supported by grants from the National Key Research and Development Program of China(2018YFA0800700);the National Natural Science Foundation of China(92057207,32021003,92254308,92357303,323B1015,and 32271223);the 111 Project of China(B16036);the Key Research and Development Program of Hubei province(2019CFA067);Wuhan City(2020020601012211).
Lipoprotein lipase(LPL)mediates peripheral tissue triglyceride(TG)uptake.Hepatic ANGPTL3(A3)and ANGPTL8(A8)form a complex and inhibit LPL activity in the white adipose tissue(WAT)via systematic circulation.ANGPTL4(A4)...