supported by grants received from CAAST-ACLH(NAHEP/CAAST/2018-19);ICAR-World Bank-funded National Agricultural Higher Education Project(NAHEP).
Background:Vancomycin resistance(VR)in staphylococci is emerging fast and posing serious health problems as vancomycin is considered the drug of choice for the treatment of methicillin-resistant staphylococcal infecti...
Objective To evaluate the antibacterial efficacy of ceftobiprole,vancomycin,linezolid,and daptomycin against Staphylococcus aureus(SAU)and coagulasenegative Staphylococcus(CNS)bloodstream infections,which can provide ...
Supported by the Scientific and Technological Project of Shiyan City of Hubei Province,No.21Y32;the Medical Research Project of Hubei Pediatric Alliance,No.HPAMRP202114.
BACKGROUND Although neonatal Staphylococcus aureus pneumonia is common and usually curable,it can also be refractory and life-threatening.Herein,we report a case of severe neonatal community-acquired methicillin-resis...
Background:Linezolid-associated thrombocytopenia(LAT)leads to drug withdrawal associated with a poor prognosis.Some risk factors for LAT have been identified;however,the sample size of previous studies was small,data ...
The relevant works were supported by grants from the horizontal project of West China Hospital of Sichuan University(Grant No.321190602).
Background:To characterize the population of critically ill patients and infections treated with linezolid in the intensive care unit(ICU),and to evaluate the clinical efficacy and safety of linezolid therapy.Methods:...
National Natural Science Foundation of China(Nos.81874265,82073561);Shanghai Jiao Tong University School of Medicine(No.2020002);Shanghai Science and Technology Commission(Nos.18411966600,19410740800);Key Discipline Construction Plan from Shanghai Municipal Health Commission(No.GWV-10.1-XK01);National Ministry of Science and Technology-National Key R&D Program Project(No.2021YFE0201900);and National Respiratory Field Key Laboratory Emergency Project(No.EKPG21-08).
Background We aimed to evaluate the tolerability and efficacy of linezolid in children for treating suspected and diagnosed Gram-positive bacterial infections.Methods A systematic literature search was conducted up to...
Objective:To assess the effectiveness and adverse drug reactions of all-oral regimens for patients with multidrug-resistant tuberculosis.Methods:This retrospective study was conducted at 10 Programmatic Management of ...
Oxazolidinones are groups of synthetic antimicrobial agents, which have a novel chemical structure. Their mechanism of antimicrobial mainly bacteriostatic via inhibition of protein synthesis. Oxazolidinones are used i...
Background:Shunt systems are used to provide cerebrospinal fluid drainage in the treatment of hydrocephalus.Recently,antibiotic-impregnated shunt systems are used to prevent colonization in the ventriculoperitoneal ca...
Supported by the Project of Nanfang Hospital President Foundation of Southern Medical University,No.2019C006。
BACKGROUND Nocardia paucivorans is an infrequently found bacterium with the potential to cause severe infection,with a predilection for the central nervous system,both in immunocompromised and immunocompetent individu...