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Engineering high-performance chemiluminescent probes via enzymatic pocket targeting:high-throughput screening for ultralong afterglow imaging of orthotopic hepatocellular carcinoma
《Science China Chemistry》2025年第3期1175-1184,共10页Shuai Huang Shuaige Bai Ting Luo Bin Feng Min Liu Fan Zheng Shuang Huang Yanpeng Fang Dan Ding Wenbin Zeng 
supported by the National Natural Science Foundation of China (82272067,22107123,and M-0696);the Natural Science Foundation of Hunan Province (2022JJ80052)。
Hepatocellular carcinoma(HCC)is a highly aggressive liver malignancy and the main form of liver cancer.Early diagnosis and treatment of HCC can effectively reduce mortality.Carboxylesterase(CE)-specific detection and ...
关键词：chemiluminescent probes CARBOXYLESTERASE high-throughput inhibitor screening long-lived chemiluminescent image image-guided surgery 
The Qixiangzhan Lava Flow at the Tianchi Volcano:Eruptive Dynamics,Emplacement Mechanism and Implications for the Formation of Long-lived Magmatic Systems Prior to Caldera-forming Eruptions
《Acta Geologica Sinica(English Edition)》2025年第1期114-125,共12页LI Jiahui SHAN Xuanlong YI Jian WU Chengzhi Ventura GUIDO LIU Pengcheng GUO Jiannan WANG Wei 
funded by the National Natural Science Foundation of China(Grant Nos.41972313 and 41790453);the Engineering Research Center of Geothermal Resources Development Technology and Equipment,Ministry of Education,Jilin University。
The 7 ka old Qixiangzhan lava flow(QXZ,Tianchi volcano)represents the last eruptive event before the 946 CE,caldera-forming‘Millennium’eruption(ME).Petrographic,whole rock,mineral composition,Sr-Nd isotopic data on ...
关键词：lava flow rhyolitic volcanism eruptive mechanism long-lived magmatic systems Tianchi volcano Qixiangzhan Formation 
Hearing loss prevalence and burden of disease in China:Findings from provincial-level analysis
《Chinese Medical Journal》2025年第1期41-48,共8页Yu Wang Yang Xie Minghao Wang Mengdan Zhao Rui Gong Ying Xin Jia Ke Ke Zhang Shaoxing Zhang Chen Du Qingchuan Duan Fang Wang Tao Pan Furong Ma Xiangyang Hu 
supported by grants from the Proof of Concept Program of Zhongguancun Science City and Peking University Third Hospital(No.HDCXZHKC2022211);the Theoretical and Practical Research Project of China Disabled Person’s Federation(2014–2015)(No.2014&ZZ028);Basic Scientific Research Fund of Central Universities(No.YWF-23-JT-103).
Background:Without timely and effective rehabilitation,hearing loss may profoundly affect human life quality.China has a large population of hearing-impaired individuals,which imposes a heavy health burden on society....
关键词：Hearing loss PREVALENCE SEVERITY Years lived with disability Burden of disease 
Extremely long-lived charge separation and related carrier spin excitation in CsPbBr_(3)perovskite quantum dots with an electron acceptor benzoquinone
《Nano Research》2024年第12期10649-10654,共6页Lin Cheng Rongrong Hu Meizhen Jiang Yumeng Men Yang Wang Jinlei Li Tianqing Jia Zhenrong Sun Donghai Feng 
supported by the National Natural Science Foundation of China(Nos.12174108,91950112,12104311,12074123,and 12034008).
The formation and evolution dynamics of charge separation(CS)in a complex of CsPbBr_(3) quantum dots(QDs)and 1,4-benzoquinone(BQ)molecules are measured with a high-sensitive pump-orientation-probe technique by which s...
关键词：charge separation perovskite quantum dots CsPbBr_(3) spin coherence pump-orientation-probe time-resolved ellipticity 
Progress in the creation of long-lived atmospheric luminous formations in a pulsed electric discharge with an electrolytic electrode
《Plasma Science and Technology》2024年第12期82-88,共7页Jingfeng YAO Jianfei LI Shixin ZHAO Chengxun YUAN Lin MIAO Nie CHEN A.M.ASTAFIEV A.A.KUDRYAVTSEV G.D.SHABANOV 
supported by Province Key R&D Program of Heilongjiang(No.JD22A005);National Natural Science Foundation of China(Nos.12175050 and 12205067)。
This work presents an analysis of the research conducted in many countries in recent years on the so-called Gatchina discharge.The findings indicate that the Gatchina discharge exhibits the majority of the characteris...
