supported by the National Natural Science Foundation of China(Nos.81860543,32360237);Guizhou Provincial Science and Technology Projects(Nos.ZK[2024]235,ZK[2023]Key Project 041).
The escalation in the incidence of multidrug-resistant Gram-negative bacteria is becoming a pressing global concern.Polymyxin B(PMB),a conventional antibiotic with notable therapeutic efficacy against Gram-negative ba...
This manuscript is based on a recent study by Pillay et al that was published in recently.Liver abscesses can be caused by rare potentially life-threatening infections of either bacterial or parasitic origin.The incid...
Supported by the Key Research and Development Project of the Science and Technology Department of Sichuan Province,China,No.2023YFS0280;the High-level Research Initiation Fund Program of the First Affiliated Hospital of Chengdu Medical College,China,No.CYFY-GQ43.
This article discusses the findings presented by Zhang et al.They analyzed the risk factors and clinical characteristics associated with Klebsiella pneumoniae infection in patients with liver cirrhosis treated at a ho...
BACKGROUND Liver transplant(LT)recipients are susceptible to carbapenem-resistant Klebsiella pneumoniae(CRKP)infections.Comprehensive research addressing the incidence,timing,infection sites,resistance patterns,treatm...
Introduction: The misuse of antibiotics has driven the emergence of antimicrobial resistance, with certain bacterial species, including Klebsiella pneumoniae, initially susceptible to most antibiotics, now exhibiting ...
funded by theNational KeyR&DProgram of China(2023YFD1800800);the Basic Scientific Research Business Expenses of Central Public Welfare Scientific Research Institutes,China(Y2022YJ14);the Technology Innovation Project of Hubei Province,China(2022BEC033);the Innovation Program of Chinese Academy of Agricultural Sciences-Veterinary Natural Medicine and Antibiotic Replacement,China(25-LZIHPS-03).
Colistin serves as a crucial treatment for multidrugresistant(MDR)Gram-negative bacterial infections.However,its excessive use has contributed to an increase in colistin-resistant strains within livestock production(B...
The increase and spread of bacterial resistance to extended-spectrum beta-lactam antibiotics are reported in many infections and are a real public health problem worldwide. Drug pressure is a factor that favors the em...
Urinary tract infections (UTIs) caused by uropathogens are a significant public health problem, and their treatment primarily relies on antibiotic therapy. However, the increasing global development of antibiotic resi...
Supported by the National Key R&D Program of China,No.2021YFC2301800.
BACKGROUND The incidence of Klebsiella pneumoniae(K.pneumoniae)infection in patients with cirrhosis has been increasing over recent years,posing certain difficulties in clinical treatment.AIM To analyze the clinical f...
supported by the National Key Research and Development Program of China(2021YFC2300300);Key Research and Development Program of Zhejiang Province(2021C03068);National Natural Science Foundation of China(81971984 and 82202588);Shandong Provincial Laboratory Project(SYS202202).
The emergence of hypervirulence(hv)and carbapenem resistance(CR)as distinct evolutionary directions for Klebsiella pneumoniae presents a significant threat in clinical settings.However,in recent years,there has been a...