To quantitatively detect hypermethylation and to analyze methylation pattern, a methylation-specific oligonucleotide microarray for quantitative analysis was developed. The method used bisulfite-modified DNA as a temp...
Linkers were assembled on a glass surface based on the hydrolysis and condensation of 3-glycidoxy ̄propyltrimethoxysilane (GPS). After the assembly of GPS, four approaches were tried to open the ending epoxide group o...