关键词：Gatchina discharge ball lightning SELF-ORGANIZATION dusty plasma 
Burden of biliary tract carcinoma in China(1990–2021):Findings from the 2021 Global Burden of Disease Study被引量：1
《Science Bulletin》2024年第22期3547-3557,共11页Wei Zhang Yi-Jun Wang Jiang-Mei Liu Xu-Heng Sun Yan Jiang Fang Shen Li-Juan Shen Jing Xiang Jun-Feng Zhang Lin-Hua Yang Wen-Guang Wu Tao Chen Hui Wang Min He Li-Guo Liu Wen-Qi Tao Yong-Zhi Chen Yong-Bing Xiang Mao-Lan Li Mai-Geng Zhou Ying-Bin Liu 
supported by the Key Program of Shanghai Science and Technology Commission(YDZX20193100004049);National Natural Science Foundation of China(82273016 and 82303937);Open Project of State Key Laboratory of Oncogenes and Related Genes(KF2120);National Key Project of Research and Development Program of China(2021YFC2500404 and 2021YFC2500405);the University-level Scientific Fund of Shanghai University of Medicine and Health Sciences(SSF-24-1602)。
Biliary tract carcinoma(BTC)is a group of malignant tumors that originate in the digestive system and occurs with a high incidence in China.Few consistent and comparable assessments of BTC disease burden have been con...
关键词：Biliary tract carcinoma China Global burden of disease study Disability-adjusted life-year Year of life lost due to premature death Year lived with disability 
Prediction of(n,2n)reaction cross-sections of long-lived fission products based on tensor model
《Nuclear Science and Techniques》2024年第10期208-221,共14页Jia-Li Huang Hui Wang Ying-Ge Huang Er-Xi Xiao Yu-Jie Feng Xin Lei Fu-Chang Gu Long Zhu Yong-Jing Chen Jun Su 
supported by the Key Laboratory of Nuclear Data foundation(No.JCKY2022201C157)。
Interest has recently emerged in potential applications of(n,2n)reactions of unstable nuclei.Challenges have arisen because of the scarcity of experimental cross-sectional data.This study aims to predict the(n,2n)reac...
关键词：(n 2n)Reaction cross-section Tensor model Machine learning Collaborative filtering algorithm Selective transmutation 
Intense Intramolecular Charge Transfer Endows Cyanated Polymer with Broad Absorption,Intensified Light-Harvesting,Long-Lived Exciton,and Superior Photovoltaic Property被引量：1
《CCS Chemistry》2024年第9期2318-2332,共15页Jinming Chen Huijuan Wang Songmin Mo Hui Chen Xinyu He Mingbin Su Dongyan Li Yonghong Xiao Zhiqi Wang Fanwei Ye Mingde Li Li Dang Xiao-Chun Huang Chang-Zhi Li Feng He Qinghe Wu 
supported by the National Natural Science Foundation of China(grant nos.22179076 and 22225504);the Department of Education of Guangdong Province,China(grant no.2021KCXTD032);the Natural Science Foundation of Guangdong Province,China(grant no.2022A1515011803);the Science and Technology Innovation Fund for College students in Guangdong Province,China(grant no.2020329105600A000003);Guangdong Provincial Key Laboratory of Catalysis,China(grant no.2020B121201002).
The donor–acceptor(D–A)copolymers,which exhibit wide broad absorption and intensified light-harvesting,are highly captivating for applications in solar conversion and optoelectronics.However,designing a polymer stru...
关键词：intramolecular charge transfer broad absorption band dicyanobenzotrithiophene cyanated polymer polymer solar cell 
Supernova 1987A's Keyhole:A Long-lived Jet-pair in the Final Explosion Phase of Core-collapse Supernovae
《Research in Astronomy and Astrophysics》2024年第7期89-94,共6页Noam Soker 
the Pazy Foundation supported this research。
I further study the manner by which a pair of opposite jets shape the“keyhole”morphological structure of the core-collapse supernova(CCSN)SN 1997A,now the CCSN remnant(CCSNR)1987A.By doing so,I strengthen the claim ...
关键词：STARS massive-(stars)supernovae general-(stars)supernovae individual(SN 1987A)-ISM supernova remnants-stars jets 
Physical mechanism of the rapid increase in intense and long-lived extreme heatwaves in the Northern Hemisphere since 1980
《Science China Earth Sciences》2024年第7期2103-2121,共19页Yuqing WANG Wen ZHOU Chunzai WANG 
supported by the National Natural Science Foundation of China(Grant Nos.42192563&42192564);the National Key R&D Program of China(Grant No.2019YFA0606701);the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB42000000);the Development Fund of South China Sea Institute of Oceanology of the Chinese Academy of Sciences(Grant No.SCSIO202208)。
Since 1980,both the intensity and duration of summer heatwaves in the middle and high latitudes of the Northern Hemisphere have significantly increased,leading this region to become a critical area for a significant i...
关键词：High intensity Long duration Extreme heatwaves High pressure system Soil moisture Cloud cover 
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