MICROVESICLE

作品数：18被引量：336H指数：9
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相关领域：医药卫生生物学更多>>
相关作者：李润生赵茹茜杨晓静贾逸敏张辰宇更多>>
相关机构：南京大学南京农业大学更多>>
相关期刊：《Science China(Life Sciences)》《Acta Pharmacologica Sinica》《分子诊断与治疗杂志》《Genes & Diseases》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金更多>>
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Tumor-secreted miR-214 induces regulatory T cells： a major link between immune evasion and tumor growth被引量：36
《Cell Research》2014年第10期1164-1180,共17页Yuan Yin Xing Cai Xi Chen Hongwei Liang Yujing Zhang Jing Li Zuoyun Wang Xiulan Chen Wen Zhang Seiji Yokoyama Cheng Wang Liang Li Limin Li Dongxia Hou Lei Dong Tao Xu Takachika Hiroi Fuquan Yang Hongbin Ji Junfeng Zhang Ke Zen Chen-Yu Zhang 
We thank ProfAlexander Rudensky （Memorial Sloan-Kettering Cancer Center, New York） for diphtheria toxin-treated Foxp3DrR mice. We thank Drs Zheng-Gang Liu （Cancer Research Institute, NIH） and Dan Wu （Yale University） for their comments on the manuseirpt. This work was supported by grants from the National Basic Research Program of China （973 Program; 2014CB542300）, the National Natural Science Foundation of China （81101330, 31271378 and 81250044）, the Natural Science Foundation of Jiangsu Province （BK2011013 and BK2012014） and the Research Special Fund for Public Welfare Industry of Health （201302018）. This work was also supported by the program for New Century Excellent Talents in University from the Ministry of Education of China （NCET- 12-0261）.
An increased population of CD4＋CD25highFoxp3＋ regulatory T cells （Tregs） in the tumor-associated microenvi- ronment plays an important role in cancer immune evasion. However, the underlying mechanism remains uncle...
关键词：secreted microRNA regulatory T cell PTEN MICROVESICLE immune evasion TUMOR 
Exogenous plant MIR168a specifically targets mammalian LDLRAPI： evidence of cross-kingdom regulation by microRNA被引量：167
《Cell Research》2012年第1期107-126,共20页Lin Zhang Dongxia Hou Xi Chen Donghai Li Lingyun Zhu Yuj ing Zhang Jing Li Zhen Bian Xiangying Liang Xing Cai Yuan Yin Cheng Wang Tianfu Zhang Dihan Zhu Dianmu Zhang Jie Xu Qun Chen Yi Ba Jing Liu Qiang Wang Jianqun Chen Jin Wang Meng Wang Qipeng Zhang Junfeng Zhang Ke Zen Chen-Yu Zhang 
We thank Dr Daniel Wu （Yale University, USA） and Dr Zheng- Gang Liu （Cancer Research Institute, NIH, USA） for critical reading of the manuscript and discussion of data. This work was supported by grants from the National Natural Science Foundation of China （90813035, 30890044, 30771036, 30772484, 30725008, 30890032, 31071232, 31000323, and 90608010）, the National Basic Research Program of China （973 Program 2006CB503909, 2007CB815701, 2007CB815703, 2007CB815705, and 2007CB815804; 863 Program 2006AA02Z177 and 2006AA10A121）, and the Natural Science Foundation of Jiangsu Province （BK2008021）.
Our previous studies have demonstrated that stable microRNAs （miRNAs） in mammalian serum and plasma are actively secreted from tissues and cells and can serve as a novel class of biomarkers for diseases, and act as ...
关键词：MICRORNA MIR168a LDLRAP1 low-density lipoprotein MICROVESICLE cross-kingdom 
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