supported by grants received from CAAST-ACLH(NAHEP/CAAST/2018-19);ICAR-World Bank-funded National Agricultural Higher Education Project(NAHEP).
Background:Vancomycin resistance(VR)in staphylococci is emerging fast and posing serious health problems as vancomycin is considered the drug of choice for the treatment of methicillin-resistant staphylococcal infecti...
supported by the National Key Research and De-velopment Program of China[grant number 2022YFE0199800];Key R&D Program of Shandong Province[grant number 2020CXGC011305];Shandong Provincial Natural Science Foundation[grant number ZR2020MH308];the National Natural Science Foundation of China[grant number 82,271,658].
Tigecycline serves as a critical“final-resort”antibiotic for treating bacterial infections caused by multidrug-resistant bacteria for which treatment options are severely limited.The increasing prevalence of tigecyc...
Objective:To study the clinical efficacy and safety of tigecycline in the treatment of acute exacerbation of chronic obstructive pulmonary disease(COPD)combined with multidrug-resistant Acinetobacter baumannii infecti...
supported by the National Key Research and Development Program of China(No.2022YFD1800400);National Natural Science Foundation of China(No.81991531);Natural Science Foundation of Shandong Province(No.ZR2020MC188);The sequence data of 25 K.pneumoniae isolates have been submitted to NCBI under BioProject accession number PRJNA1011004.
The rapid spread of mobile tigecycline resistance presents a significant public health threat,particularly with the increasing prevalence of tet(X4)-positive Enterobacterales across various species.This study aimed to...
supported by Natural Science Foundation of Chongqing,China(cstc2021jcyj-msxmx0027);Talent and Innovation Project of Beibei District in Chongqing(2022-11);Performance Incentive and Guidance Special Project of Scientific Research Organization,Chongqing Science and Technology(cstc2021jxjl130024).
Long-wavelength fluorescence carbon dots (CDs) show great importance in multiple fields,especially for the biochemical sensing.Here,we proposed one type of CDs doped with nitrogen and sulfur through the hydrothermal m...
supported by the National Key Research and Development Program of China(2021YFD1801000);National Natural Science Foundation of China(32222084,32002331 and 32172907);Jiangsu Agricultural Science and Technology Innovation Fund(CX(21)2010);A Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)and 111 Project D18007。
The emergence and prevalence of plasmid-encoded RND-type efflux pump TMexCD-TOprJ severely compromise tigecycline treatment,which is recognized as the last resort for multidrug-resistant(MDR)Gram-negative bacterial in...
We thank Yang Liu for graphics support.This study was supported by CAS(XDB29050400,KFJ‐STS‐QYZX‐087);NSFC(31827801,82072318);National Key Research and Development Program of China(2018YFE0101800,2021YFC2301002);Traditional Chinese Medicine Science and Technology Development Program of Shandong Province(No.2019‐0596).
Antimicrobial susceptibility tests(ASTs)are pivotal in combating multidrug resistant pathogens,yet they can be time‐consuming,labor‐intensive,and unstable.Using the AST of tigecycline for sepsis as the main model,he...
BACKGROUND Metal-on-metal(MoM)total hip arthroplasty(THA)has been associated with adverse reactions to metal debris,presenting clinically as pseudotumors.CASE SUMMARY This case report presents a female aged 73 year-ol...
This study was supported by the Major Program of National Natural Science Foundation of China(81991534);the Major State Basic Research Development Program(2018YFC1603803);the National Key Research and Development Program of China(grant number:2018YFC1603900).
The emergence and spread of plasmid-mediated tigecycline resistance genes have attracted extensive attention worldwide.We investigated the distribution of mobile tigecycline resistance genes in Salmonella genomes gene...
supported by grants from Non-Profit Central Research Institute Fund of Chinese Academy of Medical Science(No.2018PT32018);Hubei Science and Technology Plan(No.2017ACA096).
Objective Donor-derived carbapenem-resistant Klebsiella pneumoniae(CRKP)infection has recently emerged as a critical early complication after renal transplantation.Although CRKP is usually sensitive to tigecycline,mon...