ministry of Science and Major National Scientific Instrument Development Project(2016YFF0102503)
The solubility of meropenem trihydrate in water+acetone mixtures and water+tetrahydrofuran mixtures were determined from T=(278.15 to 303.15) K by static method under atmospheric pressure.Effects of solvent compositio...
关键词：Solubility Meropenem trihydrate Thermodynamics 
Effect of dobutamine combined with meropenem on serum BNP, IGF-1, IGFBP-3, TNF-a, IL-6 and hs-CRP in children with congenital heart disease and pneumonia被引量：1
《Journal of Hainan Medical University》2017年第12期83-86,共4页Yan-Li Xie Tao Wang 
Objective:To study the effect of dobutamine combined with meropenem on serum BNP, IGF-1, IGFBP-3, TNF-a, IL-6 and hs-CRP in children with congenital heart disease and pneumonia.Methods:A total of 70 children with cong...
关键词：DOBUTAMINE MEROPENEM Congenital heart disease PNEUMONIA Children BNP IGF-1 IGFBP-3 Inflammatory factor 
Pharmacokinetic and Pharmacodynamic Efficacies of Continuous versus Intermittent Administration of Meropenem in Patients with Severe Sepsis and Septic Shock： A Prospective Randomized Pilot Study被引量：8
《Chinese Medical Journal》2017年第10期1139-1145,共7页Hui-Ying Zhao Jian Gu Jie Lyu Dan Liu Yi-Tong Wang Fang Liu Feng-Xue Zhu You-Zhong An 
Background： The antibiotic meropenem is commonly administered pharmacokinetic, clinical, and bacteriological efficacies of continuous patients. n patients with severe sepsis and septic shock. We compared the infusion...
关键词：Continuous Infusion Intermittent Infusion MEROPENEM Pharrnacodynanlic PHARMACOKINETIC 
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